-
1
-
-
0027985294
-
Sites of accumulation of the antitumor alkaloid camptothecin in Camptotheca acuminata
-
Lopez-Meyer, M., Nessler, C. L., and McKnight, T. D. Sites of accumulation of the antitumor alkaloid camptothecin in Camptotheca acuminata. Planta Med., 60: 558–560, 1994.
-
(1994)
Planta Med.
, vol.60
, pp. 558-560
-
-
Lopez-Meyer, M.1
Nessler, C.L.2
McKnight, T.D.3
-
2
-
-
7144248725
-
Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata
-
Wall, M. E., Wani, M. C., Cook, C. E., Palmer, K. H., McPhail, A. T., and Sim, G. A. Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. J. Am. Chem. Soc., 88: 3888–3890, 1966.
-
(1966)
J. Am. Chem. Soc.
, vol.88
, pp. 3888-3890
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
Palmer, K.H.4
McPhail, A.T.5
Sim, G.A.6
-
3
-
-
0015212040
-
Intracellular degradation of HeLa and adenovirus type 2 DNA induced by camptothecin
-
Horwitz, M. S., and Horwitz, S. B. Intracellular degradation of HeLa and adenovirus type 2 DNA induced by camptothecin. Biochem. Biophys. Res. Commun., 45: 723–727, 1971.
-
(1971)
Biochem. Biophys. Res. Commun.
, vol.45
, pp. 723-727
-
-
Horwitz, M.S.1
Horwitz, S.B.2
-
4
-
-
0015241290
-
Effects of camptothecin on RNA synthesis in leukemia L1210 cells
-
Kessel, D. Effects of camptothecin on RNA synthesis in leukemia L1210 cells. Biochim. Biophys. Acta, 246: 225–232, 1971.
-
(1971)
Biochim. Biophys. Acta
, vol.246
, pp. 225-232
-
-
Kessel, D.1
-
5
-
-
0015150039
-
Studies on camptothecin. 1. Effects on nucleic acid and protein synthesis
-
Horwitz, S. B., Chang, C-K., and Grollman, A. P. Studies on camptothecin. 1. Effects on nucleic acid and protein synthesis. Mol. Pharmacol., 7; 632–644, 1971.
-
(1971)
Mol. Pharmacol.
, vol.7
, pp. 632-644
-
-
Horwitz, S.B.1
Chang, C.-K.2
Grollman, A.P.3
-
6
-
-
0015174240
-
Ribosomal formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis
-
Wu, R. S., Kumar, A., and Warner, J. R. Ribosomal formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis. Proc. Natl. Acad. Sci. USA, 68: 3009–3014, 1971.
-
(1971)
Proc. Natl. Acad. Sci. USA
, vol.68
, pp. 3009-3014
-
-
Wu, R.S.1
Kumar, A.2
Warner, J.R.3
-
7
-
-
0015500913
-
Camptothecin effects on DNA synthesis of murine leukemia cells
-
Kessel, D., Bosmann, H. B., and Lohr, K. Camptothecin effects on DNA synthesis of murine leukemia cells. Biochim. Biophys. Acta, 269: 210–216, 1972.
-
(1972)
Biochim. Biophys. Acta
, vol.269
, pp. 210-216
-
-
Kessel, D.1
Bosmann, H.B.2
Lohr, K.3
-
8
-
-
0015530742
-
Selective interruption of high molecular weight RNA synthesis in HeLa cells by camptothecin
-
Abelson, H. T., and Penman, S. Selective interruption of high molecular weight RNA synthesis in HeLa cells by camptothecin. Nature (Lond.), 237: 144–146, 1972.
-
(1972)
Nature (Lond.)
, vol.237
, pp. 144-146
-
-
Abelson, H.T.1
Penman, S.2
-
9
-
-
0025335205
-
Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription
-
Bendixen, C, Thomsen, B., Alsner, J., and Westergaard, O. Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription. Biochemistry, 12: 5613–5619, 1990.
-
(1990)
Biochemistry
, vol.12
, pp. 5613-5619
-
-
Bendixen, C.1
Thomsen, B.2
Alsner, J.3
Westergaard, O.4
-
10
-
-
0014895176
-
Preliminary pharmacological and clinical evaluation of camptothecin sodium (NCS 100880)
-
Gottlieb, J. A., Guarino, A. M., Call, J. B., and Block, J. B. Preliminary pharmacological and clinical evaluation of camptothecin sodium (NCS 100880). Cancer Chemother. Rep., 54: 461–470, 1970.
-
(1970)
Cancer Chemother. Rep.
, vol.54
, pp. 461-470
-
-
Gottlieb, J.A.1
Guarino, A.M.2
Call, J.B.3
Block, J.B.4
-
11
-
-
0015291595
-
Phase II study of camptothecin (NSC 100880) in the treatment of advanced gastrointestinal cancer
-
Moertel, C. G., Schutt, A. J., Reitemeier, R. J., and Hahn, R. G. Phase II study of camptothecin (NSC 100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother. Rep., 56: 95–101, 1972.
-
(1972)
Cancer Chemother. Rep.
, vol.56
, pp. 95-101
-
-
Moertel, C.G.1
Schutt, A.J.2
Reitemeier, R.J.3
Hahn, R.G.4
-
12
-
-
0015292126
-
Treatment of malignant melanoma with camptothecin (NSC 100880)
-
Gottlieb, J. A., and Luce, J. K. Treatment of malignant melanoma with camptothecin (NSC 100880). Cancer Chemother. Rep., 56: 103–105, 1972.
-
(1972)
Cancer Chemother. Rep.
, vol.56
, pp. 103-105
-
-
Gottlieb, J.A.1
Luce, J.K.2
-
13
-
-
0015378084
-
Phase I clinical trials of weekly and daily treatment with camptothecin (NSC 100880). Correlation with clinical studies
-
Muggia, F. M., Creaven, P. T., Hansen, H. H., Cohen, M. N., and Selawny, D. S. Phase I clinical trials of weekly and daily treatment with camptothecin (NSC 100880). Correlation with clinical studies. Cancer Chemother. Rep., 56: 515–521, 1972.
-
(1972)
Cancer Chemother. Rep.
, vol.56
, pp. 515-521
-
-
Muggia, F.M.1
Creaven, P.T.2
Hansen, H.H.3
Cohen, M.N.4
Selawny, D.S.5
-
14
-
-
0343029631
-
Chemistry and antitumor activities of camptothecins
-
M. Potmesil and K. W. Kohn (eds.), New York: Oxford University Press
-
Wall, M. E., and Wani, M. C. Chemistry and antitumor activities of camptothecins. In: M. Potmesil and K. W. Kohn (eds.), DNA Topoisomerases in Cancer, pp. 93–102. New York: Oxford University Press, 1991.
-
(1991)
DNA Topoisomerases in Cancer
, pp. 93-102
-
-
Wall, M.E.1
Wani, M.C.2
-
15
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang, Y-H., Hertzberg, R., Hecht, S., and Liu, L. F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J. Biol. Chem., 260: 14873–14878, 1985.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.-H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
16
-
-
0023924786
-
Identification of mammalian topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
Hsiang, Y-H., and Liu, L. F. Identification of mammalian topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res., 48: 1722–1726, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 1722-1726
-
-
Hsiang, Y.-H.1
Liu, L.F.2
-
17
-
-
0024324205
-
On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
-
Hertzberg, R., Caranfa, M., and Hecht, S. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. Biochemistry, 28: 4629–4638, 1989.
-
(1989)
Biochemistry
, vol.28
, pp. 4629-4638
-
-
Hertzberg, R.1
Caranfa, M.2
Hecht, S.3
-
18
-
-
0024560495
-
Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity
-
Jaxel, C., Kohn, K. W., Wani, M. C., Wall, M. E., and Pommier, Y. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. Cancer Res., 49: 1465–1469, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 1465-1469
-
-
Jaxel, C.1
Kohn, K.W.2
Wani, M.C.3
Wall, M.E.4
Pommier, Y.5
-
19
-
-
0024356003
-
DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogs
-
Hsiang, Y-H., Liu, L. F., Wall, M. E., Wani, M. C., Kirshenbaum, S., Silber, R., and Potmesil, M. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogs. Cancer Res., 49: 4385–4389, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 4385-4389
-
-
Hsiang, Y.-H.1
Liu, L.F.2
Wall, M.E.3
Wani, M.C.4
Kirshenbaum, S.5
Silber, R.6
Potmesil, M.7
-
20
-
-
0024358188
-
DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
-
Giovanella, B. C., Stehlin, J. S., Wall, M. E., Wani, M. C., Nicholas, A. W., Liu, L. F., Silber, R., and Potmesil, M. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science (Washington DC), 246: 1046–1048, 1989.
