Emergence of Adenomatous Aberrant Crypt Foci (ACF) from Hyperplastic ACF with Concomitant Increase in Cell Proliferation

Cancer Research

Volumn 55, Issue 21, 1995, Pages 4743-4746

  Otori, Kazuhiko ^a   Sugiyama, Kenji ^a   Esumi, Hiroyasu ^a   Hasebe, Takahiro ^a   Fukushima, Shoji ^b  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMA; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CHROMOSOME 12P; CODON; COLON MUCOSA; COLON TUMOR; COLORECTAL CANCER; CRYPT CELL; GENE MAPPING; GENE MUTATION; HUMAN; HUMAN TISSUE; HYPERPLASIA; ONCOGENE K RAS; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CODON; COLORECTAL NEOPLASMS; FEMALE; GENES, RAS; HUMAN; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MIDDLE AGE; MUTATION; PRECANCEROUS CONDITIONS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN P53; SUPPORT, NON-U.S. GOV'T;

EID: 0028824748     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Bird, R. P. Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen. Cancer Lett., 37: 149–151, 1987.
2. Pretlow, P. T., Cheyer, C., and O'Riordan, M. A. Aberrant crypt foci and colon tumors in F344 rats have similar increases in proliferative activity. Indian J. Cancer, 56: 599–602, 1994.
3. Yamashita, N., Minamoto, T., Onda, M., and Esumi, H. Increased cell proliferation of azoxymethane-induced aberrant crypt foci of rat colon. Jpn. J. Cancer Res., 85: 692–698, 1994.
4. Stopera, S., Murphy, L., and Bird, R. P. Evidence for ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats: earliest recognizable precursor lesion of experimental colon cancer. Carcinogenesis (Lond.), 13: 2081–2085, 1992.
5. Pretlow, T. P., Barrow, B. J., Ashton, W. S., O'Riordan, M. A., Pretlow, T. C., Jureisek, J. A., and Satellato, T. A. Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res., 51: 564–567, 1991.
6. Roncucci, L., Stamp, D., Medline, A., Cullen, J., and Bruce, W. Identification and quantification of aberrant crypt foci and microadenomas in the human colon. Hum. Pathol., 22: 287–294, 1991.
7. Roncucci, L., Medline, A., and Bruce, W. Classification of aberrant crypt foci and microadenomas in human colon. Cancer Epidemiol., Biomarkers & Prev., 1: 50–57, 1991.
8. Yamashita, N., Minamoto, T., Ochiai, A., Onda, M., and Esumi, H. Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon. Gastroenterology, 108: 434–440, 1994.
9. Yamashita, N., Minamoto, T., Ochiai, A., Onda, M., and Esumi, H. Frequent and characteristic K-ras activation in aberrant crypt foci of colon. Cancer (Phila.), 75: 1527–1533, 1995.
10. Jen, J., Powell, S. M., Papadopoulos, N., Smith, K. J., Hamilton S. R., Vogelstein, B., and Kinzler, K. W. Molecular determinations of dysplasia in colorectal lesions. Cancer Res., 54: 5523–5526, 1994.
11. Smith, A. J., Stem, S. S., Penner, M., Hay, K., Mitri, A., Bapat, B. V., and Gallinger, S. Somatic APC and K-ras codon 12 mutation in aberrant crypt foci from human colons. Cancer Res., 54: 5527–5530, 1994.
12. Pretlow, T. P., Brasitus, T. A., Fulton, N. C., Cheyer, C., and Kaplan, E. L. K-ras mutations in putative preneoplastic lesions in human colon. J. Natl. Cancer Inst., 85: 2004–2007, 1993.
13. Roncucci, L., Pedroni, M., Fante, R., Gregorio, C. D., and Leon, M. P. Cell kinetic evaluation of human colonic aberrant crypts. Cancer Res., 53: 3726–3729, 1993.
14. McLellan, E. A., Medline, A., and Bird, R. P. Sequential analyses of growth and morphological characteristic of aberrant crypt foci: putative preneoplastic lesions. Cancer Res., 51: 5270–5274, 1991.
15. Vogelstein, B., Feason, E. R., Hamilton, S. R., Kern, S. E., Preisinger, A. C., Leppert, M., Nakamura, Y., White, R., Smits, A. M. M., and Bos, J. L. Genetic alterations during colorectal-tumor development. N. Engl. J. Med., 319: 525–532, 1988.
16. Deschner, E. E. Adenomas: preneoplastic events, growth and development in man and experimental systems. Pathol. Annu., 18 (Part 1): 205–219, 1983.
17. Jass, J. R. Evolution of hereditary bowel cancer. Mutat. Res., 290: 13–25, 1993.
18. Minamoto, T., Sawaguchi, K., Mai, M., Yamashita, N., Sugimura, T., and Esumi, H. Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res., 54: 2841–2844, 1994.
19. Minamoto, T., Ronai, Z., Yamashita, N., Ochiai, A., Sugimura, T., Mai, M., and Esumi, H. Detection of Ki-ras mutation in non-neoplastic mucosa of Japanese patients with colorectal cancers. Int. J. Oncol., 4: 397–401, 1994.
20. Ronai, Z., Luo, F., Gradia, S., Hart, W., and Bulter, R. Detection of K-ras mutation in normal and malignant colonic tissues by enriched PCR method. Int. J. Oncol., 4: 391–396, 1994.
21. Kudo, S., Hirata, S., Nakajima, T., Hasebe, S., Kusaka, H., Kobayashi, T., Himori, M., and Yagyuu, A. Colorectal tumors and pit pattern. J. Clin. Pathol. (Lond.), 47: 880–885, 1994.
22. Yamagata, S., Muto, T., Uchida, Y., Masaki, T., Sawada, T., Tsuno, N., and Hirooka, T. Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas. Jpn. J. Cancer Res., 85: 147–151, 1994.
23. Fearon, R. E., and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759–767, 1990.