Does antisense exist?

Nature Medicine

Volumn 1, Issue 11, 1995, Pages 1119-1121

  Stein, C A ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE;

GENE EXPRESSION; NOTE; PRIORITY JOURNAL;

BASE SEQUENCE; OLIGONUCLEOTIDES, ANTISENSE; POLYMERS; PROTEIN BINDING; RESEARCH DESIGN; THIONUCLEOTIDES;

EID: 0028806487     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1195-1119     Document Type: Article

References (12)

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2. Yakubov, L. et al. Oligodeoxynucleotides interact with recombinant CD4 at multiple sites. J. Biol. Chem. 268, 18818-18823 (1993).
3. Stein, C.A., Cleary, A.M., Yakubov, L. & Lederman, S. Phosphorothioate oligodeoxynucleotides bind to the third variable loop domain (v3) of human immunodeficiency virus Type 1 gpl20. Antisense Res. Devel. 3, 19-31 (1993).
4. Guvakova, M.A., Yakubov, L.A., Vlodavsky, I., Tonkinson, J.L. & Stein, C.A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J. biol. Chem. 270, 2620-2627 (1995).
5. Simons, M., Edelman, E., DeKeyser, J., Langer, R. & Rosenberg, R. Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature 359, 67-70 (1992).
6. Burgess, T. et al. The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is casued by a nonantisense mechanism. Proc. natn. Acad. Sci. U.S.A. 92, 4051-4055 (1995).
7. Lallier, T., and Bronner-Fraser, M. Inhibition of neural crest cell attachment by integrin antisense oligonucleotides. Science 259, 692-695 (1993).
8. Maltese, J., Sharma, H., Vassilev, L. & Narayanan, R. Sequence context of antisense RelA/NF-KB phosphorothioates determines specificity. Nucleic Acids Res. 23, 1146-1151 (1995).
9. Krieg, A. et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374, 546-549 (1995)
10. Tamamoto, T., Yamamoto, S., Kataoka, T. & Tokunaga, T. Ability of oligonucleotides with certain palindromes to induce interferon production and augment natural killer cell activity is associated with their base length. Antisense Res. Devel. 4, 119-122 (1994).
11. Yamamoto, S. et al. DNA from bacateria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth. Microbiol. Immun. 36, 983-987 (1992).
12. Stein, C.A. & Krieg, A. Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides. Antisense Res. Devel. 4, 67-69 (1994).