-
(1989)
Science (Washington DC)
, vol.246
, pp. 1046-1048
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Wall, M.E.3
Wani, M.C.4
Nicholas, A.W.5
Liu, L.F.6
Silber, R.7
Potmesil, M.8
-
21
-
-
0025912553
-
Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20(5)-camptothecin
-
Giovanella, B. C., Hinz, H. R., Kozielski, A. J., Stehlin, J. S., Silber, R., and Potmesil, M. Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20(5)-camptothecin. Cancer Res., 51: 3052–3055, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 3052-3055
-
-
Giovanella, B.C.1
Hinz, H.R.2
Kozielski, A.J.3
Stehlin, J.S.4
Silber, R.5
Potmesil, M.6
-
22
-
-
0026694680
-
Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice by camptothecins
-
Pantazis, P., Hinz, H. R., Mendoza, J. T., Kozielski, A. J., Williams, L. J., Stehlin, J. S., and Giovanella, B. C. Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice by camptothecins. Cancer Res., 52: 3980–3987, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 3980-3987
-
-
Pantazis, P.1
Hinz, H.R.2
Mendoza, J.T.3
Kozielski, A.J.4
Williams, L.J.5
Stehlin, J.S.6
Giovanella, B.C.7
-
24
-
-
0023552964
-
Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
-
Kunimoto, T., Nitta, K., Tanaka, T., Uehara, N., Baba, H., Takeuchi, M., Yokokura, T., Sawada, S., Miyasaka, T., and Mutai, M. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino] carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res., 47: 5944–5947, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 5944-5947
-
-
Kunimoto, T.1
Nitta, K.2
Tanaka, T.3
Uehara, N.4
Baba, H.5
Takeuchi, M.6
Yokokura, T.7
Sawada, S.8
Miyasaka, T.9
Mutai, M.10
-
25
-
-
0026099599
-
Synthesis of water-soluble (aminoalkyl) camptothecin analogues: inhibition of topoisomerase I and antitumor activity
-
Kingsbury, W. D., Boehm, J. C., Jakas, D. R., Holden, K. G., Hecht, S. M., Gallagher, G., Caranfa, M. J., McCabe, F. L., Faucette, L. F., Johnson, R. K., and Hertzberg, R. P. Synthesis of water-soluble (aminoalkyl) camptothecin analogues: inhibition of topoisomerase I and antitumor activity. J. Med. Chem., 34: 98–107, 1991.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 98-107
-
-
Kingsbury, W.D.1
Boehm, J.C.2
Jakas, D.R.3
Holden, K.G.4
Hecht, S.M.5
Gallagher, G.6
Caranfa, M.J.7
McCabe, F.L.8
Faucette, L.F.9
Johnson, R.K.10
Hertzberg, R.P.11
-
26
-
-
0027201885
-
Preferential binding of the carboxylate form of camptothecin by human serum albumin
-
Burke, T. G., and Mi, Z. Preferential binding of the carboxylate form of camptothecin by human serum albumin. Anal. Biochem., 212: 285–287, 1993.
-
(1993)
Anal. Biochem.
, vol.212
, pp. 285-287
-
-
Burke, T.G.1
Mi, Z.2
-
27
-
-
0027930186
-
Differential interactions of camptothecin lactone and carboxylate forms with human blood components
-
Mi, Z., and Burke, T. G. Differential interactions of camptothecin lactone and carboxylate forms with human blood components. Biochemistry, 33: 10325–10336, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 10325-10336
-
-
Mi, Z.1
Burke, T.G.2
-
28
-
-
0028937909
-
The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs
-
Burke, T. G., Munshi, C. B., Mi, Z., and Jiang, Y. The important role of albumin in determining the relative human blood stabilities of the camptothecin anticancer drugs. J. Pharm. Sci., 84: 518–519, 1995.
-
(1995)
J. Pharm. Sci.
, vol.84
, pp. 518-519
-
-
Burke, T.G.1
Munshi, C.B.2
Mi, Z.3
Jiang, Y.4
-
29
-
-
2642660618
-
Topoisomerase I inhibitors: promising novel compounds
-
Eckardt, J. R., Burris, H. A., Rothenberg, M. L., Von Hoff, D. D., and Kuhn, J. G. Topoisomerase I inhibitors: promising novel compounds. Contemp. Oncol. Jan.: 47–60, 1993.
-
(1993)
Contemp. Oncol. Jan.
, pp. 47-60
-
-
Eckardt, J.R.1
Burris, H.A.2
Rothenberg, M.L.3
Von Hoff, D.D.4
Kuhn, J.G.5
-
30
-
-
0027972726
-
Topoisomerase I inhibitors: topotecan and irinotecan
-
Creemers, G. J., Lund, B., and Verweij, J. Topoisomerase I inhibitors: topotecan and irinotecan. Cancer Treat. Rev., 20: 73–96, 1994.
-
(1994)
Cancer Treat. Rev.
, vol.20
, pp. 73-96
-
-
Creemers, G.J.1
Lund, B.2
Verweij, J.3
-
31
-
-
34548192940
-
Topoisomerase I inhibitors: a new class of anticancer agents
-
Bowen, K., Fields, S., and Buris, H. Topoisomerase I inhibitors: a new class of anticancer agents. Adv. Oncol., 10: 16–21, 1994.
-
(1994)
Adv. Oncol.
, vol.10
, pp. 16-21
-
-
Bowen, K.1
Fields, S.2
Buris, H.3
-
32
-
-
0028267240
-
Camptothecins: from bench research to hospital wards
-
Potmesil, M. Camptothecins: from bench research to hospital wards. Cancer Res., 54: 1431–1439, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1431-1439
-
-
Potmesil, M.1
-
33
-
-
0028225471
-
Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials
-
Tanizawa, A., Fujimori, A., Fujimori, Y., and Pommier, Y. Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials. J. Natl. Cancer Inst., 86: 836–842, 1994.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 836-842
-
-
Tanizawa, A.1
Fujimori, A.2
Fujimori, Y.3
Pommier, Y.4
-
34
-
-
0027399619
-
9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro
-
Pantazis, P., Mendoza, J. T., Kozielski, A. J., Natelson, E. A., and Giovanella, B. C. 9-Nitro-camptothecin delays growth of U-937 leukemia tumors in nude mice and is cytotoxic or cytostatic for human myelomonocytic leukemia lines in vitro. Eur. J. Haematol., 50: 81–89, 1993.
-
(1993)
Eur. J. Haematol.
, vol.50
, pp. 81-89
-
-
Pantazis, P.1
Mendoza, J.T.2
Kozielski, A.J.3
Natelson, E.A.4
Giovanella, B.C.5
-
35
-
-
0027467836
-
Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitro-camptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro
-
Pantazis, P., Early, J. A., Kozielski, A. J., Mendoza, J. T., Hinz, H. R., and Giovanella, B. C. Regression of human breast carcinoma tumors in immunodeficient mice treated with 9-nitro-camptothecin: differential response of nontumorigenic and tumorigenic human breast cells in vitro. Cancer Res., 53: 1577–1582, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 1577-1582
-
-
Pantazis, P.1
Early, J.A.2
Kozielski, A.J.3
Mendoza, J.T.4
Hinz, H.R.5
Giovanella, B.C.6
-
36
-
-
0027471350
-
Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro
-
Pantazis, P., Kozielski, A. J., Mendoza, J. T., Early, J. A., Hinz, H. R., and Giovanella, B. C. Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro. Int. J. Cancer, 53: 863–871, 1993.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 863-871
-
-
Pantazis, P.1
Kozielski, A.J.2
Mendoza, J.T.3
Early, J.A.4
Hinz, H.R.5
Giovanella, B.C.6
-
37
-
-
0028127960
-
Cytotoxic efficacy of 9-nitrocamptothecin in the treatment of human malignant melanoma cells in vitro
-
Pantazis, P., Early, J. A., Mendoza, J. T., DeJesus, A. R., and Giovanella, B. C. Cytotoxic efficacy of 9-nitrocamptothecin in the treatment of human malignant melanoma cells in vitro. Cancer Res., 54: 771–776, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 771-776
-
-
Pantazis, P.1
Early, J.A.2
Mendoza, J.T.3
DeJesus, A.R.4
Giovanella, B.C.5
-
38
-
-
0027817002
-
Efficacy of camptothecin congeners in the treatment of human breast carcinoma xenografts
-
Pantazis, P., Kozielski, A. J., Vardeman, D. M., Petry, E. R., and Giovanella, B. C. Efficacy of camptothecin congeners in the treatment of human breast carcinoma xenografts. Oncol. Res., 5: 273–281, 1993.
