Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice

Neuroscience Letters

Volumn 199, Issue 1, 1995, Pages 1-4

  Gordon, Irit ^a   Grauer, Ettie ^b   Genis, Idit ^a   Sehayek, Ephraim ^c   Michaelson, Daniel M ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

Author keywords

Apolipoprotein E; Cholinergic nervous system; Memory; Mice

Indexed keywords

ACETYLCHOLINE; APOLIPOPROTEIN E; CHOLINE ACETYLTRANSFERASE; OXOTREMORINE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; FRONTAL CORTEX; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; KNOCK OUT MOUSE; MALE; MAZE TEST; MEMORY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; APOLIPOPROTEINS E; AUTONOMIC NERVOUS SYSTEM DISEASES; BRAIN; CHOLINE O-ACETYLTRANSFERASE; COGNITION DISORDERS; FRONTAL LOBE; HIPPOCAMPUS; HYPOTHERMIA, INDUCED; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, KNOCKOUT; MUSCARINIC AGONISTS; OXOTREMORINE; PARASYMPATHETIC NERVOUS SYSTEM; SUPPORT, NON-U.S. GOV'T;

EID: 0028790904     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(95)12006-P     Document Type: Article

References (18)

1. The cholinergic hypothesis of geriatric memory dysfunction: a critical review
2. Differential effects of cholinergic blockade on performance of rats in the water tank navigation task and in radial water maze
3. Alzheimer's disease: a disorder of cortical cholinergic innervation
4. Thermoregulatory behavior in Alzheimer's disease
5. Chronic inescapable footshock produces cholinergic system supersensitivity
6. A rapid radiochemical method for the determination of choline acetyltransferase
7. Phosphorylation of tau in apolipoprotein E deficient mice
8. Differential effects of anticholinergic drugs on paired discrimination performance
9. 695 transgenic and apoE knockout mice
10. Abnormal synaptic regeneration in hAPP transgenic and apoE knockout mice
11. Developments of a water-maze procedure for studying spatial learning in the rat
12. Hippocampal function and memory for temporal context
13. Basal forebrain cholinergic system: a functional analysis
14. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
15. Apolipoprotein E in animal models of CNS injury in Alzheimer's disease
16. Lower cognitive performance in normal older adult male twins carrying the apolipoprotein E epsilon 4 allele
17. Apolipoprotein E affects the rate of Alzheimer's disease expression: β-amyloid burden is a secondary consequence dependent on ApoE genotype and duration of disease
18. A severe loss of choline acetyltransferase in the frontal cortex of Alz heimer patients carrying apolipoprotein E4 allele