Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia

Annals of Neurology

Volumn 38, Issue 5, 1995, Pages 755-762

  Glass, Jonathan D ^a   Fedor, Helen ^a   Wesselingh, Steven L ^b   McArthur, Justin C ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COAT PROTEIN; GLYCOPROTEIN GP 41; MONOCLONAL ANTIBODY HAM 56; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BASAL GANGLION; CLINICAL ARTICLE; CONTROLLED STUDY; DEMENTIA; DISEASE SEVERITY; FEMALE; FRONTAL LOBE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MALE; MICROGLIA; PATHOGENESIS; PRIORITY JOURNAL;

ADULT; AIDS DEMENTIA COMPLEX; ANALYSIS OF VARIANCE; ANTIBODIES; BASAL GANGLIA; BRAIN; FEMALE; FRONTAL LOBE; HIV ENVELOPE PROTEIN GP41; HIV-1; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MICROGLIA; MIDDLE AGE; PROSPECTIVE STUDIES; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SURVIVAL ANALYSIS; TUMOR NECROSIS FACTOR; ZIDOVUDINE;

EID: 0028808135     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410380510     Document Type: Article

References (40)

1. The AIDS dementia complex: I. Clinical features
2. Neuronal loss in the frontal cortex in HIV infection
3. Reduced basal ganglia volume in HIV‐1‐associated dementia: results from quantitative neuroimaging
4. Patterns of cerebral atrophy in HIV‐1 infected individuals: results of a quantitative MRI analysis
5. Cortical dendritic pathology in human immunodeficiency virus encephalitis
6. Neocortical damage during HIV infection
7. Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms
8. Understanding the AIDS dementia complex
9. HIV‐associated disease of the nervous system: review of nomenclature and proposal for neuropathology‐based terminology
10. Neuropathology of human immunodeficiency virus infection
11. The AIDS dementia complex. II. Neuropathology
12. PCR identification of HIV‐1 DNA sequences in brain tissue of patients with AIDS encephalopathy
13. The involvement of the cerebral cortex in human immunodeficiency virus encephalopathy: a morphological and immunohistochemical study
14. Detection of HIV proviral DNA in cortex and white matter of AIDS brains by non‐isotopic polymerase chain reaction: correlation with diffuse poliodystrophy
15. Low levels of human immunodeficiency virus replication in the brain tissue of children with severe acquired immunodeficiency syndrome encephalopathy
16. High levels of unintegrated HIV‐1 DNA in brain tissue of AIDS dementia patients
17. In situ detection of polymerase chain reaction‐amplified HIV‐1 nucleic acids and tumor necrosis factor‐alpha RNA in the central nervous system
18. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
19. Clinicalneuropathological correlation in HIV‐associated dementia
20. M‐CSF production by HIV‐1‐infected monocytes and its intrathecal synthesis: implications for neurological HIV‐1‐related disease
21. Cerebrospinal fluid human immunodeficiency virus type 1 (HIV‐1) p24 antigen levels in HIV‐1‐related dementia
22. Quantifying HIV‐1 proviral DNA via the polymerase chain reaction (PCR) in cerebrospinal fluid (CSF) and blood of seropositive individuals with and without neurologic abnormalities
23. The role of mononuclear phagocytes in HTLV‐III/LAV infection
24. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy
25. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients
26. Macrophages and microglia in HIV‐related CNS neuropathology
27. Human immunodeficiency virus‐1 infection of the nervous system: an autopsy study of 268 adult, pediatric, and fetal brains
28. Morphology and distribution of HIV‐1 gp41‐positive microglia in subacute AIDS encephalitis
29. Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus‐type (HIV‐1) infections: report of a Working Group of the American Academy of Neurology AIDS Task Force
30. The AIDS dementia complex
31. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS)
32. Macrophage markers in diagnostic neuropathology
33. HIV antigen and DNA in AIDS spinal cords correlate with macrophage infiltration but not with vacuolar myelopathy
34. Cytokine expression in the brain during AIDS
35. Zidovudine therapy and HIV encephalitis: a 10‐year neuropathological survey
36. Neuropathological evidence that zidovudine reduces incidence of HIV infection of brain
37. Rapid turnover of plasma virions and CD4 lymphocytes in HIV‐1 infection
38. HIV coat protein gp120 induces soluble neurotoxins in culture medium
39. Demented and nondemented patients with AIDS differ in brain‐derived human immunodeficiency virus type 1 envelope sequences