-
(1993)
Oncol. Res.
, vol.5
, pp. 273-281
-
-
Pantazis, P.1
Kozielski, A.J.2
Vardeman, D.M.3
Petry, E.R.4
Giovanella, B.C.5
-
39
-
-
0028278524
-
Therapeutic efficacy of camptothecin-derivatives against human malignant melanoma xenografts
-
Pantazis, P., Kozielski, A., Rodriguez, R., Petry, E., Wall, M., and Giovanella, B. C. Therapeutic efficacy of camptothecin-derivatives against human malignant melanoma xenografts. Melanoma Res., 4: 5–10, 1994.
-
(1994)
Melanoma Res.
, vol.4
, pp. 5-10
-
-
Pantazis, P.1
Kozielski, A.2
Rodriguez, R.3
Petry, E.4
Wall, M.5
Giovanella, B.C.6
-
40
-
-
0002428894
-
Phase I clinical trial and pharmacokinetics results with oral administration of 20(5)-camptothecin
-
M. Potmesil and H. Pinedo (eds.), Boca Raton, FL: CRC Press, Inc.
-
Stehlin, J. S., Natelson, E. A., Hinz, H. R., Giovanella, B. C., de Ipolyi, P. D., Fehir, K. M., Trezona, T. P., Vardeman, D. M., Harris, N. J., Marcee, A. K., Kozielski, A. J., and Ruiz-Razura, A. Phase I clinical trial and pharmacokinetics results with oral administration of 20(5)-camptothecin. In: M. Potmesil and H. Pinedo (eds.), Camptothecins: New Anticancer Agents, pp. 59–65. Boca Raton, FL: CRC Press, Inc., 1995.
-
(1995)
Camptothecins: New Anticancer Agents
, pp. 59-65
-
-
Stehlin, J.S.1
Natelson, E.A.2
Hinz, H.R.3
Giovanella, B.C.4
de Ipolyi, P.D.5
Fehir, K.M.6
Trezona, T.P.7
Vardeman, D.M.8
Harris, N.J.9
Marcee, A.K.10
Kozielski, A.J.11
Ruiz-Razura, A.12
-
41
-
-
0028678055
-
Clinical development of topoisomerase-interactive drugs
-
Muggia, F. M., and Burris, H. A. Clinical development of topoisomerase-interactive drugs. Adv. Pharmacol., 29A: 1–31, 1995.
-
(1995)
Adv. Pharmacol.
, vol.29A
, pp. 1-31
-
-
Muggia, F.M.1
Burris, H.A.2
-
43
-
-
0028904703
-
A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin
-
Rubin, E., Wood, V., Bharti, A., Trites, D., Lynch, C, Hurwitz, S., Bartel, S., Levy, S., Rosowsky, A., Toppmeyer, D., and Kufe, D. A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin. Clin. Cancer Res., 1: 269–276, 1995.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 269-276
-
-
Rubin, E.1
Wood, V.2
Bharti, A.3
Trites, D.4
Lynch, C.5
Hurwitz, S.6
Bartel, S.7
Levy, S.8
Rosowsky, A.9
Toppmeyer, D.10
Kufe, D.11
-
44
-
-
84969050947
-
Topoisomerase I inhibitors
-
In: B. Teicher (ed.), New York: Academic Press, in press
-
Giovanella, B. Topoisomerase I inhibitors. In: B. Teicher (ed.), Cancer Drug Discovery. New York: Academic Press, in press, 1995.
-
(1995)
Cancer Drug Discovery
-
-
Giovanella, B.1
-
45
-
-
0028292475
-
Pharmacokinetics of the in vivo and in vitro conversion of 9-nitro-20(S)-camptothecin to 9-amino-20(S)-camptothecin in human, dog and mouse
-
Hinz, H. R., Harris, N. J., Natelson, E. A., and Giovanella, B. C. Pharmacokinetics of the in vivo and in vitro conversion of 9-nitro-20(S)-camptothecin to 9-amino-20(S)-camptothecin in human, dog and mouse. Cancer Res., 54: 3096–3100, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3096-3100
-
-
Hinz, H.R.1
Harris, N.J.2
Natelson, E.A.3
Giovanella, B.C.4
-
46
-
-
0028032929
-
Conversion of 9-nitro-camptothecin to 9-amino-camptothecin by human blood cells in vitro
-
Pantazis, P., Harris, N., Mendoza, J., and Giovanella, B. Conversion of 9-nitro-camptothecin to 9-amino-camptothecin by human blood cells in vitro. Eur. J. Haematol., 53: 246–248, 1994.
-
(1994)
Eur. J. Haematol.
, vol.53
, pp. 246-248
-
-
Pantazis, P.1
Harris, N.2
Mendoza, J.3
Giovanella, B.4
-
47
-
-
0029085565
-
The role of pH and serum albumin in the metabolic conversion of 9-nitrocamptothecin to 9-aminocamptothecin by human hematopoietic and other cells
-
Pantazis, P., Harris, N., Mendoza, J., and Giovanella, B. The role of pH and serum albumin in the metabolic conversion of 9-nitrocamptothecin to 9-aminocamptothecin by human hematopoietic and other cells. Eur. J. Haematol., 55: 211–213, 1995.
-
(1995)
Eur. J. Haematol.
, vol.55
, pp. 211-213
-
-
Pantazis, P.1
Harris, N.2
Mendoza, J.3
Giovanella, B.4
-
48
-
-
0002591057
-
DNA topoisomerases as targets of therapeutics: a structural overview
-
T. Ando, H. Ikeda, and M. Oguro (eds.), Boca Raton, FL: CRC Press, Inc.
-
Caron, P., and Wang, J. C. DNA topoisomerases as targets of therapeutics: a structural overview. In: T. Ando, H. Ikeda, and M. Oguro (eds.), Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy, pp. 1–18. Boca Raton, FL: CRC Press, Inc., 1993.
-
(1993)
Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy
, pp. 1-18
-
-
Caron, P.1
Wang, J.C.2
-
49
-
-
0003614558
-
-
(eds.), Boca Raton, FL: CRC Press, Inc.
-
In: T. Andoh, H. Ikeda, and M. Oguro (eds.), Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy. Boca Raton, FL: CRC Press, Inc., 1993.
-
(1993)
Molecular Biology of DNA Topoisomerases and Its Application to Chemotherapy
-
-
Andoh, T.1
Ikeda, H.2
Oguro, M.3
-
50
-
-
0003295391
-
DNA topoisomerases: biochemistry and molecular biology
-
Liu, L. F. DNA topoisomerases: biochemistry and molecular biology. Adv. Pharmacol., 29A: 1994.
-
(1994)
Adv. Pharmacol.
, vol.29A
-
-
Liu, L.F.1
-
51
-
-
0001929297
-
Structure-activity relationship of topoisomerase I inhibition by camptothecin derivatives: evidence for the existence of a ternary complex
-
M. Potmesil and K. W. Kohn (eds.), New York: Oxford University Press
-
Pommier, Y., Jaxel, C, Heise, C. R., Kerrigan, D., and Kohn, K. W. Structure-activity relationship of topoisomerase I inhibition by camptothecin derivatives: evidence for the existence of a ternary complex. In: M. Potmesil and K. W. Kohn (eds.), DNA Topoisomerase in Cancer, pp. 121–132. New York: Oxford University Press, 1991.
