Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

Journal of Immunology

Volumn 154, Issue 1, 1995, Pages 116-127

  Ling, P ^a   Gately, M K ^a   Gubler, U ^a   Stern, A S ^a   Lin, P ^a   Hollfelder, K ^a   Su, C ^a   Pan, Y C E ^a   Hakimi, J ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE RECEPTOR; DIMER; IMMUNOGLOBULIN G; INTERLEUKIN 12; MONOCLONAL ANTIBODY; MONOMER; PHYTOHEMAGGLUTININ; PROTEIN P40; PROTEIN SUBUNIT; RECOMBINANT INTERLEUKIN 2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING COMPETITION; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LYMPHOBLAST; LYMPHOCYTE PROLIFERATION; NONHUMAN; PEPTIDE MAPPING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMAL; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CELL LINE; CERCOPITHECUS AETHIOPS; CLONE CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; HUMAN; INTERLEUKIN-12; INTERLEUKIN-2; LIGANDS; MACROMOLECULAR SYSTEMS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN HYBRIDIZATION; RECEPTORS, INTERLEUKIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0028819316     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)