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Volumn 2, Issue 6, 1994, Pages 315-318

Pilot efficacy trial of abt‐200 in patients with major depressive disorder

Author keywords

ABT 200; clinical trial; depression

Indexed keywords

3 PHENYL 1 [(1,2,3,4 TETRAHYDRO 5,6 METHYLENEDIOXY 1 NAPHTHYL)METHYL]PYRROLIDINE; 3 PHENYL 1 [(1,2,3,4 TETRAHYDRO 5,6 METHYLENEDIOXY 1 NAPHTHYL)METHYL]PYRROLIDINE METHANESULFONATE; ANTIDEPRESSANT AGENT; PLACEBO; UNCLASSIFIED DRUG;

EID: 0028818062     PISSN: 10626417     EISSN: 15227162     Source Type: Journal    
DOI: 10.1002/depr.3050020607     Document Type: Article
Times cited : (4)

References (16)
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    • Acceleration of beta‐receptor desensitization in combined administration of antidepres‐sants and phenoxybenzamine
    • (1981) Nature , vol.290 , pp. 787-789
    • Crews, FT1    Paul, SM2    Goodwin, FK3
  • 9
    • 0028914116 scopus 로고
    • Preclinical pharmacological actions of (±)‐(1′R*, 3R*‐3‐phenyl‐l‐[1′,2′,3′,4′‐tetrahydro‐5′,6′‐methylene‐dioxy‐1′‐naphthalenyl)methyl]pyrrolidine methanesulfonate (ABT‐200), a potential antidepressant agent that antagonizes alpha‐2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine
    • (1995) J Pharmacol ExpTher , vol.272 , pp. 1160-1167
    • Hancock, AA1    Buckner, SA2    Giardina, WJ3
  • 15
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    • Rapid decrease in rat brain beta adrenergic receptor binding during combined antidepressant alpha‐2 antagonist treatment
    • (1983) J. Pharmacol Exp Ther , vol.224 , pp. 640-646
    • Scott, JA1    Crews, FT2
  • 16
    • 0028319235 scopus 로고
    • Synthesis and pharmacological characterization of ABT‐200: A putative novel anti‐depressant combining potent α‐2 antagonism with moderate NE uptake inhibition
    • (1994) Bioorg Med Chem Lett , vol.4 , pp. 1319-1322
    • Zelle, RE1    Hancock, AA2    Buckner, F3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.