-
(1991)
DNA Topoisomerase in Cancer
, pp. 121-132
-
-
Pommier, Y.1
Jaxel, C.2
Heise, C.R.3
Kerrigan, D.4
Kohn, K.W.5
-
52
-
-
0025719903
-
Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
-
Jaxel, C, Capranico, G., Kerrigan, D., Kohn, K., and Pommier, Y. Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J. Biol. Chem., 266: 20418–20423, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 20418-20423
-
-
Jaxel, C.1
Capranico, G.2
Kerrigan, D.3
Kohn, K.4
Pommier, Y.5
-
53
-
-
0024469050
-
The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I
-
Porter, S. E., and Champoux, J. J. The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. Nucleic Acids Res., 17: 8521–8532, 1989.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 8521-8532
-
-
Porter, S.E.1
Champoux, J.J.2
-
54
-
-
0019888076
-
DNA is linked to the rat liver nicking-dosing enzyme by a phosphodiester bond to tyrosine
-
Champoux, J. J. DNA is linked to the rat liver nicking-dosing enzyme by a phosphodiester bond to tyrosine. J. Biol. Chem., 256: 4805–4809, 1981.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 4805-4809
-
-
Champoux, J.J.1
-
55
-
-
0027290438
-
Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm
-
Leteurtre, F., Fesen, M., Kohlhagen, G., Kohn, K. W., and Pommier, Y. Specific interaction of camptothecin, a topoisomerase I inhibitor, with guanine residues of DNA detected by photoactivation at 365 nm. Biochemistry, 32: 8955–8962, 1993.
-
(1993)
Biochemistry
, vol.32
, pp. 8955-8962
-
-
Leteurtre, F.1
Fesen, M.2
Kohlhagen, G.3
Kohn, K.W.4
Pommier, Y.5
-
56
-
-
0025276858
-
A model for tumor cell killing by topoisomerase poisons
-
Zhang, H., D'Arpa, P., and Liu, L. A model for tumor cell killing by topoisomerase poisons. Cancer Cells (Cold Spring Harbor), 2: 23–27, 1990.
-
(1990)
Cancer Cells (Cold Spring Harbor)
, vol.2
, pp. 23-27
-
-
Zhang, H.1
D'Arpa, P.2
Liu, L.3
-
57
-
-
0024420685
-
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
-
Hsiang, Y-H., Lihou, M. G., and Liu, L. F. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res., 49: 5077–5082, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.-H.1
Lihou, M.G.2
Liu, L.F.3
-
58
-
-
0027139317
-
Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system
-
Tsao, Y-P., Russo, A., Nyamuswa, G., Silber, R., and Liu, L. F. Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. Cancer Res., 53: 5908–5914, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5908-5914
-
-
Tsao, Y.-P.1
Russo, A.2
Nyamuswa, G.3
Silber, R.4
Liu, L.F.5
-
59
-
-
0027243234
-
DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells. Jpn.
-
Yoshida, A., Ueda, T., Wano, Y., and Nakamura, T. DNA damage and cell killing by camptothecin and its derivative in human leukemia HL-60 cells. Jpn. J. Cancer Res., 84: 566–573, 1993.
-
(1993)
J. Cancer Res.
, vol.84
, pp. 566-573
-
-
Yoshida, A.1
Ueda, T.2
Wano, Y.3
Nakamura, T.4
-
60
-
-
0015044313
-
Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin
-
Gallo, R. C., Whang-Peng, J., and Adamson, R. H. Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin. J. Natl. Cancer Inst., 46: 789–795, 1971.
-
(1971)
J. Natl. Cancer Inst.
, vol.46
, pp. 789-795
-
-
Gallo, R.C.1
Whang-Peng, J.2
Adamson, R.H.3
-
61
-
-
0025043807
-
Diverse effects of camptothecin, an inhibitor of topoisomerase I, on the cell cycle of lymphocytic (L1210, MOLT-4) and myelogenous (HL-60, KG-1) leukemia cells
-
Del Bino, G., Skierski, J. S., and Darzynkiewicz, Z. Diverse effects of camptothecin, an inhibitor of topoisomerase I, on the cell cycle of lymphocytic (L1210, MOLT-4) and myelogenous (HL-60, KG-1) leukemia cells. Cancer Res., 50: 5746–5750, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 5746-5750
-
-
Del Bino, G.1
Skierski, J.S.2
Darzynkiewicz, Z.3
-
62
-
-
0025133118
-
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons
-
D'Arpa, P., Beardmore, C, and Liu, L. F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res., 50: 6919–6924, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 6919-6924
-
-
D'Arpa, P.1
Beardmore, C.2
Liu, L.F.3
-
63
-
-
0025877991
-
Camptothecin, teniposide, or 4′-(9-acridinyl-amino)-3-methanesulfon-m-anisidide, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S-phase of HL-60 cells
-
Del Bino, G., and Darzynkiewicz, Z. Camptothecin, teniposide, or 4′-(9-acridinyl-amino)-3-methanesulfon-m-anisidide, but not mitoxantrone or doxorubicin, induces degradation of nuclear DNA in the S-phase of HL-60 cells. Cancer Res., 51: 1165–1169, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 1165-1169
-
-
Del Bino, G.1
Darzynkiewicz, Z.2
-
64
-
-
0026331895
-
Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells
-
Kharbanda, S., Rubin, E., Gunji, H., Hinz, H., Giovanella, B., Pantazis, P., and Kufe, D. Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells. Cancer Res., 51: 6636–6642, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6636-6642
-
-
Kharbanda, S.1
Rubin, E.2
Gunji, H.3
Hinz, H.4
Giovanella, B.5
Pantazis, P.6
Kufe, D.7
-
65
-
-
0026492817
-
Features of apoptotic cells by flow cytometry
-
Darzynkiewicz, Z., Bruno, S., Del Bino, G., Gorczyca, W., Hotz, M. A., Lassota, P., and Traganos, F. Features of apoptotic cells by flow cytometry. Cytometry, 13: 795–808, 1992.
-
(1992)
Cytometry
, vol.13
, pp. 795-808
-
-
Darzynkiewicz, Z.1
Bruno, S.2
Del Bino, G.3
Gorczyca, W.4
Hotz, M.A.5
Lassota, P.6
Traganos, F.7
-
66
-
-
0027432452
-
The sensitivity to DNA topoisomerase inhibitors in L5178Y lymphoma strains is not related to a primary defect of DNA topoisomerases
-
Lanza, A., Tornaletti, S., Stefanini, M., Evans, H. H., Ricanati, M., Astaldi-Ricotti, J., and Pedrini, A. M. The sensitivity to DNA topoisomerase inhibitors in L5178Y lymphoma strains is not related to a primary defect of DNA topoisomerases. Carcinogenesis (Lond.), 14: 1759–1763, 1993.
-
(1993)
Carcinogenesis (Lond.)
, vol.14
, pp. 1759-1763
-
-
Lanza, A.1
Tornaletti, S.2
Stefanini, M.3
Evans, H.H.4
Ricanati, M.5
Astaldi-Ricotti, J.6
Pedrini, A.M.7
-
67
-
-
0028291878
-
Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells
-
Ryan, A. J., Squires, S., Strutt, H. L., Evans, A., and Johnson, R. T. Different fates of camptothecin-induced replication fork-associated double-strand DNA breaks in mammalian cells. Carcinogenesis (Lond.), 15: 823–828, 1994.
-
(1994)
Carcinogenesis (Lond.)
, vol.15
, pp. 823-828
-
-
Ryan, A.J.1
Squires, S.2
Strutt, H.L.3
Evans, A.4
Johnson, R.T.5
-
68
-
-
0028345613
-
Cell cycle control and cancer chemotherapy
-
Kohn, K. W., Jackman, J., and O'Connor, P. M. Cell cycle control and cancer chemotherapy. J. Cell. Biochem., 54: 440–452, 1994.
-
(1994)
J. Cell. Biochem.
, vol.54
, pp. 440-452
-
-
Kohn, K.W.1
Jackman, J.2
O'Connor, P.M.3
-
69
-
-
0024590823
-
Enhanced sensitivity to camptothecin in ataxia telangiectasia cells and its relationship with the expression of DNA topoisomerase I
-
Smith, P. J., Makinson, T. A., and Watson, J. V. Enhanced sensitivity to camptothecin in ataxia telangiectasia cells and its relationship with the expression of DNA topoisomerase I. Int. J. Radiat. Biol., 55: 217–231, 1989.
-
(1989)
Int. J. Radiat. Biol.
