Cloning and Expression of CD24 Gene in Human Hepatocellular Carcinoma: A Potential Early Tumor Marker Gene Correlates with p53 Mutation and Tumor Differentiation

Cancer Research

Volumn 55, Issue 20, 1995, Pages 4717-4721

  Huang, Lan Ru ^a   Hsu, Hey Chi ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TUMOR MARKER;

ADOLESCENT; ADULT; AGED; ARTICLE; DNA LIBRARY; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; MARKER GENE; MOLECULAR CLONING; PRIORITY JOURNAL; PROGNOSIS; TUMOR DIFFERENTIATION;

ALPHA-FETOPROTEINS; AMINO ACID SEQUENCE; ANTIGENS, CD; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; COMPARATIVE STUDY; DNA PRIMERS; DNA, COMPLEMENTARY; DNA, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; GENES, STRUCTURAL, NEOPLASM; HUMAN; LIVER; LIVER NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTATION; PROGNOSIS; RNA, MESSENGER; RNA, NEOPLASM; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; TUMOR MARKERS, BIOLOGICAL;

EID: 0028802607     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Editorial. Hepatocellular cancer: Differences between high and low incidence regions [Review]. Lancet, 2: 1183–1184, 1987.
2. Beasley, R. P. Hepatitis B virus: the major etiology of hepatocellular carcinoma. Cancer (Phila.), 61: 1942–1956, 1988.
3. Sager, R. Tumor suppressor genes: the puzzle and the promise. Science (Washington DC), 246: 1406–1412, 1989.
4. Aaronson, S. A. Growth factors and cancer. Science (Washington DC), 254: 1146–1153, 1991.
5. Liang, P., and Pardee, A. B. Differential display of eukaryotic mRNA by means of the polymerase chain reaction. Science (Washington DC), 257: 967–971, 1992.
6. Nishio, Y., Aiella, L. P., and King, G. L. Glucose induced genes in bovine aortic smooth muscle cells identified by mRNA differential display. FASEB J., 8: 103–106, 1994.
7. Alterman, L. A., Crispe, I. N., and Kinnon, C. Characterization of the murine heat-stable antigen: an hematolymphoid differentiation antigen defined the by J lid, Ml/69 and B2A2 antibodies. Eur. J. Immunol., 20: 1597–1602, 1990.
8. Mittler, R. S., Talle, M. A., Carpenter, K., Rao, P. E., and Goldstein, G. Generation and characterization of monoclonal antibodies reactive with human B lymphocytes. J. Immunol., 131: 1754–1761, 1983.
9. Linton, P. J., Decker, D. J., and Klinman, N. R. Primary antibody-forming cells and secondary B cells are generated from separate precursor cell subpopulations. Cell, 59: 1049–1059, 1989.
10. Fischer, G. F., Majdic, O., Gadd, S., and Knapp, W. Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules. J. Immunol., 144: 638–641, 1990.
11. Yin, X.-M., Lee, W. T., and Vitetta, E. S. Changes in expression of Jlld on murine B cells during activation and generation of memory. Cell. Immunol., 137: 448–460, 1991.
12. Kay, R., Rosten, P. M., and Humphries, R. K. CD24, a signal transducer modulating B cell activation response, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor. J. Immunol., 147: 1412–1416, 1991.
13. Hitsumoto, Y., Nakano, A., Ohnishi, H., Hamada, F., Saheki, S., and Takeuchi, N. Purification of the murine heat-stable antigen from erythrocytes. Biochem. Biophys. Res. Commun., 187: 773–777, 1992.
14. Nedelec, J., Pierres, M., Moreau, H., Barbet, J., Naquet, P., Faivre-Sarrailh, F., and Rougon, G. Isolation and characterization of a novel glycosyl-phosphatidylinositol-anchored glycoconjugate expressed by developing neurons. Eur. J. Biochem., 203: 433–442, 1992.
15. Pierres, M., Naquet, P., Barbet, J., Marchetto, S., Maries, I., Devaux, C., Barad, M., Hyman, R., and Rougon, G. Evidence that murine hematopoietic cell subset marker Jlld is attached to a glycosyl-phosphatidylinositol membrane anchor. Eur. J. Immunol., 17: 1781–1785, 1987.
16. Stefanova, I., Horejsi, V., Ansotegui, I. J., Knapp, W., and Stockinger, H. GPI-anchored cell-surface molecules complexed to protein tyrosine kinases. Science (Washington DC), 254: 1016–1019, 1991.
17. Droz, D., Rousseau-Merck, M.-F., Jaubert, F., Diebold, N., Nezelof, C., Adafer, E., and Mouly, H. Cell differentiation in Wilms'tumor (nephroblastoma): an immuno-histochemical study. Hum. Pathol., 21: 536–544, 1990.
18. Shirasawa, T., Akashi, T., Sakamoto, K., Takahashi, H., Maruyama, N., and Hirokawa, K. Gene expression of CD24 core peptide molecule in developing brain and developing non-neural tissues. Dev. Dyn., 198: 1–13, 1993.
