DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases

Molecular and Cellular Biology

Volumn 15, Issue 2, 1995, Pages 1102-1109

  Röche, Serge ^a   Koegl, Manfred ^a   Barone, M Vittoria ^a   Roussel, Martine F ^b   Courtneidge, Sara A ^a,c  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c SUGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN TYROSINE KINASE;

ARTICLE; CELL CYCLE S PHASE; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; MITOGENESIS; PRIORITY JOURNAL;

EID: 0028795721     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.15.2.1102     Document Type: Article

References (35)

1. Ansorge, W., and R. Pepperkok. 1988. Performance of an automated system for capillary microinjection into living cells. J. Biochem. Biophys. Methods 16:283-292.
2. Cantley, L. C. Personal communication.
3. Cantley, L. C., K. R. Auger, C. Carpenter, B. Duckworth, A. Graziani, R. Kapeller, and S. Soltoff. 1991. Oncogenes and signal transduction. Cell 64:281-302.
4. Courtneidge, S. A. 1994. Protein tyrosine kinases, with emphasis on the Src family. Semin. Cancer Biol. 5:239-246.
5. Courtneidge, S. A., R. Dhand, D. Pilat, G. M. Twamley, M. D. Waterfield, and M. Roussel. 1993. Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor. EMBO J. 12:943-950.
6. c-src and increases its protein-tyrosine kinase activity. Mol. Cell. Biol. 8:3345-3356.
7. Hordijk, P. L., I. Verlaan, E. J. van Corven, and W. H. Moolenaar. 1994. Protein tyrosine phosphorylation induced by lysophosphatidic acid in rat-1 fibroblasts. J. Biol. Chem. 269:645-651.
8. Jalink, K., T. Eichholtz, F. R. Postma, E. J. van Corven, and W. H. Moolenaar. 1993. Lysophosphatidic acid induces neuronal shape changes via a novel, receptor-mediated signaling pathway: similarity to thrombin action. Cell Growth Differ. 4:247-255.
9. c-src can induce focus formation without complete transformation of NIH 3T3 fibroblasts. Mol. Cell. Biol. 5:1073-1083.
10. Kazlauskas, A., A. Kashishian, J. A. Cooper, and M. Valius. 1992. GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor β subunit. Mol. Cell. Biol. 12:2534-2544.
11. Koegl, M., R. M. Kypta, M. Bergman, K. Alitalo, and S. A. Courtneidge. 1994. Rapid and efficient purification of Src homology 2 domain-containing proteins: Fyn, Csk, and phosphatidylinositol 3-kinase p85. Biochem. J. 302: 737-744.
12. Kumagai, N., N. Morii, K. Fujisawa, T. Yoshimasa, K. Nakao, and S. Narumiya. 1993. Lysophosphatidic acid induces tyrosine phosphorylation and activation of MAP-kinase and focal adhesion kinase in cultured Swiss 3T3 fibroblasts. FEBS Lett. 329:273-276.
13. Kypta, R. M., Y. Goldberg, E. T. Ulug, and S. A. Courtneidge. 1990. Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell 62:481-492.
14. Leeb-Lundberg, F., and X.-H. Song. 1991. Bradykinin and bombesin rapidly simulate tyrosine phosphorylation of a 120-kDa group of proteins in Swiss 3T3 cells. J. Biol. Chem. 266:7746-7749.
15. c-src with two major signaling pathways in human breast cancer. Proc. Natl. Acad. Sci. USA 91:83-87.
16. c-src. Mol. Cell. Biol. 8:497-501.
17. Mori, S., L. Rönnstrand, K. Yokote, A. Engström, S. A. Courtneidge, L. Claesson-Welsh, and C.-H. Heldin. 1993. Identification of two juxtamembrane autophosphorylation sites in the PDGF β-receptor. Involvement in the interaction with Src family tyrosine kinases. EMBO J. 12:2257-2264.