, vol.55
, pp. 217-231
-
-
Smith, P.J.1
Makinson, T.A.2
Watson, J.V.3
-
70
-
-
0027173884
-
Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA
-
Squires, S., Ryan, A. J., Strutt, H. L., and Johnson, R. T. Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA. Cancer Res., 53: 2012–2019, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2012-2019
-
-
Squires, S.1
Ryan, A.J.2
Strutt, H.L.3
Johnson, R.T.4
-
71
-
-
0025696390
-
Hypersensitivity to clinically useful alkylating agents and radiation in poly(ADP-ribose) polymerase-deficient cell lines
-
Chatterjee, S., Cheng, M. F., and Berger, N. A. Hypersensitivity to clinically useful alkylating agents and radiation in poly(ADP-ribose) polymerase-deficient cell lines. Cancer Commun., 2: 401–407, 1990.
-
(1990)
Cancer Commun.
, vol.2
, pp. 401-407
-
-
Chatterjee, S.1
Cheng, M.F.2
Berger, N.A.3
-
72
-
-
0026625512
-
The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B
-
Tsao, Y-P., D'Arpa, P., and Liu, L. F. The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B. Cancer Res., 52: 1823–1829, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1823-1829
-
-
Tsao, Y.-P.1
D'Arpa, P.2
Liu, L.F.3
-
73
-
-
0028873880
-
Unscheduled activation of cyclin Bl/cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage
-
Shimizu, T., O'Connor, P. M., Kohn, K. W., and Pommier, Y. Unscheduled activation of cyclin Bl/cdc2 kinase in human promyelocytic leukemia cell line HL60 cells undergoing apoptosis induced by DNA damage. Cancer Res., 55: 228–231, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 228-231
-
-
Shimizu, T.1
O'Connor, P.M.2
Kohn, K.W.3
Pommier, Y.4
-
74
-
-
0027978970
-
Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines
-
Gong, J., Ardelt, B., Traganos, F., and Darzynkiewicz, Z. Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. Cancer Res., 54: 4285–4288, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4285-4288
-
-
Gong, J.1
Ardelt, B.2
Traganos, F.3
Darzynkiewicz, Z.4
-
75
-
-
0028001422
-
Cell cycle control processes determine cytostasis or cytotoxicity in thymineless death of colon cancer cells
-
Houghton, J. A., Harwood, F. G., and Houghton, P. J. Cell cycle control processes determine cytostasis or cytotoxicity in thymineless death of colon cancer cells. Cancer Res., 54: 4967–4973, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4967-4973
-
-
Houghton, J.A.1
Harwood, F.G.2
Houghton, P.J.3
-
76
-
-
9244245112
-
Drug resistance
-
M. C. Perry (ed.), Baltimore, MD: Williams & Wilkins
-
Goldie, J. H. Drug resistance. In: M. C. Perry (ed.), The Chemotherapy Source Book, pp. 54–66. Baltimore, MD: Williams & Wilkins, 1992.
-
(1992)
The Chemotherapy Source Book
, pp. 54-66
-
-
Goldie, J.H.1
-
77
-
-
0001773293
-
-
The Anticancer Drugs, Ed. 2, New York: Oxford University Press
-
Pratt, W. B., Ruddon, R. W., Ensminger, W. D., and Maybaum, J. Resistance to anticancer drugs. In: The Anticancer Drugs, Ed. 2, pp. 50–66. New York: Oxford University Press, 1994.
-
(1994)
Resistance to anticancer drugs
, pp. 50-66
-
-
Pratt, W.B.1
Ruddon, R.W.2
Ensminger, W.D.3
Maybaum, J.4
-
78
-
-
0024229066
-
Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin
-
Eng, W. K., Faucette, L., Johnson, R. K., and Sternglanz, R. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. Mol. Pharmacol., 34: 755–760, 1989.
-
(1989)
Mol. Pharmacol.
, vol.34
, pp. 755-760
-
-
Eng, W.K.1
Faucette, L.2
Johnson, R.K.3
Sternglanz, R.4
-
79
-
-
0026742287
-
Characterization of camptothecin-resistant Chinese hamster lung cells
-
Chang, J-Y., Dethlefsen, L. A., Barley, L. R., Zhou, B. S., and Cheng, Y-C. Characterization of camptothecin-resistant Chinese hamster lung cells. Biochem. Pharmacol., 43: 2443–2452, 1992.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2443-2452
-
-
Chang, J.-Y.1
Dethlefsen, L.A.2
Barley, L.R.3
Zhou, B.S.4
Cheng, Y.-C.5
-
80
-
-
0025151823
-
Decreased expression of topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody
-
Sugimoto, Y., Tsukahara, S., Oh-Hara, T., Isoe, T., and Tsunio, T. Decreased expression of topoisomerase I in camptothecin-resistant tumor cell lines as determined by a monoclonal antibody. Cancer Res., 50: 6925–6930, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 6925-6930
-
-
Sugimoto, Y.1
Tsukahara, S.2
Oh-Hara, T.3
Isoe, T.4
Tsunio, T.5
-
81
-
-
0025115965
-
Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content
-
Eng, W. K., McCabe, F. L., Tan, K. B., Mattern, M. R., Hofmann, G. A., Woessner, R. D., Hertzberg, R. P., and Johnson, R. K. Development of a stable camptothecin-resistant subline of P388 leukemia with reduced topoisomerase I content. Mol. Pharmacol., 38: 471–480, 1990.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 471-480
-
-
Eng, W.K.1
McCabe, F.L.2
Tan, K.B.3
Mattern, M.R.4
Hofmann, G.A.5
Woessner, R.D.6
Hertzberg, R.P.7
Johnson, R.K.8
-
82
-
-
0023873933
-
Characterization of a camptothecin-resistant human DNA topoisomerase
-
Kjeldsen, E., Bonven, B., Andoh, T., Ishii, K., Okada, K., Bolund, L., and Westergaard, O. Characterization of a camptothecin-resistant human DNA topoisomerase. J. Biol. Chem., 263: 3912–3916, 1988.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3912-3916
-
-
Kjeldsen, E.1
Bonven, B.2
Andoh, T.3
Ishii, K.4
Okada, K.5
Bolund, L.6
Westergaard, O.7
-
83
-
-
0026694495
-
Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture
-
Tanizawa, A., and Pommier, Y. Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture. Cancer Res., 52: 1848–1854, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1848-1854
-
-
Tanizawa, A.1
Pommier, Y.2
-
84
-
-
0027472338
-
Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation
-
Madelaine, I., Prost, S., Naudin, A., Riou, G., Lavelle, F., and Riou, J-F. Sequential modifications of topoisomerase I activity in a camptothecin-resistant cell line established by progressive adaptation. Biochem. Pharmacol., 45: 339–348, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 339-348
-
-
Madelaine, I.1
Prost, S.2
Naudin, A.3
Riou, G.4
Lavelle, F.5
Riou, J.-F.6
-
85
-
-
0027238539
-
Characterization of an altered DNA catalysis of camptothecin-resistant eukaryotic topoisomerase I
-
Gromova, I. I., Kjeldsen, E., Svejstrup, J. Q., Alsner, J., Christiansen, K., and Westergaard, O. Characterization of an altered DNA catalysis of camptothecin-resistant eukaryotic topoisomerase I. Nucleic Acids Res., 21: 593–600, 1993.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 593-600
-
-
Gromova, I.I.1
Kjeldsen, E.2
Svejstrup, J.Q.3
Alsner, J.4
Christiansen, K.5
Westergaard, O.6
-
86
-
-
0028030721
-
Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitrocamptothecin
-
Rubin, E., Pantazis, P., Bharti, T., Toppmeyer, D., Giovanella, B. C., and Kufe, D. Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitrocamptothecin. J. Biol. Chem., 269: 2433–2439, 1994
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2433-2439
-
-
Rubin, E.1
Pantazis, P.2
Bharti, T.3
Toppmeyer, D.4
Giovanella, B.C.5
Kufe, D.6
-
87
-
-
0028169367
-
Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitro-camptothecin
-
Pantazis, P., Mendoza, J. T., DeJesus, A., Rubin, E., Kufe, D., and Giovanella, B. C. Partial characterization of human leukemia U-937 cell sublines resistant to 9-nitro-camptothecin. Eur. J. Haematol., 53: 135–144, 1994.
-
(1994)
Eur. J. Haematol.
, vol.53
, pp. 135-144
-
-
Pantazis, P.1
Mendoza, J.T.2
DeJesus, A.3
Rubin, E.4
Kufe, D.5
Giovanella, B.C.6
-
88
-
-
0022833525
-
Multidrug resistance
-
Gerlach, J. H., Kartner, N., Bell, D. R., and Ling, V. Multidrug resistance. Cancer Surv., 5: 25–46, 1986.
