Overexpression of the XPA Repair Gene Increases Resistance to Ultraviolet Radiation in Human Cells by Selective Repair of DNA Damage

Cancer Research

Volumn 55, Issue 24, 1995, Pages 6152-6160

  Cleaver, James E ^a   Charles, Wayne C ^a   McDowell, Mindy L ^a   Sadinski, Walt J ^a   Mitchell, David L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ARTICLE; CANCER SUSCEPTIBILITY; CELL SURVIVAL; CHROMOSOME 9Q; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RADIOSENSITIVITY; ULTRAVIOLET RADIATION; VIRUS GENOME;

CELLS, CULTURED; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENE EXPRESSION; HUMAN; RECOMBINANT PROTEINS; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 0028822646     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Cleaver, J. E. It was a very good year for DNA repair. Cell, 76: 1–4, 1994.
2. Aboussekhra, A., Biggerstaff, M., Shivji, M. K. K., Vilpo, J. A., Moncollin, V., Podust, V. N., Protic, M., Hubscher, U., Egly, J-M., and Wood, R. D. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell, 80: 859–868, 1995.
3. Wei, Q., Matanoski. G. M., Farmer, E. R., Hedayati, M. A., and Grossman, L. DNA repair and aging in basal cell carcinoma: a molecular epidemiology study. Proc. Natl. Acad. Sci. USA, 90: 1614–1618, 1993.
4. Wei, Q., Matanoski, G. M., Farmer, E. R., Hedayati, M. A., and Grossman, L. DNA repair related to multiple skin cancers and drug use. Cancer Res., 54: 437–440, 1994.
5. Painter, R. B., and Cleaver, J. E. Repair replication, unscheduled DNA synthesis, and the repair of mammalian DNA. Radiat. Res., 37: 451–466, 1969.
6. Tanaka, K., Miura, N., Satokata, I., Miyamoto, I., Yoshida, M. C., Satoh, Y., Kondo, S., Yasui, A., Okayama, H., and Okada, Y. Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Nature (Lond.), 348: 73–76, 1990.
7. Jones, C. J., and Wood, R. D. Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA. Biochemistry, 32: 12096–12104, 1993.
8. Cleaver, J. E., and Kraemer, K. H. Xeroderma pigmentosum. In: C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle (eds.). The Metabolic Bases of Inherited Disease, Ed. 7, Vol. 3, pp. 4393–4419. New York: McGraw-Hill, Inc., 1995.
9. McDowell, M. L., Nguyen, T., and Cleaver, J. E. A single-site mutation in the XPAC gene alters photoproduct recognition. Mutagenesis, 8: 155–161, 1993.
10. Cleaver, J. E., Cortes, F., Lutze, L. H., Morgan, W. F., Player, A. N., and Mitchell, D. L. Unique DNA repair properties of a xeroderma pigmentosum revenant. Mol. Cell. Biol., 7: 3353–3357, 1987.
11. Lommel, L., and Hanawalt, P. C. Increased UV resistance of a xeroderma pigmentosum revenant cell line is correlated with selective repair of the transcribed strand of an expressed gene. Mol. Cell. Biol., 13: 970–976, 1993.
12. Mori, T., Rinaldy, T. L., Athwal, R. S., Kaur, G. P., Nikaido, O., Lloyd, R. S., and Rinaldy, A. A xeroderma pigmentosum complementation group A related gene: confirmation using monoclonal antibodies against the cyclobutane dimer and (6–4) photoproduct. Mutat. Res., 293: 143–150, 1993.
13. Kaur, G. P., Rinaldy, A., Lloyd, R. S., and Athwal, R. S. A gene that partially complements xeroderma pigmentosum group A cells maps to human chromosome 8. Somatic Cell Mol. Genet., 18: 371–379, 1992.
14. Rinaldy, A., Bellew, T., Egli, E., and Lloyd, R. S. Increased UV resistance in xeroderma pigmentosum group A cells after transformation with a human genomic DNA clone. Proc. Natl. Acad. Sci. USA, 87: 6818–6822, 1990.
