Genetic and electrophysiological studies of drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission

Cell

Volumn 80, Issue 2, 1995, Pages 311-320

  Schulze, Karen L ^a,b   Broadie, Kendal ^c   Perin, Mark S ^b   Bellen, Hugo J ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SECRETORY PROTEIN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CENTRAL NERVOUS SYSTEM DISEASE; DROSOPHILA; ELECTROPHYSIOLOGY; EMBRYO; EMBRYO DEVELOPMENT; GENETIC ANALYSIS; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; SYNAPSE VESICLE;

ANIMALIA;

EID: 0028817584     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90414-X     Document Type: Article

References (40)

1. Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport
2. Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain
3. The molecular machinery for secretion is conserved from yeast to neurons
4. Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones
5. The syntaxin family of vesicular transport receptors
6. Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin
7. Development of the embryonic neuromuscular synapse of Drosophila melanogaster
8. The absence of synaptotagmin disrupts excitationsecretion coupling during synaptic transmission
9. Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking
10. A small GTP-binding protein dissociates from synaptic vesicles during exocytosis
11. A rat brain Seci homologue related to Rop and UNC18 interacts with syntaxin
12. Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission
13. Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
14. Synapsin I, a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly-purified synaptic vesicle preparation
15. Synaptic vesicles and exocytosis
16. Rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxylterminal sequence
17. Expression of Synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse
18. 2+-activated neurotransmitter release
19. Calcium dependence of neurotransmitter release and rate of spontaneous vesicle fusions are altered in Drosophila synaptotagmin mutants
20. Development of the Drosophila tracheal system
21. Accurate determination of DNA in agarose gels using the novel algorithm GelScann(10)
22. Clostridial neurotoxins: new tools for dissecting exocytosis
23. Genetic applications of an inverse polymerase chain reaction
24. The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations
25. n-Seci: a neuralspecific syntaxin-binding protein
26. The circulatory system and associated cells and tissues
27. Molecular biology and neurobiology of choline acetyltransferase
28. The Drosophila Ras 2 and Rop gene pair: a dual homology with a yeast Ras-like gene and a suppressor of its loss-of-function phenotype
29. rop, a Drosophila homolog of yeast Seci and vertebrate n-Seci/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo
30. The alimentary canal
31. SNAP receptors implicated in vesicle targeting and fusion
32. crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia
33. VAMP-1: a synaptic vesicle-associated integral membrane protein
34. Genes that control neuromuscular specificity in Drosophila
35. Cell surface antigens
36. Paralysis and early death in cysteine string protein mutants of Drosophila
37. Neuronal development in the Drosophila retina: monoclonal antibodies as molecular probes