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Volumn 4, Issue 5, 1995, Pages 433-437

Clinical Experience with CD3 X CD19 Bispecific Antibodies in Patients with B Cell Malignancies

Author keywords

[No Author keywords available]

Indexed keywords

BISPECIFIC ANTIBODY; CD19 ANTIGEN; CD3 ANTIGEN; INTERLEUKIN 2;

EID: 0028824721     PISSN: 15258165     EISSN: none     Source Type: Journal    
DOI: 10.1089/scd.1.1995.4.433     Document Type: Article
Times cited : (69)

References (11)
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    • Weiner, G.J.1    DeGast, G.C.2
  • 2
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    • Killing of human leukaemia/lymphoma B cells by activated cytotoxic T lymphocytes in the presence of a bispecific monoclonal antibody (aCD3/aCD19)
    • Haagen, I-A., Van de Griend, R.J., Clark M., et al. Killing of human leukaemia/lymphoma B cells by activated cytotoxic T lymphocytes in the presence of a bispecific monoclonal antibody (aCD3/aCD19). Clin. Exp. Immunol. 90: 368, 1992.
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    • Haagen, I.-A.1    Van de Griend, R.J.2    Clark, M.3
  • 3
    • 0028360475 scopus 로고
    • KiUing of autologous B-lineage malignancy using CD3 X CD19 bispecific monoclonal antibody in end-stage leukemia and lymphoma
    • Haagen, I-A, Geerars, A, De Lau, W.B., et al. KiUing of autologous B-lineage malignancy using CD3 X CD19 bispecific monoclonal antibody in end-stage leukemia and lymphoma. Blood 84:556, 1994.
    • (1994) Blood , vol.84 , pp. 556
    • Haagen, I.-A.1    Geerars, A.2    De Lau, W.B.3
  • 4
    • 0028171628 scopus 로고
    • Evaluation of Fey receptor-mediated T cell activation by two purified CDS X CD 19 bispecific monoclonal antibodies with hybrid Fc domains
    • Haagen, I-A., Geerars, A.J.G., Bast, E.J.E.G., et al. Evaluation of Fey receptor-mediated T cell activation by two purified CDS X CD 19 bispecific monoclonal antibodies with hybrid Fc domains. Ther. Immunol. 1:279, 1994.
    • (1994) Ther. Immunol. , vol.1 , pp. 279
    • Haagen, I.-A.1    Geerars, A.J.G.2    Bast, E.J.E.G.3
  • 5
    • 0028109446 scopus 로고
    • Unprimed CD4+ and CD8+ T cells can be rapidly activated by CD3 X CD 19 bispecific antibody to proliferate and become cytotoxic
    • Haagen, I-A., De Lau, W.B.M., Bast B.J.E.G., et al. Unprimed CD4+ and CD8+ T cells can be rapidly activated by CD3 X CD 19 bispecific antibody to proliferate and become cytotoxic. Cancer Immunol. Immunother. 39:391, 1994.
    • (1994) Cancer Immunol. Immunother. , vol.39 , pp. 391
    • Haagen, I.-A.1    De Lau, W.B.M.2    Bast, B.J.E.G.3
  • 6
    • 0029014218 scopus 로고
    • The efficacy of CD3 X CD 19 BsAb in a clonogenic assay: The effect of repeated addition of bispecific antibody and IL
    • Haagen, I-A., Geerars, A.J.G., De Lau, W.B.M., et al. The efficacy of CD3 X CD 19 BsAb in a clonogenic assay: The effect of repeated addition of bispecific antibody and IL. Blood 85:3208, 1995.
    • (1995) Blood , vol.85 , pp. 3208
    • Haagen, I.-A.1    Geerars, A.J.G.2    De Lau, W.B.M.3
  • 7
    • 0029062025 scopus 로고
    • CD8 T cell activation after intravenous administration of CD3 X CD 19 bispecific antibody in patients with non-Hodgkin lymphoma
    • De Gast, G.C., Haagen, I-A., Van Houten, A.A., et al. CD8 T cell activation after intravenous administration of CD3 X CD 19 bispecific antibody in patients with non-Hodgkin lymphoma. Cancer Immunol. Immunother. 40:390, 1995.
    • (1995) Cancer Immunol. Immunother. , vol.40 , pp. 390
    • De Gast, G.C.1    Haagen, I.-A.2    Van Houten, A.A.3
  • 8
    • 0026474226 scopus 로고
    • Bispecific IgG and IL-2 therapy of a syngeneic B-cell lymphoma in immunodeficient mice
    • Weiner, G.J. Bispecific IgG and IL-2 therapy of a syngeneic B-cell lymphoma in immunodeficient mice. Int. J. Cancer 7:63, 1992.
    • (1992) Int. J. Cancer , vol.7 , pp. 63
    • Weiner, G.J.1
  • 9
    • 0027281795 scopus 로고
    • Lysis of malignant B-cells from patients with B-chronic lymphocytic leukemia by autologous T-cells activated with CD3 X CD 19 bispecific antibodies in combination with bivalent CD28 antibodies
    • Bohlen, H., Hopff, T., Manzke, O., et al. Lysis of malignant B-cells from patients with B-chronic lymphocytic leukemia by autologous T-cells activated with CD3 X CD 19 bispecific antibodies in combination with bivalent CD28 antibodies. Blood 82:1803, 1993.
    • (1993) Blood , vol.82 , pp. 1803
    • Bohlen, H.1    Hopff, T.2    Manzke, O.3
  • 10
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    • Cytolysis of leukemia B cells by T cells activated via 2 bispecific antibodies
    • Bohlen, H. Manzke, O., Patel, B., et al. Cytolysis of leukemia B cells by T cells activated via 2 bispecific antibodies. Cancer Res. 53:4310, 1993.
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    • Bohlen, H.1    Manzke, O.2    Patel, B.3
  • 11
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    • O'Brien, S., Kantarjian, H., Beran, M., et al. Results of flu-darabine and prednisone therapy in 264 patients with chronic lymphocytic leukemia with multivariate analysis-derived prognostic model for response to treatment. Blood 82:1695, 1993.
    • (1993) Blood , vol.82 , pp. 1695
    • O'Brien, S.1    Kantarjian, H.2    Beran, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.