-
(1986)
Cancer Surv.
, vol.5
, pp. 25-46
-
-
Gerlach, J.H.1
Kartner, N.2
Bell, D.R.3
Ling, V.4
-
89
-
-
0024329881
-
The biochemistry of P-glycoprotein-mediated multidrug resistance
-
Endicott, J. A., and Ling, V. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem., 58: 137–171, 1989.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
90
-
-
0028269030
-
Clinical relevance of P-glycoprotein expression in haematological malignancies
-
Nooter, K., and Sonneveld, P. Clinical relevance of P-glycoprotein expression in haematological malignancies. Leuk. Res., 18: 233–243, 1994.
-
(1994)
Leuk. Res.
, vol.18
, pp. 233-243
-
-
Nooter, K.1
Sonneveld, P.2
-
91
-
-
0005313137
-
Combination chemotherapy
-
M. C. Perry (ed.), Baltimore, MD: Williams & Wilkins
-
Friedland, M. L. Combination chemotherapy. In: M. C. Perry (ed.), The Chemotherapy Source Book, pp. 90–95. Baltimore, MD: Williams & Wilkins, 1992.
-
(1992)
The Chemotherapy Source Book
, pp. 90-95
-
-
Friedland, M.L.1
-
92
-
-
0002611557
-
Choice of drugs for cancer chemotherapy
-
The Anticancer Drugs, Ed. 2, New York: Oxford University Press
-
Pratt, W. B., Ruddon, R. W., Ensminger, W. D., and Maybaum, J. Choice of drugs for cancer chemotherapy. In: The Anticancer Drugs, Ed. 2, pp. 235–246. New York: Oxford University Press, 1994.
-
(1994)
, pp. 235-246
-
-
Pratt, W.B.1
Ruddon, R.W.2
Ensminger, W.D.3
Maybaum, J.4
-
93
-
-
0025893984
-
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line
-
Kaufmann, S. H. Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line. Cancer Res., 57: 1129–1136, 1991.
-
(1991)
Cancer Res.
, vol.57
, pp. 1129-1136
-
-
Kaufmann, S.H.1
-
94
-
-
0026594602
-
Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT-29 cells
-
Bertrand, R., O'Conner, P. M., Kerrigan, D., and Pommier, Y. Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT-29 cells. Eur. J. Cancer, 28A: 743–748, 1992.
-
(1992)
Eur. J. Cancer
, vol.28A
, pp. 743-748
-
-
Bertrand, R.1
O'Conner, P.M.2
Kerrigan, D.3
Pommier, Y.4
-
95
-
-
0027396118
-
Inhibition of DNA synthesis and DNA fragmentation in stimulated splenocytes by the concerted action of topoisomerase I and II poisons
-
Taudou, G., Portemer, C, Jaxel, C, and Duguet, M. Inhibition of DNA synthesis and DNA fragmentation in stimulated splenocytes by the concerted action of topoisomerase I and II poisons. Biochem. Pharmacol., 45: 331–337, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 331-337
-
-
Taudou, G.1
Portemer, C.2
Jaxel, C.3
Duguet, M.4
-
96
-
-
0028000917
-
Development of resistance to 9-nitro-camptothecin by human leukemia U-937 cells in vitro correlates with altered sensitivities to several anticancer drugs
-
Pantazis, P., Mendoza, J., DeJesus, A., Early, J., Shaw, M., and Giovanella, B. Development of resistance to 9-nitro-camptothecin by human leukemia U-937 cells in vitro correlates with altered sensitivities to several anticancer drugs. Anticancer Drugs, 5: 473–479, 1994.
-
(1994)
Anticancer Drugs
, vol.5
, pp. 473-479
-
-
Pantazis, P.1
Mendoza, J.2
DeJesus, A.3
Early, J.4
Shaw, M.5
Giovanella, B.6
-
97
-
-
0028796774
-
Sensitivity of camptothecin-resistant human leukemia cells and tumors to anticancer drugs with diverse mechanisms of action
-
Pantazis, P., Vardeman, D., Mendoza, J., Early, J., Kozielski, A., DeJesus, A., and Giovanella, B. Sensitivity of camptothecin-resistant human leukemia cells and tumors to anticancer drugs with diverse mechanisms of action. Leuk. Res., 19: 45–55, 1995.
-
(1995)
Leuk. Res.
, vol.19
, pp. 45-55
-
-
Pantazis, P.1
Vardeman, D.2
Mendoza, J.3
Early, J.4
Kozielski, A.5
DeJesus, A.6
Giovanella, B.7
-
98
-
-
0024398044
-
Unknotting the complexities of multidrug resistance: the involvement of DNA topoisomerases in drug action and resistance
-
Beck, W. T. Unknotting the complexities of multidrug resistance: the involvement of DNA topoisomerases in drug action and resistance. J. Natl. Cancer Inst., 81: 1683–1685, 1989.
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 1683-1685
-
-
Beck, W.T.1
-
99
-
-
0024318022
-
Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors
-
Tan, K. B., Mattern, M. R., Eng, W-K., McCabe, F. L., and Johnson, R. K. Nonproductive rearrangement of DNA topoisomerase I and II genes: correlation with resistance to topoisomerase inhibitors. J. Natl. Cancer. Inst., 81: 1732–1735, 1989.
-
(1989)
J. Natl. Cancer. Inst.
, vol.81
, pp. 1732-1735
-
-
Tan, K.B.1
Mattern, M.R.2
Eng, W.-K.3
McCabe, F.L.4
Johnson, R.K.5
-
100
-
-
0025686125
-
Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines
-
Sugimoto, Y., Tsukahara, S., Oh-Hara, T., Liu, L. F., and Tsuruo, T. Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines. Cancer Res., 50: 7962–7965, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 7962-7965
-
-
Sugimoto, Y.1
Tsukahara, S.2
Oh-Hara, T.3
Liu, L.F.4
Tsuruo, T.5
-
101
-
-
0024309873
-
P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines
-
Bradley, G., Naik, M., and Ling, V. P-glycoprotein expression in multidrug-resistant human ovarian carcinoma cell lines. Cancer Res., 49: 2790–2796, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 2790-2796
-
-
Bradley, G.1
Naik, M.2
Ling, V.3
-
102
-
-
0026547001
-
Biochemical and genetic characterization of the multidrug resistance phenotype in murine macrophage-like J774.2 cells
-
Kirschner, L. S., Greenberger, L. M., Hsu, S. I-H., Yang, C-P. H., Cohen, D., Piekarz, R. L., Castillo, G., Han, E. K-H., Yu, L., and Horwitz, S. B. Biochemical and genetic characterization of the multidrug resistance phenotype in murine macrophage-like J774.2 cells. Biochem. Pharmacol., 43: 77–87, 1992.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 77-87
-
-
Kirschner, L.S.1
Greenberger, L.M.2
Hsu, S.I-H.3
Yang, C-P. H.4
Cohen, D.5
Piekarz, R.L.6
Castillo, G.7
Han, E.K-H.8
Yu, L.9
Horwitz, S.B.10
-
103
-
-
84965818548
-
Isolation of amplified and overexpressed DNA sequences from Adriamycin-resistant human breast cancer cells
-
Fairchild, C. R., Ivy, S. P., Kao-Shan, C-S., Whang-Peng, J., Rosen, N., Israel, M. A., Melera, P. W., Cowan, K. H., and Goldsmith, M. E. Isolation of amplified and overexpressed DNA sequences from Adriamycin-resistant human breast cancer cells. Cancer Res., 47: 5141–5148, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 5141-5148
-
-
Fairchild, C.R.1
Ivy, S.P.2
Kao-Shan, C.-S.3
Whang-Peng, J.4
Rosen, N.5
Israel, M.A.6
Melera, P.W.7
Cowan, K.H.8
Goldsmith, M.E.9
-
104
-
-
0024798332
-
Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomersase II-mediated DNA cleavage
-
Ganapathi, R., Grabowski, D., Ford, J., Heiss, C, Kerrigan, D., and Pommier, Y. Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomersase II-mediated DNA cleavage. Cancer Commun., 1: 217–224, 1989.
-
(1989)
Cancer Commun.
, vol.1
, pp. 217-224
-
-
Ganapathi, R.1
Grabowski, D.2
Ford, J.3
Heiss, C.4
Kerrigan, D.5
Pommier, Y.6
-
105
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole, S. P. C., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C., Stewart, A. J., Kurz, E. U., Dunkan, A. M. V., and Deeley, R. G. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (Washington DC), 258: 1650–1654, 1992.
