Characterization of the Functional Specificity of a Cloned T-Cell Receptor Heterodimer Recognizing the MART-1 Melanoma Antigen

Cancer Research

Volumn 55, Issue 4, 1995, Pages 748-752

  Cole, David J ^a   Weil, Daniel P ^a   Shilyansky, Joel ^a   Custer, Mary ^a   Kawakami, Yutaka ^a   Rosenberg, Steven A ^a   Nishimura, Michael I ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; DIMER; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA A2 ANTIGEN; INTERLEUKIN 2; MONOCLONAL ANTIBODY; SYNTHETIC PEPTIDE; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR ANTIGEN;

ADOPTIVE TRANSFER; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LEUKEMIA CELL LINE; LYMPHOCYTE CLONE; MELANOMA; MELANOMA CELL; MOLECULAR CLONING; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; EPITOPES; HUMAN; MELANOMA; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0028815876     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Rosenberg S. A., Speiss, P., and Lafreniere, R. A. A new approach to the adoptive immunotherapy of cancer with tumor infiltrating lymphocytes. Science (Washington DC), 233:1318–1321, 1986.
2. Rosenberg, S. A. The immunotherapy and gene therapy of cancer. J. Clin. Oncol., 10:180–199, 1992.
3. Rosenberg, S. A., Packard, B. S., Aebersold, P. M., et al. Use of tumor infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. N. Engl. J. Med., 319:1676–1680, 1988.
4. Darrow, T. L., Slinghoff, C. L., Jr., and Siegler, H. F. The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes:evidence for shared tumor-antigens. J. Immunol., 142:3329–3335, 1989.
5. Kawakami, Y., Zakut, R., Topalian, S. L., Stotter, H., and Rosenberg, S. A. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. J. Immunol., 148:638–643, 1992.
6. Topalian, S. L., Solomon, D., and Rosenberg, S. A. Tumor specific cytolysis by lymphocytes infiltrating human melanomas. J Immunol., 142:3714–3724, 1989.
7. Matis, L. A. The molecular basis of T cell specificity. Annu. Rev. Immunol., 8:65–82, 1990.
8. Bjorkman, P. J., Saper, M. A., Samraoui, B., Bennet, W. S., Strominger, J. L., and Wiley, D. C. The foreign antigen binding site and T cell recognition regions of class I histocompatability antigens. Nature (Lond.), 329:512–518, 1987.
9. Van der Bruggen, P., Travereari, P. C., Chomez, P., Lurquin, C., DePlaen, E., Van den Eynde, B., Knuth, A., and Boon, T. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science (Washington DC), 254:1643–1647, 1991.
10. Brichard, V., Van Pel, W., Wolfel, T., DePlaen, E., Lethe, B., Coulie, P., and Boon, T. 1993. The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 775:489–495, 1993.
11. Gaugler B., Van den Eynde, B., Van der Bruggen, P., Romero, P., Gaforio, J. J., De Plaen, E., Lethe, B., Brasseur, F., and Boon, T. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med., 179:921–930, 1994.
12. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. R., Rivoltini, L., Topalian, S. L., Miki, T., and Rosenberg, S. A. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. USA, 91:3515–3519, 1994.
13. Kawakami, Y., Eliyahu, S., Delgado, C. H., Robbins, P. F., Sakaguchi, K., Appella, E., Yannelli, J. R., Adema, G. J., Miki, T., and Rosenberg, S. A. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc. Natl. Acad. Sci. USA, 91:6458–6462, 1994.
14. Cox, A. L., Skipper, J., Chen, Y., and Henderson, R. A. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. Science (Washington DC), 264:716–719, 1994.
15. Kawakami, Y., Eliyahu, S., Sakaguchi, K., Robbins, P. F., Rivoltini, L., Yannelli, J. R., Appella, E., and Rosenberg, S. A. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2 restricted tumor infiltrating lymphocytes. J. Exp. Med., 180:347–352, 1994.
16. Traversari, C., Van der Bruggen, P., Luescher, I. F., Lurquin, C., Chomez, P., Van Pel, A., De Plaen, E., Amar-Costesec, A., and Boon, T. A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 cytolytic lymphocytes directed against tumor antigen MZ2-E. J. Exp. Med., 176:1453–1456, 1994.
17. Cole, D. J., Weil, D. P., Shamamian, P., Rivoltini, L., Kawakami, Y., Topalian, S., Jennings, C., Eliyahu, S., Rosenberg, S. A., and Nishimura, M. I. Identification of MART-1 specific T-cell receptors:T-cells utilizing distinct T-cell receptor variable and joining regions recognize the same tumor epitope. Cancer Res., 54:5265–5268, 1994.
18. Shilyansky, J., Nishimura, M. I., Yannelli, J. R., Kawakami, Y., Jacknin, L. S., Charmley, P., and Rosenberg, S. A. T-cell receptor usage by melanoma-specific clonal and highly oligoclonal tumor-infiltrating lymphocyte lines. Proc. Natl. Acad. Sci. USA, 91:2829–2833, 1994.
19. Hall, B. L., and Finn, O. J. PCR-based analysis of the T-cell receptor V0 multigene family:experimental parameters affecting its validity. Biotechniques, 13:248–257, 1992.
20. Engel, I., Ottenhoff, T. H. M., and Klausner, R. D. High-efficiency expression and solubilization of functional T cell antigen receptor heterodimers. Science (Washington DC), 256:1318–1321, 1992.
21. Sanger, F., Nicklen, S., Coulson, A. R. DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74:5463–5467, 1977.
22. Weiss, A., and Stobo, J. D. Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T-cell line. J. Exp. Med., 160:1284–1288, 1984.
23. - T cell receptor/CD3 complex:clues from a T cell variant with a mutated T cell receptor-a chain. J. Immunol., 145:1761–1767, 1990.
24. Nishimura, M. I., Kawakami, Y., Charmley, P., O'Neil, B., Shilyansky, J., Yannelli, J. R., Rosenberg, S. A., and Hood, L. T-cell receptor repertoire in tumor-infiltrating lymphocytes:analysis of melanoma-specific long-term lines. J. Immunother., 16:85–94, 1994.
25. Sensi, M., Salvi, S., Castelli, C., Maccalli, C., Mazzocchi, A., Mortarini, R., Nicolini, G., Herlyn, M., Parmiani, G., and Anichini, A. T cell receptor (TCR) structure of autologous melanoma-reactive cytotoxic T lymphocyte (CTL) clones:tumor-infiltrating lymphocytes overexpress in vivo the TCR β chain sequence used by an HLA-A2-restricted and melanocyte-lineage-specific CTL clone. J. Exp. Med., 178:1231–1248, 1993.
26. Hwu, P., Shafer, G. E., Treisman, J., Schindler, D. G., Gross, G., Cowerd, R., Rosenberg, S. A., and Eshhar, Z. Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor γ chain. J. Exp. Med., 178:361–366, 1993.