The neurobiology and genetics of Alzheimer's disease

Human Psychopharmacology: Clinical and Experimental

Volumn 10, Issue 4 S, 1995, Pages S243-S246

  Lovestone, Simon ^a  

^a SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; CHROMOSOME 21; CONFERENCE PAPER; GENETIC POLYMORPHISM; HUMAN; MUTATION; NEUROBIOLOGY; PRIORITY JOURNAL;

EID: 0028802993     PISSN: 08856222     EISSN: 10991077     Source Type: Journal    
DOI: 10.1002/hup.470101008     Document Type: Article

References (36)

1. A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities
2. Earlyonset Alzheimer's disease caused by mutations at codon 717 of the beta‐amyloid precursor protein gene
3. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
4. Subtypes and differential laminar distributions of beta A4 deposits in Alzheimer's disease: relationship with the intellectual status of 26 cases
5. Cleavage of amyloid beta peptide during constitutive processing of its precursor
6. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein
7. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
8. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
9. Targeting of cell‐surface betaamyloid precursor protein to lysosomes: alternative processing into amyloid‐bearing fragments
10. Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated
11. Mutation in codon 713 of the beta‐amyloid precursor protein gene presenting with schizophrenia
12. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell‐surface receptor
13. Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
14. A68: a major subunit of paired helical filaments and derivatized forms of normal Tau
15. Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type
16. Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus
17. A Familial Alzheimer's Disease Locus on Chromosome 1
18. Cytoskeletal abnormalities in Alzheimer's disease
19. Genetic tests and Alzheimer's disease?
20. Alzheimer's debate boils over
21. Amyloid core plaque protein in Alzheimer's disease and Down syndrome
22. 2+ homeostasis in Alzheimer's disease
23. Neuritic pathology and dementia in Alzheimer's disease
24. Alzheimer's Disease: Recent Advances in Molecular Pathology and Genetics
25. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N‐terminus of beta‐amyloid
26. A locus for early onset familial Alzheimer's disease on the long arm of chromosome 14 proximal to the alpha 1 antichymotrypsin gene
27. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease
28. Linkage studies in familial Alzheimer's disease: evidence for chromosome 19 linkage
29. ε4 with late‐onset familial and sporadic Alzheimer's disease
30. Genetic association and linkage analysis of the apolipoprotein Cll locus and familial Alzheimer's disease
31. Secretion of β‐amyloid precursor protein cleaved at the amino terminus of the β‐amyloid peptide
32. Cloning of a gene bearing missense mutations in early‐onset familial Alzheimer's disease
33. Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform‐specific effects and implications for late‐onset Alzheimer disease
34. Observation on the brains of demented old people
35. Alzheimer's disease: The apolipoprotein E connection
36. Amyloid precursor protein gene mutation in early‐onset Alzheimer's disease