Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms: Role for p53-independent induction of gadd45 in initiating death

Journal of Clinical Investigation

Volumn 96, Issue 4, 1995, Pages 1874-1886

  De Vente, James E ^a   Kukoly, Cynthia A ^a   Bryant, Winifred O ^a   Posekany, Karla J ^a   Chen, Jianming ^a   Fletcher, Donald J ^a   Parker, Peter J ^b   Pettit, George J ^c   Lozano, Guillermina ^d   Cook, Paul P ^a   Ways, D Kirk ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c ARIZONA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Apoptosis; Breast cancer; p53; Phorbol esters; Protein kinase C

Indexed keywords

BRYOSTATIN 1; ENZYME ACTIVATOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CYCLINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENES, P53; HUMAN; ISOENZYMES; LACTONES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEINS; RETINOBLASTOMA PROTEIN; SUPPORT, U.S. GOV'T, P.H.S.; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0028805717     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118233     Document Type: Article

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