18. Nishimura, R., W. L. Kashishian, A. Mondino, M. Zhou, J. Cooper, and J. Schlessinger. 1993. Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor. Mol. Cell. Biol. 13:6889-6896.
19. Pawson, T., and J. Schlessinger. 1993. SH2 and SH3 domains. Curr. Biol. 3:434-442.
20. Ralston, R., and J. M. Bishop. 1985. The product of the proto-oncogene c-src is modified during the cellular response to platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 82:7845-7849.
21. Reedijk, M., X. Liu, and T. Pawson. 1990. Interactions of phosphatidylinositol kinase, GTPase-activating protein (GAP), and GAP-associated proteins with the colony-stimulating factor 1 receptor. Mol. Cell. Biol. 10:5601-5608.
22. Roche, S., M. Koegl, and S. A. Courtneidge. 1994. The phosphatidylinositol 3-kinase α is required for DNA synthesis induced by some, but not, all growth factors. Proc. Natl. Acad. Sci. USA 91:9185-9189.
23. Roussel, M. F., T. J. Dull, C. W. Rettenmier, P. Ralph, A. Ullrich, and C. J. Sherr. 1987. Transforming potential of the c-fms proto-oncogene (CSF-1 receptor). Nature (London) 325:549-552.
24. Roussel, M. F., S. A. Shurtleff, J. R. Downing, and C. J. Sherr. 1990. A point mutation at tyrosine 809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of fos and junB genes. Proc. Natl. Acad. Sci. USA 87:6738-6742.
25. Seckl, M., and E. Rozengurt. 1993. Tyrphostin inhibits bombesin stimulation of tyrosine phosphorylation, c-fos expression, and DNA synthesis in Swiss 3T3 cells. J. Biol. Chem. 268:9548-9554.
26. Shurtleff, S. A., J. R. Downing, C. O. Rock, S. A. Hawkins, M. F. Roussel, and C. Sherr. 1990. Structural features of the colony-stimulating factor 1 receptor that affect its association with phosphatidylinositol 3-kinase. EMBO J. 9:2415-2421.
27. Songyang, Z., S. E. Shoelson, M. Chaudhuri, G. Gish, T. Pawson, W. G. Haser, F. King, T. Roberts, S. Ralnofsky, R. J. Lechleider, B. G. Neel, R. B. Birge, J. E. Fajardo, M. M. Chou, H. Hanafusa, B. Schaffhausen, and L. C. Cantley. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell 72:767-778.
28. Twamley, G., B. Hall, R. Kypta, and S. A. Courtneidge. 1992. Association of Fyn with the activated PDGF receptor: requirements for binding and phosphorylation. Oncogene 7:1893-1901.
29. Twamley-Stein, G. M., R. Pepperkok, W. Ansorge, and S. A. Courtneidge. 1993. The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH-3T3 cells. Proc. Natl. Acad. Sci. USA 90:7696-7700.
30. van der Geer, P., and T. Hunter. 1993. Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 12: 5161-5172.
31. Varticovski, L., B. Druker, D. Morrison, L. Cantley, and T. Roberts. 1989. The colony stimulating factor-1 receptor associates with an activated phosphatidylinositol 3-kinase. Nature (London) 342:699-702.
32. Wennström, S., A. Siegbahn, K. Yokote, A.-K. Arvidsson, C.-H. Heldin, S. Mori, and L. Claesson-Welsh. 1994. Membrane ruffling and chemotaxis transduced by the PDGF β-receptor require the binding site for phosphatidylinositol 3′ kinase. Oncogene 9:651-660.
33. c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src. Mol. Cell. Biol. 9:1536-1544.
34. Zachary, I., J. Gil, W. Lehmann, J. Sinnett-Smith, and E. Rozengurt. 1991. Bombesin, vasopressin, and endothelin rapidly stimulated tyrosine phosphorylation in intact Swiss 3T3 cells. Proc. Natl. Acad. Sci. USA 88:4577-4581.
35. Zachary, I., J. Sinnett-Smith, and E. Rozengurt. 1992. Bombesin, vasopressin and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate. J. Biol. Chem. 267:19031-19034.