Apolipoprotein E and alzheimer's disease: Ethnic variation in genotypic risks

Annals of Neurology

Volumn 37, Issue 2, 1995, Pages 254-259

  Maestre, Gladys ^c,d   Ottman, Ruth ^a,b,e   Stern, Yaakov ^a,c,d,e   Gurland, Barry ^c,d   Chun, Michael ^d   Tang, Ming‐Xin ^a,d   Shelanski, Michael ^c,d   Tycko, Benjamin ^c,d   Mayeux, Richard ^a,b,c,d,e  

^a Vagelos College of Physicians and Surgeons   (United States)

^b Affiliated Faculty Global Institute of Public Health   (United States)

^c Alzheimer's Disease Center   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E;

ALZHEIMER DISEASE; ARTICLE; DATA ANALYSIS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; ETHNIC DIFFERENCE; GENE AMPLIFICATION; GENOTYPE; HIGH RISK POPULATION; HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RACE DIFFERENCE; RISK ASSESSMENT; RISK FACTOR;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; CASE-CONTROL STUDIES; CAUCASOID RACE; FEMALE; GENOTYPE; HISPANIC AMERICANS; HUMAN; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGE; NEGROID RACE; ODDS RATIO; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028816355     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410370217     Document Type: Article

References (30)

1. Apolipoprotein E: high affinity binding to beta‐amyloid and increased frequency of type 4 allele in late‐onset familial Alzheimer's disease
2. Association of apolipoprotein E allele ε4 with late‐onset familial and sporadic Alzheimer's disease
3. Gene dose of apolipoprotein‐E type 4 allele and the risk of Alzheimer's disease in late onset families
4. Apolipoprotein E polymorphism and Alzheimer's disease
5. Apolipoprotein‐E genotype and Alzheimer's disease
6. Linkage of lateonset Alzheimer's disease with apolipoprotein‐E type 4 on chromosome 19
7. Apolipoprotein‐E ε4 allele distributions in late‐onset Alzheimer's disease and in other amyloid‐forming diseases
8. The apolipoprotein ε4 allele in patients with Alzheimer's disease
9. Apolipoprotein E type 2 allele decreases the risk for late onset Alzheimer's disease
10. Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage
11. Apolipoprotein E polymorphism and atherosclerosis
12. The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations
13. Ferrell RE. Genetic studies of human apolipoproteins. VI. Common polymorphism of apolipoprotein E in blacks
14. HLA‐A/B haplotype frequencies among U. S. Hispanic and African‐American populations
15. Diagnosis of dementia in a heterogenous population: a comparison of paradigm‐based diagnosis and physician's diagnosis
16. Diagnosis of dementia in a heterogenous population: development of a neuropsychological paradigm and quantified correction for education
17. Clinical diagnosis of Alzheimer's disease: report of NINCDS‐ADRDA Work Group under the auspices of the Department of Health and Human Services Task Force on Alzheimer's Disease
18. Genetic susceptibility and head injury as risk factors for Alzheimer's disease among community‐dwelling elderly persons and their first‐degree relatives
19. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhAI
20. Frequencies and causes of cognitive impairment and dementia in a community‐based registry
21. Relation of apolipoprotein E phenotype to myocardial infarction and mortality from coronary artery disease
22. Genetic studies of human apolipoproteins. X. The effect of the apolipoprotein E polymorphism on quantitative levels of lipoproteins in Nigerian balcks
23. The gender‐specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regression relationships with concomitants
24. Binding of human apolipoprotein E to β‐A4 peptide: isoform‐specific effects and implications for late‐onset Alzheimer's disease
25. Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype