Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model

Journal of Clinical Investigation

Volumn 96, Issue 6, 1995, Pages 2593-2600

  Soff, Gerald A ^a   Sanderowitz, Judith ^a   Gately, Stephen ^a   Verrusio, Elaine ^a   Weiss, Ivy ^a   Brem, Steven ^a   Kwaan, Hau C ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Metastases; Plasminogen activator inhibitor type 1; Prostate carcinoma; Urokinase type plasminogen activator; galactosidase

Indexed keywords

BETA GALACTOSIDASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; TUMOR ANTIGEN; UROKINASE;

ANGIOGENESIS; ARTICLE; CELL INVASION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LUNG METASTASIS; MICROVASCULATURE; NUDE MOUSE; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROSTATE CARCINOMA; TUMOR CELL CULTURE; TUMOR GROWTH;

ANIMAL; BETA-GALACTOSIDASE; CELL LINE; CLONE CELLS; GENE EXPRESSION; HUMAN; LIVER NEOPLASMS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROSTATIC NEOPLASMS; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0028821827     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118323     Document Type: Article

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