Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis

The Journal of Allergy and Clinical Immunology

Volumn 96, Issue 4, 1995, Pages 537-544

  Hamilos, Daniel L ^a   Leung, Donald Y M ^a   Wood, Raymond ^a   Cunninghama, Lynn ^a   Bean, Donna K ^a   Yasruelb, Z ^a   Schotmanb, E ^a   Hamid, Qutayba ^a  

^a Denver ^*  (Canada)

Author keywords

cytokine mRNA; cytokines; eosinophilia; in situ hybridization; nasal polyps; nonallergic; Sinusitis

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ALLERGY; ARTICLE; CELL INFILTRATION; CHRONIC SINUSITIS; CLINICAL ARTICLE; EOSINOPHILIA; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; NOSE POLYP; PRIORITY JOURNAL; T LYMPHOCYTE;

ADOLESCENT; ADULT; ASPIRIN; CELL MOVEMENT; COMPARATIVE STUDY; CYTOKINES; DRUG HYPERSENSITIVITY; EOSINOPHILIA; EOSINOPHILS; HUMAN; HYPERSENSITIVITY; MIDDLE AGE; NASAL POLYPS; RNA, MESSENGER; SINUSITIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES;

EID: 0028822451     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(95)70298-9     Document Type: Article

References (28)

1. A clinical and pathologic study of chronic sinusitis: the role of the eosinophil
2. Nasal polyps: local inductive microenvironment in the pathogenesis of the inflammation
3. Chronic hyperplastic sinusitis: association of tissue eosinophilia with mRNA expression of granulocyte-macrophage colony-stimulating factor and interleukin-3
4. Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia
5. Identification of activated T lymphocytes and eosinophil in bronchial biopsies in stable atopic asthma
6. Lymphocyte activation in bronchoalveolar lavage and peripheral blood in atopic asthma
7. The Microenvironmental Differentiation Hypothesis of Airway Inflammation
8. T cells and eosinophils in the pathogenesis of asthma
9. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
10. Messenger RNA expression of cytokine gene cluster, IL-3, IL-4, IL-5 and GM-CSF in allergen-induced late phase cutaneous reactions in atopic subjects
11. CD4 T-lymphocyte activation in acute severe asthma. Relationship to disease severity and atopic status
12. T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma
13. Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage
14. Human nasal polyp epithelial basophil/mast cell and eosinophil colony-stimulating activity
15. Hematopoietic growth factor production by cultured cells of human nasal polyp epithelial scrapings: kinetics, cell source, and relationship to clinical status
16. Hemopoietic function of the micro environment in chronic airway inflammation
17. Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis
18. Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics
19. Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony-stimulating factor in activated human eosinophils
20. Roles of eosinophils in allergy
21. The mast cell and its function in allergic disease
22. Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GM-CSF
23. Humoral regulation of eosinophilopoiesis in vitro: analysis of the targets of interleukin-3, granulocyte/macrophage colony-stimulating factor (GM-CSF), and interleukin-5
24. Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contribution of endothelial cell adhesion molecules
25. RANTES and macrophage inflammatory protein 1a induce the migration and activation of normal human eosinophil granulocytes
26. Formation of eosinophilic and monocytic intradermal inflammatory sites in the dog by injection of human RANTES but not human monocyte chemoattractant protein 1, human macrophage inflammatory protein 1a, or human interleukin 8
27. RANTES is a chemotactic and activating factor for human eosinophils