Intracoronary low-dose β-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model

Circulation

Volumn 92, Issue 10, 1995, Pages 3025-3031

  Waksman, Ron ^a   Robinson, Keith A ^a   Crocker, Ian R ^a   Wang, Chris ^b   Gravanis, Michael B ^a   Cipolla, Gustavo D ^a   Hillstead, Richard A ^c   King III, Spencer B ^a,d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c Novoste Corporation   (United States)

^d EMORY UNIVERSITY HOSPITAL   (United States)

Author keywords

angioplasty; coronary arteries; irradiation; radiation; restenosis

Indexed keywords

IRIDIUM 192; STRONTIUM 90; YTTRIUM 90;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BALLOON CATHETER; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; ELECTRON THERAPY; FEMALE; GUINEA PIG; INTRACORONARY INFUSION; LOW ENERGY RADIATION; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 0028799838     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.92.10.3025     Document Type: Article

References (26)

1. Holmes DR Jr, Vlietstra RE, Smith HC, Vetrovec GW, Kent KM, Cowely MJ, Faxon DP, Gruentzig AR, Kelsey SF, Detre KM, van Raden MJ, Mock MB. Restenosis after percutaneous transluminal coronary angioplasty (PTCA): a report from the PTCA registry of the National Heart, Lung and Blood Institute. Am J Cardiol. 1984; 53:77C-81C.
2. Forrester JS, Fishbein M, Helfant R, Fagin J. A paradigm for restenosis based on cell biology: clues for the development of new preventive therapies. J Am Coll Cardiol. 1991;17:758-769.
3. Liu MW, Roubin GS, King SB III. Restenosis after coronary angioplasty: potential biologic determinants and role of intimal hyperplasia. Circulation. 1989;79:1374-1387.
4. Austin GE, Ratliff MB, Hollman J. Intimal proliferation of smooth muscle cells as an explanation for recurrent coronary artery stenosis after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1985;6:369-375.
5. Puck TT, Morkovin D, Marcus PI. Action of x-rays on mammalian cells, II: survival curves of cells from normal human tissues. J Exp Med. 1957;106:485-500.
6. Sinclair WK. Cyclic x-ray response in mammalian cells in vitro. Radiat Res. 1968;63:620-643.
7. Fischer-Dzoga K, Dimitrievich GS, Griem ML. Differential radio-sensitivity of aortic cells in vitro. Radiat Res. 1984;99:536-546.
8. Hall EJ. Cell-survival curves. In: Radiobiology for the Radiologist. ed 3. Philadelphia, Pa: Lippincott: 1994.
9. Shimotakahara S, Mayberg MR. Gamma irradiation inhibits neointimal hyperplasia in rats after arterial injury. Stroke. 1994;25: 424-428.
10. Wiedermann JG, Marboe C, Schwartz A, Amols H, Weinberger J. Intracoronary irradiation reduces restenosis after balloon angioplasty in a porcine model. J Am Coll Cardiol. 1994;23:1491-1498.
11. Mazur W, Ali MN, Dabaghi SF, Cristead C, Abukhalil J, Parasdise P, DeFelice CA, Schulz D, Berner BM, Fajardo LF, French BA, Raizner AE. High dose rate intracoronary radiation suppresses neointimal proliferation in the stented and ballooned model of porcine restenosis. Circulation. 1994;90(suppl I):I-652. Abstract.
12. Waksman R, Robinson KA, Crocker IR, Gravanis MB, Cipolla GD, King SB III. Endovascular low-dose irradiation inhibits neointima formation after coronary artery balloon injury in swine: a possible role for radiation therapy in restenosis prevention. Circulation. 1995;91:1533-1539.
13. Wiedermann JG, Marboe C, Schwartz A, Amols H, Weinberger J. Intracoronary irradiation markedly reduces neointimal proliferation after balloon angioplasty in swine: persistent benefit at 6-month follow-up. J Am Coll Cardiol. 1995;25:1451-1456.
14. Liermann DD, Boettcher HD, Kollatch J, Schopol B, Strassman G, Strecker EP, Breddin KH. Prophylactic endovascular radiotherapy to prevent intimal hyperplasia after stent implantation in femoropopliteal arteries. Cardiovasc Intervent Radiol. 1994;17:12-16.
15. Karas SP, Gravanis MB, Santoian EC, Robinson KA, Anderberg K, King SB III. Coronary intimai proliferation after balloon injury and stenting in swine: an animal model of restenosis. J Am Coll Cardiol. 1992;20:467-474.
16. Gravanis MB, Robinson KA, Santoian EC, Schneider JE, King SB. The reparative phenomena at the site of balloon angioplasty in humans and experimental models. Cardiovasc Pathol. 1993;2: 263-273.
17. Gravanis MB, Roubin GS. Histopathologic phenomena at the site of percutaneous transluminal coronary angioplasty: the problem of restenosis. Hum Pathol. 1989;20:477-485.
18. Wanibuchi H, Ueda M, Dingemans KP, Becker AE. The response to percutaneous transluminal coronary angioplasty: an ultrastructural study of smooth muscle cells and endothelial cells. Cardiovasc Pathol. 1992;1:295-306.
19. Waksman R, Robinson KA, Sigman SR, Cipolla GD, King SB. Balloon overstretch injury correlates with neointima formation and not with vascular remodeling in the pig coronary restenosis model. J Am Coll Cardiol. 1994;138A. Abstract.
20. Halbleib JA, Mehlhorn TA. ITS: The Integrated TIGER Series of Coupled Electron/Photon Monte Carlo Transport Codes. CCC-467. Radiation Information Shielding Center, Oak Ridge National Laboratory.
21. Cross WG, Ing H, Freedman N. A short atlas of beta-ray spectra. Phys Med Biol. 1983;28(11):1251-1260.
22. Cascade PN, Peterson LE, Wajszczuk WJ, Mantel J. Radiation exposure to patients undergoing percutaneous transluminal coronary angioplasty. Am J Cardiol. 1987;59:996-997.
23. Pattee PL, Johns PC, Chambers RJ. Radiation risk to patients from percutaneous transluminal coronary angioplasty. J Am Coll Cardiol. 1993;22:1044-1051.
24. Jeans SP, Faulkner K, Love HG, Bardsley RA. An investigation of the radiation dose to staff during cardiac radiological studies. Br J Radiol. 1985;58:419-428.
25. Hehrlein C, Zimmerman M, Metz J, Fehsenfeld P, von Hodenberg E. Radioactive stent implantation inhibits neointimal proliferation in nonatherosclerotic rabbits. Circulation. 1993;88(suppl I):I-65. Abstract.
26. Fischell TA, Kharma BK, Fuschell DR, Loges PG, Coffey CW, Duggan DM, Naftilian AJ. Low dose β-particle emission from stent wire results in complete, localized inhibition of smooth muscle cell proliferation. Circulation. 1994;90:2956-2963.