Inhibition of endothelial nitric oxide synthase activity by protein kinase C

Hypertension

Volumn 25, Issue 2, 1995, Pages 180-185

  Hirata, Ken Ichi ^a   Kuroda, Ryohei ^a   Sakoda, Tsuyoshi ^a   Katayama, Masaya ^a   Inoue, Nobutaka ^a   Suematsu, Masakuni ^a   Kawashima, Seinosuke ^a   Yokoyama, Mitsuhiro ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

endothelium; nitric oxide; protein kinase C

Indexed keywords

8 BROMO CYCLIC GMP; ADENOSINE 5' O (3 THIOTRIPHOSPHATE); BUCLADESINE; CALCIMYCIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; STAUROSPORINE;

ANIMAL TISSUE; AORTA; ARTICLE; CATTLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

EID: 0028798319     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.25.2.180     Document Type: Article

References (38)

1. Palmer RMJ, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987;327:524-526.
2. Myers PR, Minor RL, Guerra R, Bates JN, Harrison DG. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide. Nature 1990;345:161-163.
3. Furchgott RF. Role of endothelium in responses of vascular smooth muscle. Circ Res. 1983;53:557-573.
4. Moncada S, Palmer RMJ, Higgs EA. Nitric Oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142.
5. Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature. 1988;333:664-666.
6. Nathan C. Nitric oxide as a secretory product of mammalian cells FASEB J. 1992;6:3051-3064.
7. Sessa WC, Harrison JK, Barber CM, Zeng D, Durieux ME, D'Angelo DD, Lynch KR, Peach MJ. Molecular cloning and expression of a cDNA encoding endothelial cell nitric oxide synthase. J Biol Chem. 1992;267:15274-15276.
8. Pollock JS, Förstermann U, Mitchell JA, Warner TD, Schmidt HHHW, Nakane M, Murad F. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc Natl Acad Sci U S A. 1991;88:10480-10484.
9. Lamas S, Marsden PA, Li GK, Tempst P, Michel T. Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc Natl Acad Sci U S A. 1992;89:6348-6352.
10. Janssens SP, Shimouchi A, Quertermous T, Bloch DB, Bloch KD. Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase. J Biol Chem. 1992;267:14519-14522.
11. Marsden PA, Schappert KT, Chen HS, Flowers M, Sundell CL, Wilcox JN, Lamas S, Michel T. Molecular cloning and characterization of human nitric oxide synthase. FEBS Lett. 1992;307:287-293.
12. Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J Clin Invest. 1992;90:2092-2096.
13. Bredt DS, Snyder SH. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme. Proc Natl Acad Sci U S A. 1990;87:682-685.
14. Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature. 1991;351:714-718.
15. Yui Y, Hattori R, Kosuga K, Eizawa H, Hiki K, Kawai C. Purification of nitric oxide synthase from rat macrophages. J Biol Chem. 1991;266:12544-12547.
16. Xie QW, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, Nathan C. Cloning and characterization of nitric oxide synthase from mouse macrophage. Science. 1992;256:225-228.
17. Lyons CR, Orloff GJ, Cunningham JM. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem. 1992;267:6370-6374.
18. Nunokawa Y, Ishida N, Tanaka S. Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 1993;191:89-94.
19. Geller DA, Lowenstein CJ, Shapiro RA, Nussler AK, Silvio MD, Wang SC, Nakayama DK, Simmons RL, Snyder SH, Billiar TR. Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc Natl Acad Sci U S A. 1993;90:3491-3495.
20. Berridge MJ, Irvine RF. Inositol triphosphate, a novel second messenger in cellular signal transduction. Nature. 1984;312:315-321.
21. Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature. 1984;308:693-698.
22. Bredt DS, Ferris CD, Snyder SH. Nitric oxide synthase regulatory sites: phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase: identification of flavin and calmodulin binding sites. J Biol Chem. 1992;267:10976-10981.
23. Reimann EM, Beham RA. Purification and properties of specific protein kinases: catalytic subunit of cAMP-dependent protein kinase. Methods Enzymol. 1983;99:51-55.
24. Ryan US, Mortara M, Whitaker C. Methods for microcarrier culture of bovine pulmonary artery endothelial cells avoiding the use of enzyme. Tissue Cell. 1980;12:619-635.
25. Hirata K, Akita H, Yokoyama M. Oxidized low density lipoprotein inhibits bradykinin-induced phosphoinositide hydrolysis in cultured bovine endothelial cells. FEBS Lett. 1991;287:181-184.
26. Inoue N, Hirata K, Yamada M, Hamamori Y, Matsuda Y, Akita H, Yokoyama M. Lysophosphatidylcholine inhibits bradykinin-induced phosphoinositide hydrolysis and calcium transients in cultured bovine aortic endothelial cells. Circ Res. 1992;71:1410-1421.
27. Ohashi Y, Katayama M, Hirata K, Suematsu M, Kawashima S, Yokoyama M. Activation of nitric oxide synthase from cultured aortic endothelial cells by phospholipids. Biochem Biophys Res Commun. 1993;195:1314-1320.
28. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
29. Cox RD. Determination of nitrate and nitrite at the parts per billion level by chemiluminescence. Anal Chem. 1980;52:332-335.
30. Myers PR, Guerra R, Harrison DG. Release of NO and EDRF from cultured bovine aortic endothelial cells. Am J Physiol 1989;256:H1030-H1037.
31. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-254.
32. Brock TA, Capasso EA. Thrombin and histamine activate phospholipase C in human endothelial cells via a phorbol ester-sensitive pathway. J Cell Physiol. 1988;136:54-62.
33. 2+. Biochem J. 1989;262:431-437.
34. Weinheimer G, Wagner B, Osswald H. Interference of phorbol esters with endothelium-dependent vascular smooth muscle relaxation. Eur J Pharmacol. 1986;130:319-322.
35. Lewis MJ, Henderson AH. A phorbol ester inhibits the release of endothelium-derived relaxing factor. Eur J Pharmacol. 1987;137:167-171.
36. Rubanyi GM, Desiderio D, Luisi A, Johns A, Sybertz EJ. Phorbol dibutyrate inhibits release and action of endothelium-derived relaxing factor(s) in canine blood vessels. J Pharmacol Exp Ther. 1989;249:858-863.
37. Matsubara T, Ziff M. Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore. J Cell Physiol. 1986;127:207-210.
38. Smith JA, Lang D. Release of endothelium-derived relaxing factor from pig cultured aortic endothelial cells, as assessed by changes in endothelial cell cyclic GMP content, is inhibited by a phorbol ester Br J Pharmacol. 1990;99:565-571.