The Neuropathology and Epidemiology of Bovine Spongiform Encephalopathy

Brain Pathology

Volumn 5, Issue 1, 1995, Pages 91-103

  Wells, Gerald A H ^a   Wilesmith, John W ^a  

^a VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; BRAIN SPONGIOSIS; CATTLE; CONFERENCE PAPER; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRION DISEASE; ULTRASTRUCTURE; UNITED KINGDOM;

ANIMAL; BRAIN; BRAIN CHEMISTRY; CATTLE; DISEASE OUTBREAKS; DISEASE TRANSMISSION, VERTICAL; ENCEPHALOPATHY, BOVINE SPONGIFORM; GREAT BRITAIN; IMMUNOHISTOCHEMISTRY; PRIONS;

EID: 0028809091     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1995.tb00580.x     Document Type: Article

References (73)

1. A novel progressive spongiform encephalopathy in cattle
2. Unconventional slow viruses
3. Sub‐acute, transmissible spongiform encephalopathies: current concepts and future needs
4. Bovine spongiform encephalopathy: a neuropathological perspective
5. Bovine spongiform encephalopathy
6. Recently described scrapie‐like encephalopathies of animals: case definitions
7. The discovery of bovine spongiform encephalopathy and observations on the vacuolar changes
8. Bovine spongiform encephalopathy: epidemiological studies
9. Comparative pathology of the new spongiform encephalopathies
10. The pathology of natural and experimental scrapie
11. Natural infection of sheep with scrapie virus
12. Virologic and neurohistologic findings in dairy goats affected with natural scrapie
13. Natural infection of Suffolk sheep with scrapie virus
14. A morphometric and immunohistochemical study of the vestibular nuclear complex in bovine spongiform encephalopathy
15. Numbers of neurons in vacuolated and non‐vacuolated neuroanatomical nuclei in bovine spongiform encephalopathy‐affected brains
16. Cerebrovascular amyloidosis in scrapie‐affected sheep
17. Cerebral amyloidosis in natural scrapie of Icelandic sheep is of rare occurrence
18. The sequential development of the brain lesions of scrapie in three strains of mice
19. Scrapie in mice. Agent‐strain differences in the distribution and intensity of grey matter vacuolation
20. Scrapie prion protein accumulation correlates with neuropathology and incubation times in hamsters and transgenie mice
21. Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
22. Transmission of bovine spongiform encephalopathy to mice
23. Transmission of bovine spongiform encephalopathy and scrapie to mice
24. Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier
25. Transmission to mice, sheep and goats and bioassay of bovine tissues
26. Unsuspected early neuronal loss in scrapie‐infected mice revealed by morphometric analysis
27. Comparative ultrastructural neuropathology of naturally occurring bovine spongiform encephalopathy and experimentally induced scrapie and Creutzfeldt‐Jakob disease
28. Ultrastructural pathology of axons and myelin in experimental scrapie in hamsters and bovine spongiform encephalopathy in cattle and a comparison with the panencephalopathic type of Creutzfeldt‐Jakob disease
29. Tubulovesicular structures
30. Fibrils from brains of cows with new cattle disease contain scrapie‐associated protein
31. Post mortem immunodiagnosis of scrapie and bovine spongiform encephalopathy
32. Assessment of western immunoblotting for the confirmatory diagnosis of ovine scrapie and bovine spongiform encephalopathy (BSE)
33. Immunologic and molecular biologic studies of prion proteins in bovine spongiform encephalopathy
34. Immunodetection of a disease specific PrP fraction in scrapie‐affected sheep and BSE‐affected cattle
35. Bovine spongiform encephalopathy: detection and quantitation of fibrils, fibril protein (PrP) and vacuolation in brain
36. Bovine spongiform encephalopathy: detection of fibrils in the central nervous system is not affected by autolysis
37. Hydrated autoclave pretreatment enhancement of prion protein immunoreactivity in formalin‐fixed bovine spongiform encephalopathy‐affected brain
38. Observations on light microscopic immunohistochemical labelling with polyclonal antisera to PrP in transmissible spongiform encephalopathies of animals
39. Configurations and topographic distribution of PrP in the central nervous system in bovine spongiform encephalopathy: an immunohistochemical study
40. Changes in the localization of brain prion proteins during scrapie infection
41. Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie
42. Bovine spongiform encephalopathy: diagnostic significance of vacuolar changes in the selected nuclei of the medulla oblongata
43. Correlation between the results of a histopathological examination and the detection of abnormal brain fibrils in the diagnosis of bovine spongiform encephalopathy
44. Bovine spongiform encephalopathy (BSE): epidemiology, low dose exposure and risks
45. Epidemiology of bovine spongiform encephalopathy
46. Bovine spongiform encephalopathy: a brief epidemiography, 1985–1991
47. Epidemiology of bovine spongiform encephalopathy and related diseases
48. BSE: epidemiological approaches, trials and tribulations
49. Bovine spongiform encephalopathy and related diseases: an epidemiological overview
50. An epidemiologist's view of bovine spongiform encephalopathy
51. Update on the epidemiology of bovine spongiform encephalopathy in Great Britain
52. Bovine spongiform encephalopathy: epidemiological factors associated with the emergence of an important new animal pathogen in Great Britain
53. Bovine spongiform encephalopathy: descriptive epidemiological features 1985 ‐ 1990
54. Bovine spongiform encephalopathy: case‐control studies of calf feeding practices and meat and bone meat inclusion in proprietary concentrates
55. The distribution pattern of neuronal vacuolation in bovine spongiform encephalopathy (BSE) is constant
56. Frequencies of PrP gene variants in healthy cattle and cattle with BSE in Scotland
57. The inheritance of susceptibility to BSE
58. An assessment of the genetics of scrapie in sheep and mice
59. Bovine spongiform encephalopathy: aspects of the clinical picture and analyses of possible changes 1986–1990
60. Bovine spongiform encephalopathy: recent observations on the age‐specific incidences
61. Bovine spongiform encephalopathy: observations on the incidence in 1992
62. Bovine spongiform encephalopathy: epidemiological studies on the origin
63. Comparison of bovine spongiform encephalopathy risk factors in the United States and Great Britain
64. BSE risk assessment and surveillance in Spain