19. Figarella-Branger, H., Moreau, H., Pellissier, J. F., Bianco, N., and Rougon, G. CD24, a signal-transducing molecule expressed on human B lymphocytes, is a marker for human regenerating muscle. Acta. Neuropathol., 86: 275–284, 1993.
20. Kadmon, G., Eckert, M., Sammar, M., Schachner, M., and Altevogt, P. Nectadrin, the heat stable antigen, is a cell adhesion molecule. J. Cell Biol., 118: 1245–1258, 1992.
21. Jackson, D., Waibel, R., Weber, E., Bell, J., and Stahel, R. A. CD24, a signal-transducing molecule expressed on human B cells, is a major surface antigen on small cell lung carcinomas. Cancer Res., 52: 5264–5270, 1992.
22. Karran, L., Jones, M., Morley, G., Noorden, S. V., Smith, P., Lampert, I., and Griffin, B. E. Expression of a B-cell marker, CD24, on nasopharyngeal carcinoma cells. Int. J. Cancer, 60: 562–566, 1995.
23. Hsu, H. C., Peng, S. Y., Lai, P. L., Chu, J. S., and Lee, P. H. Mutations of p53 gene in hepatocellular carcinoma (HCC) correlate with tumor progression and patient prognosis: a study of 138 patients with unifocal HCC. Int. J. Oncol., 4: 1341–1347, 1994.
24. Edmondson, H. A. Tumor of the liver and intrahepatic bile ducts, section VII, fascicle 25. Washington, DC: Armed Forces Institute of Pathology, 1985.
25. Hsu, H. C., Su, I. J., Lai, M. Y., Chen, D. S., Chang, M. H., Chuang, S. M., and Sung, J. L. Biologic and prognostic significance of hepatocyte hepatitis B core antigen expressions in the natural course of chronic hepatitis B virus infection. J. Hepatol., 50: 45–50, 1987.
26. Hsu, H. C., Tseng, H. J., Lai, P. L., Lee, P. H., and Peng, S. Y. Expression of p53 gene in 184 unifocal hepatocellular carcinomas: association with tumor growth and invasiveness. Cancer Res., 53: 4691–4694, 1993.
27. Hsu, H. C., Sheu, J. C., Lin, Y. H., Chen, D. S., Lee, C. S., Hwang, L. Y., and Beasley, R. P. Prognostic histologic parameters in resected small hepatocellular carcinoma: a comparison with resected large hepatocellular carcinoma (HCC). Cancer (Phila.), 56: 672–680, 1985.
28. Hsu, H. C., Wu, T. T., Wu, M. Z., Sheu, J. C., Lee, C. S., and Chen, D. S. Tumor invasiveness and prognosis in resected hepatocellular carcinoma: clinical and pathogenetic implications. Cancer (Phila.), 61: 2095–2099, 1988.
29. Chirgwin, J. M., Przybyla, A. E., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry, 18: 5294–5299, 1979.
30. Liang, P., Averboukh, L., Keyomarsi, K., Sager, R., and Pardee, A. B. Differential display and cloning of mRNA from human breast cancer versus mammary epithelial cells. Cancer Res., 52: 6966–6968, 1992.
31. Peng, S. Y., Lai, P. L., Chu, J. S., Lee, P. H., Tsung, P. T., Chen, D. S., and Hsu, H. C. Expression and hypomethylation of a-fetoprotein gene in unicentric and multicentric human hepatocellular carcinoma. Hepatology, 17: 35–41, 1993.
32. Hsu, H. C., Chiou, T. J., Chen, Z. Y., Lee, C. S., Lee, P. H., and Peng, S. Y. Clonality and clonal evolution of hepatocellular carcinoma with multiple nodules. Hepatology, 13: 923–928, 1991.
33. Hough, M. R., Rosten, P. M., Sexton, T. L., Kay, R., and Humphries, R. K. Mapping of CD24 and homologous sequences to multiple chromosomal loci. Genomics, 22: 154–161, 1994.
34. Miller, B. A., Antognetti, G., and Springer, T. A. Identification of cell surface antigens present on murine hematopoietic stem cells. J. Immunol., 134: 3286–3290, 1985.
35. Wenger, R. H., Ayane, M., Bose, R., Kohler, G., and Nielsen, P. J. The genes for a hematopoietic differentiation marker called the heat-stable antigen. Eur. J. Immunol., 21: 1039–1046, 1991.
36. Ennas, M. G., Silvetti, C. E., Sogos, V., Riva, A., Torelli, S., and Gremo, F. Immunocompetent cell markers in human fetal astrocytes and neurons in culture. J. Neurosci. Res., 32: 424–436, 1992.
37. Rougon, G., Alterman, L. A., Dennis, K., Guo, X. J., and Kinnon, C. The murine heat-stable antigen: a differentiation antigen expressed in both the hematolymphoid and neural cell lineages. Eur. J. Immunol., 21: 1397–1402, 1991.
38. Droz, D., Zachar, D., Charbit, L., Gogusev, J., Chretien, Y., and Iris, L. Expression of the human nephron differentiation molecules in renal cell carcinomas. Am. J. Pathol., 137: 895–904, 1990.