-
(1992)
Science (Washington DC)
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Dunkan, A.M.V.9
Deeley, R.G.10
-
106
-
-
0028009810
-
Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance
-
Schneider, E., Horton, J. K., Yang, C-H., Nakagawa, M., and Cowan, K. H. Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Cancer Res., 54: 152–158, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 152-158
-
-
Schneider, E.1
Horton, J.K.2
Yang, C.-H.3
Nakagawa, M.4
Cowan, K.H.5
-
107
-
-
0028054888
-
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs
-
Grant, C. E., Valdimarsson, G., Hipfner, D. R., Amquist, K. C., Cole, S. P. C., and Deeley, R. G. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res., 54: 357–361, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 357-361
-
-
Grant, C.E.1
Valdimarsson, G.2
Hipfner, D.R.3
Amquist, K.C.4
Cole, S.5
Deeley, R.G.6
-
108
-
-
0028268620
-
Expression of complementary DNA library transfer establishes mrp as a multidrug resistance gene
-
Kruh, G. D., Chan, A., Myers, K., Gaughan, K., Miki, T., and Aaronson, S. A. Expression of complementary DNA library transfer establishes mrp as a multidrug resistance gene. Cancer Res., 54: 1649–1652, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1649-1652
-
-
Kruh, G.D.1
Chan, A.2
Myers, K.3
Gaughan, K.4
Miki, T.5
Aaronson, S.A.6
-
109
-
-
0028081258
-
Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells
-
Slapak, C. A., Mizunuma, N., and Kufe, D. W. Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemia cells. Blood, 84: 3113–3121, 1994.
-
(1994)
Blood
, vol.84
, pp. 3113-3121
-
-
Slapak, C.A.1
Mizunuma, N.2
Kufe, D.W.3
-
110
-
-
0028080927
-
Overexpression of the multidrug resistance-associated protein gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells
-
Slapak, C. A., Fracasso, P. M., Martell, R. L., Toppmeyer, D. L., Lecerf, J-M., and Levy, S. B. Overexpression of the multidrug resistance-associated protein gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells. Cancer Res., 54: 5607–5613, 1994
-
(1994)
Cancer Res.
, vol.54
, pp. 5607-5613
-
-
Slapak, C.A.1
Fracasso, P.M.2
Martell, R.L.3
Toppmeyer, D.L.4
Lecerf, J.-M.5
Levy, S.B.6
-
111
-
-
0027172915
-
Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines
-
Zaman, G. J. R., Versantvoort, C. H. M., Smit, J. J. M., Eijdems, E. W. H. M., de Haas, M., Smith, A. J., Broxterman, H. J., Mulder, N. H., de Vries, E. G. E., Baas, F., and Borst, P. Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines. Cancer Res., 53: 1747–1750, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 1747-1750
-
-
Zaman, G.J.R.1
Versantvoort, C.H.M.2
Smit, J.J.M.3
Eijdems, E.W.H.M.4
de Haas, M.5
Smith, A.J.6
Broxterman, H.J.7
Mulder, N.H.8
de Vries, E.G.E.9
Baas, F.10
Borst, P.11
-
112
-
-
0026339352
-
Camptothecin overcomes MDRI -mediated resistance in human KB carcinoma cells
-
Chen, A. Y., Potmesil, M., Wall, M. E., Wani, M. C., and Liu, L. F. Camptothecin overcomes MDRI -mediated resistance in human KB carcinoma cells. Cancer Res., 51: 6039–6044, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6039-6044
-
-
Chen, A.Y.1
Potmesil, M.2
Wall, M.E.3
Wani, M.C.4
Liu, L.F.5
-
113
-
-
0343911435
-
Combined modality therapy
-
M. C. Perry, (ed.), Baltimore, MD: Williams & Wilkins
-
Raefsky, E. L., and Wasserman, T. H. Combined modality therapy. In: M. C. Perry, (ed.), The Chemotherapy Source Book, pp. 110–129. Baltimore, MD: Williams & Wilkins, 1992.
-
(1992)
The Chemotherapy Source Book
, pp. 110-129
-
-
Raefsky, E.L.1
Wasserman, T.H.2
-
114
-
-
84969079803
-
-
(eds.), Tucson, AZ
-
In: E. W. Gerner and T. C. Cetas (eds.), Hyperthermic Oncology 1992, Proceedings of the 6th International Congress on Hyperthermic Oncology, Vol. 2. Tucson, AZ: 1993.
-
(1993)
Hyperthermic Oncology 1992, Proceedings of the 6th International Congress on Hyperthermic Oncology
, vol.2
-
-
Gerner, E.W.1
Cetas, T.C.2
-
115
-
-
0343029622
-
Thermal enhancement of the actions of anticancer agents
-
G. M. Hahn (ed.), New York: Plenum Publishing Corp.
-
Hahn, G. M. Thermal enhancement of the actions of anticancer agents. In: G. M. Hahn (ed.), Hyperthermia and Cancer, pp. 55–86. New York: Plenum Publishing Corp., 1982.
-
(1982)
Hyperthermia and Cancer
, pp. 55-86
-
-
Hahn, G.M.1
-
116
-
-
0025148702
-
The inhibition of cellular recovery in human tumor cells by inhibitors of topoisomerase I
-
Musk, S. R. R., and Steel, G. G. The inhibition of cellular recovery in human tumor cells by inhibitors of topoisomerase I. Br. J. Cancer, 62: 364–367, 1990.
-
(1990)
Br. J. Cancer
, vol.62
, pp. 364-367
-
-
Musk, S.R.R.1
Steel, G.G.2
-
117
-
-
0026441127
-
Posttreatment exposure to camptothecin unbalances the lethal effects of X-rays on radioresistant malignant melanoma cells
-
Boothman, D. A., Wang, M., Schea, R. A., Burrows, H. L., Strickfaden, S., and Owens, J. K. Posttreatment exposure to camptothecin unbalances the lethal effects of X-rays on radioresistant malignant melanoma cells. Int. J. Radiat. Oncol. Biol. Phys., 24: 939–948, 1992.
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.24
, pp. 939-948
-
-
Boothman, D.A.1
Wang, M.2
Schea, R.A.3
Burrows, H.L.4
Strickfaden, S.5
Owens, J.K.6
-
118
-
-
0027529978
-
Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum (II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo
-
Boscia, R. E., Korbut, T., Holden, S. A., Ara, G., and Teicher, B. A. Interaction of topoisomerase I inhibitors with radiation in cis-diamminedichloroplatinum (II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo. Int. J. Cancer, 53: 118–123, 1993.
-
(1993)
Int. J. Cancer
, vol.53
, pp. 118-123
-
-
Boscia, R.E.1
Korbut, T.2
Holden, S.A.3
Ara, G.4
Teicher, B.A.5
-
119
-
-
0026659048
-
DNA damaging and cell cycle effects of the topoisomerase I poison camptothecin in irradiated human cells
-
Falk, S. J., and Smith, P. J. DNA damaging and cell cycle effects of the topoisomerase I poison camptothecin in irradiated human cells. Int. J. Radiat. Biol., 61: 749–757, 1992.
-
(1992)
Int. J. Radiat. Biol.
, vol.61
, pp. 749-757
-
-
Falk, S.J.1
Smith, P.2
-
120
-
-
0026489662
-
Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation. Cell
-
Del Bino, G., Bruno, S., Yi, P. N., and Darzynkiewicz, Z. Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation. Cell. Prolif., 25: 537–548, 1992.
-
(1992)
Prolif.
