Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance

Journal of Clinical Investigation

Volumn 96, Issue 5, 1995, Pages 2339-2347

  Berg, Daniel J ^a   Kühn, Ralf ^b   Rajewsky, Klaus ^b   Müller, Werner ^b   Menon, Satish ^a   Davidson, Natalie ^a   Grünig, Gabriele ^a   Rennick, Donna ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

endotoxic shock; endotoxin tolerance; IL 10; Shwartzman reaction

Indexed keywords

CYTOKINE; ESCHERICHIA COLI ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; INTERFERON ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; NITRATE; NITRIC OXIDE; RECOMBINANT INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; IMMUNOLOGICAL TOLERANCE; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; SEPTIC SHOCK; SHWARTZMAN PHENOMENON;

EID: 0028815553     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118290     Document Type: Article

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