15. Cleaver, J. E., and Thomas, G. H. Rapid diagnosis of sensitivity to ultraviolet light in fibroblasts from dermatologie disorders, with particular reference to xeroderma pigmentosum. J. Invest. Dermatol., 90: 467–471, 1988.
16. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294–5299, 1979.
17. Mitchell, D. L., Haipek, C. A., and Clarkson, J. M. (6–4) Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers. Mutat. Res., 143: 109–112, 1985.
18. Mitchell, D. L., Haipek, C. A., and Clarkson, J. M. Further characterization of a polyclonal antiserum for DNA photoproducts: the use of different labelled antigens to control its specificity. Mutat. Res., 146: 129–133, 1985.
19. Cleaver, J. E. Methods for studying repair of DNA damaged by physical and chemical carcinogens. Methods Cancer Res., 11: 123–165, 1975.
20. Gautschi, J. R., Young, B. R., and Cleaver, J. E. Repair of damaged DNA in the absence of protein synthesis in mammalian cells. Exp. Cell Res., 76: 87–94, 1973.
21. Cleaver, J. E. DNA damage and repair in normal, xeroderma pigmentosum and XP revenant cells analyzed by gel electrophoresis: excision of cyclobutane dimers from the whole genome is not necessary for cell survival. Carcinogenesis (Lond.), 10: 1691–1696, 1989.
22. Hashem, N., Bootsma, D., Keijzer, W., Greene, A., Coriell, L., Thomas, G., and Cleaver, J. E. Clinical characteristics, DNA repair, and complementation groups in xeroderma pigmentosum patients from Egypt. Cancer Res., 40: 13–18, 1980.
23. Cleaver, J. E., Charles, W. C., and Kong, S. H. Efficiency of repair of pyrimidine dimers and psoralen monoadducts in normal and xeroderma pigmentosum human cells. Photochem. Photobiol., 40: 621–629, 1984.
24. Bootsma, D., and Hoeijmakers, J. H. The molecular basis of nucleotide excision repair syndromes. Mutat. Res., 307: 15–23, 1994.
25. Drapkin, R., Sancar, A., and Reinberg, D. Where transcription meets repair. Cell, 77: 9–12, 1994.
26. Cleaver, J. E., McDowell, M., Jones, C., Wood, R., and Karentz, D. Mutation and expression of the XPA gene in revenants and hybrids of xeroderma pigmentosum cell line. Somatic Cell Mol. Genet., 20: 327–337, 1994.
27. Ishizaki, K., Matsunaga, T., Kato, M., Nikaido, O., and Ikenaga, M. Repair of thymine dimers and (6–4) photoproducts in group A xeroderma pigmentosum cell lines harboring a transferred normal chromosome 9. Photochem. Photobiol., 56: 365–369, 1992.
28. Park, C. H., Mu, D., Reardon, J. T., and Sancar, A. The general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factor. J. Biol. Chem., 270: 4896–4902, 1995.
29. Evans, M. K., Taffe, B. G., Harris, C. C., and Bohr, V. A. DNA strand bias in the repair of the p53 gene in normal human and xeroderma pigmentosum group C fibroblasts. Cancer Res., 53: 5377–5381, 1993.
30. Cleaver, J. E. DNA repair and its coupling to DNA replication in eukaryotic cells. Biochim. Biophys. Acta, 516: 489–516, 1978.
31. Bohr, V. A. Gene specific DNA repair. Carcinogenesis (Lond.), 12: 1983–1992, 1991.
32. Terleth, C., van de Putte, P., and Brouwer, J. New insights in DNA repair: preferential repair of transcriptionally active DNA. Mutagenesis, 6: 103–111, 1991.
33. Jones, C. J., Lloyd, R. S., and Wood, R. D. Analysis of cells harboring a putative DNA repair gene reveals a lack of evidence for a second independent xeroderma pigmentosum group A correcting gene. Mutat. Res., 324: 159–164, 1994.