, vol.25
, pp. 537-548
-
-
Del Bino, G.1
Bruno, S.2
Yi, P.N.3
Darzynkiewicz, Z.4
-
121
-
-
0027261147
-
The cell cycle related differences in susceptibility of HL-60 cells
-
Gorczyca, W., Gong, J., Ardelt, B., Traganos, F., and Darzynkiewicz, Z. The cell cycle related differences in susceptibility of HL-60 cells. Cancer Res., 53: 3186–3192, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3186-3192
-
-
Gorczyca, W.1
Gong, J.2
Ardelt, B.3
Traganos, F.4
Darzynkiewicz, Z.5
-
122
-
-
0028328850
-
Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells
-
Hennequin, C, Giocanti, N., Balosso, J., and Favaudon, Y. Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells. Cancer Res., 54: 1720–1728, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1720-1728
-
-
Hennequin, C.1
Giocanti, N.2
Balosso, J.3
Favaudon, Y.4
-
123
-
-
0028094758
-
Down-regulation of topoisomerase I in mammalian cells following ionizing radiation
-
Boothman, D. A., Fukunaga, N., and Wang, M. Down-regulation of topoisomerase I in mammalian cells following ionizing radiation. Cancer Res., 54: 4618–4626, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4618-4626
-
-
Boothman, D.A.1
Fukunaga, N.2
Wang, M.3
-
124
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan, M. B., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R. W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res., 51: 6304–6311, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
125
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz, S. J., Plunkett, B. S., Walsh, W. W., and Kastan, M. D. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491–7495, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.W.3
Kastan, M.D.4
-
126
-
-
0027029077
-
A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells? Semin
-
O'Connor, P. M., and Kohn, K. W. A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells? Semin. Cancer Biol., 3: 409–416, 1992.
-
(1992)
Cancer Biol.
, vol.3
, pp. 409-416
-
-
O'Connor, P.M.1
Kohn, K.W.2
-
127
-
-
0027421045
-
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
-
O'Connor, P. M., Jackman, J., Jondle, D., Bhatia, K., Magrath, I., and Kohn, K. W. Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res., 53: 4776–4780, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4776-4780
-
-
O'Connor, P.M.1
Jackman, J.2
Jondle, D.3
Bhatia, K.4
Magrath, I.5
Kohn, K.W.6
-
128
-
-
0027285380
-
p53 mutations increase resistance to ionizing radiation
-
Lee, J. M., and Bernstein, A. p53 mutations increase resistance to ionizing radiation. Proc. Natl. Acad. Sci. USA, 90: 5742–5746, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5742-5746
-
-
Lee, J.M.1
Bernstein, A.2
-
129
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity
-
McIlwrath, A. J., Vasey, P. A., Ross, G. M., and Brown, R. Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res., 54: 3718–3722, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
130
-
-
0010352059
-
Demonstration of the greater susceptibility to heat of sarcoma cells
-
Lambert, R. A. Demonstration of the greater susceptibility to heat of sarcoma cells. J. Am. Med. Assoc., 59: 2147–2148, 1912.
-
(1912)
J. Am. Med. Assoc.
, vol.59
, pp. 2147-2148
-
-
Lambert, R.A.1
-
131
-
-
0018867076
-
Correlation of the thermosensitivity of cells to their malignant potential
-
Giovanella, B. C., Stehlin, J. S., and Yim, S. O. Correlation of the thermosensitivity of cells to their malignant potential. Ann. NY Acad. Sci., 335: 206–214, 1980.
-
(1980)
Ann. NY Acad. Sci.
, vol.335
, pp. 206-214
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Yim, S.O.3
-
132
-
-
0020412931
-
Enhancement of cis-platinum(II) diamminedichloride cytotoxicity by hyperthermia
-
Fisher, G. A., and Hahn, G. M. Enhancement of cis-platinum(II) diamminedichloride cytotoxicity by hyperthermia. Natl. Cancer Inst. Mongr., 61: 255–257, 1982.
-
(1982)
Natl. Cancer Inst. Mongr.
, vol.61
, pp. 255-257
-
-
Fisher, G.A.1
Hahn, G.M.2
-
133
-
-
84965835300
-
Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia
-
Watanabe, N., Niitsu, Y., Umeno, H., Sone, H., Neda, H., Yamauchi, N., Maeda, M, and Urushizaki, I. Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia. Cancer Res., 48: 650–653, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 650-653
-
-
Watanabe, N.1
Niitsu, Y.2
Umeno, H.3
Sone, H.4
Neda, H.5
Yamauchi, N.6
Maeda, M.7
Urushizaki, I.8
-
134
-
-
84965832464
-
Synergistic effects of recombinant human tumor necrosis factor and hyperthermia on in vitro cytotoxicity and artificial metastasis
-
Niitsu, Y., Watanabe, N., Umeno, H., Sone, H., Neda, H., Yamauchi, N., Maeda, M., and Urushizaki, I. Synergistic effects of recombinant human tumor necrosis factor and hyperthermia on in vitro cytotoxicity and artificial metastasis. Cancer Res., 48: 654–657, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 654-657
-
-
Niitsu, Y.1
Watanabe, N.2
Umeno, H.3
Sone, H.4
Neda, H.5
Yamauchi, N.6
Maeda, M.7
Urushizaki, I.8
-
135
-
-
0024320045
-
Neutral red uptake and clonogenic survival assays of the hyperthermia sensitization of tumor cells to tumor necrosis factor
-
Tomasovic, S. P., Barta, M., and Klostergaard, J. Neutral red uptake and clonogenic survival assays of the hyperthermia sensitization of tumor cells to tumor necrosis factor. Radiat. Res., 119: 325–337, 1989.
-
(1989)
Radiat. Res.
, vol.119
, pp. 325-337
-
-
Tomasovic, S.P.1
Barta, M.2
Klostergaard, J.3
-
136
-
-
0025911033
-
Augmented antitumor effects of combined treatment with hyperthermia and tumor necrosis factor on human gastric cancer xenotransplanted into nude mice
-
Fujimoto, S., Konno, O., Kobayashi, K., Kokubun, M., Shrestha, R. D., Kiuchi, S., Takahashi, M., Ohta, M., and Okui, K. Augmented antitumor effects of combined treatment with hyperthermia and tumor necrosis factor on human gastric cancer xenotransplanted into nude mice. Int. J. Hyperthermia, 7: 511–518, 1991.
-
(1991)
Int. J. Hyperthermia
, vol.7
, pp. 511-518
-
-
Fujimoto, S.1
Konno, O.2
Kobayashi, K.3
Kokubun, M.4
Shrestha, R.D.5
Kiuchi, S.6
Takahashi, M.7
Ohta, M.8
Okui, K.9
-
137
-
-
0024521706
-
Tumoricidal interactions of hyperthermia with carboplatin, cisplatin and etoposide
-
Cohen, J. D., Robins, H. I., and Schmitt, C. L. Tumoricidal interactions of hyperthermia with carboplatin, cisplatin and etoposide. Cancer Lett., 44: 205–210, 1989.
-
(1989)
Cancer Lett.
, vol.44
, pp. 205-210
-
-
Cohen, J.D.1
Robins, H.I.2
Schmitt, C.L.3
-
138
-
-
0024539361
-
Reduced DNA break formation and cytotoxicity of the topoisomerase II drug 4′-(9′-acridinylamino)methanesulfon-m-anisidide when combined with hyperthermia in human and rodent cell lines
-
Kampinga, H. H., Kruk, G. V. D., and Konings, A. W. T. Reduced DNA break formation and cytotoxicity of the topoisomerase II drug 4′-(9′-acridinylamino)methanesulfon-m-anisidide when combined with hyperthermia in human and rodent cell lines. Cancer Res., 49: 1712–1717, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 1712-1717
-
-
Kampinga, H.H.1
Kruk, G.V.D.2
Konings, A.W.T.3
-
139
-
-
0027957138
-
Hyperthermia can reduce cytotoxicity from etoposide without a corresponding reduction in the number of topoisomerase II-DNA cleavable complexes
-
Dynlacht, J. R., Wong, R. S. L., Albright, N., and Dewey, W. C. Hyperthermia can reduce cytotoxicity from etoposide without a corresponding reduction in the number of topoisomerase II-DNA cleavable complexes. Cancer Res., 54: 4129–4137, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4129-4137
-
-
Dynlacht, J.R.1
Wong, R.S.L.2
Albright, N.3
Dewey, W.C.4
-
140
-
-
0027220258
-
Addition of a topoisomerase I inhibitor to trimodality therapy [cis-diaminedichloro-platinum(II)/heat/radiation] in a murine tumor
-
Teicher, B. A., Holden, S. A., Khandakar, V., and Herman, T. S. Addition of a topoisomerase I inhibitor to trimodality therapy [cis-diaminedichloro-platinum(II)/heat/radiation] in a murine tumor. J. Cancer Res. Clin. Oncol., 119: 645–651, 1993.
-
(1993)
J. Cancer Res. Clin. Oncol.
, vol.119
, pp. 645-651
-
-
Teicher, B.A.1
Holden, S.A.2
Khandakar, V.3
Herman, T.S.4
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