메뉴 건너뛰기




Volumn 60, Issue 7, 1995, Pages 695-702

Alloantigen priming after total lymphoid irradiation alters alloimmune cytokine responses

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4;

EID: 0028787491     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199510150-00014     Document Type: Article
Times cited : (29)

References (71)
  • 1
    • 0018118256 scopus 로고
    • Induction and mechanism of tolerance to bovine serum albumin in mice given total lymphoid irradiation (TLI)
    • Zan-Bar I, Slavin S, Strober S. Induction and mechanism of tolerance to bovine serum albumin in mice given total lymphoid irradiation (TLI). J Immunol 1978; 121: 1402.
    • (1978) J Immunol , vol.121 , pp. 1402
    • Zan-Bar, I.1    Slavin, S.2    Strober, S.3
  • 2
    • 0017644914 scopus 로고
    • Induction of specific tissue transplantation tolerance by using fractionated total lymphoid irradiation in adult mice: Long-term survival of allogeneic bone marrow and skin grafts
    • Slavin S, Strober S, Fuks Z, Kaplan HS. Induction of specific tissue transplantation tolerance by using fractionated total lymphoid irradiation in adult mice: long-term survival of allogeneic bone marrow and skin grafts. J Exp Med 1977; 146: 43.
    • (1977) J Exp Med , vol.146 , pp. 43
    • Slavin, S.1    Strober, S.2    Fuks, Z.3    Kaplan, H.S.4
  • 3
    • 0021326371 scopus 로고
    • Influence of radiation field and fractionation schedule of total lymphoid irradiation (TLI) on the induction of suppressor cells and stable chimerism after bone marrow transplantation in mice
    • Waer M, Ang KK, van der Schueren E, Vandeputte M. Influence of radiation field and fractionation schedule of total lymphoid irradiation (TLI) on the induction of suppressor cells and stable chimerism after bone marrow transplantation in mice. J Immunol 1984; 132: 985.
    • (1984) J Immunol , vol.132 , pp. 985
    • Waer, M.1    Ang, K.K.2    Van der Schueren, E.3    Vandeputte, M.4
  • 4
    • 0027214166 scopus 로고
    • Nondeletional mechanisms of tolerance in total-lymphoid irradiation-induced bone marrow chimeras
    • Field EH, Steinmuller D. Nondeletional mechanisms of tolerance in total-lymphoid irradiation-induced bone marrow chimeras. Transplantation 1993; 56: 250.
    • (1993) Transplantation , vol.56 , pp. 250
    • Field, E.H.1    Steinmuller, D.2
  • 5
    • 0018130249 scopus 로고
    • Transplantation tolerance in adult rats using total lymphoid irradiation (TLI): Permanent survival of skin, heart, and marrow allografts
    • Slavin S, Reitz B, Bieber CP, Kaplan HS, Strober S. Transplantation tolerance in adult rats using total lymphoid irradiation (TLI): permanent survival of skin, heart, and marrow allografts. J Exp Med 1978; 147: 700.
    • (1978) J Exp Med , vol.147 , pp. 700
    • Slavin, S.1    Reitz, B.2    Bieber, C.P.3    Kaplan, H.S.4    Strober, S.5
  • 6
    • 0025168817 scopus 로고
    • Canine pancreas and kidney transplantation following total lymphoid irradiation
    • Williamson P, Allen RD, Deane SA, et al. Canine pancreas and kidney transplantation following total lymphoid irradiation. Transplantation 1990; 50: 576.
    • (1990) Transplantation , vol.50 , pp. 576
    • Williamson, P.1    Allen, R.D.2    Deane, S.A.3
  • 7
    • 0024554610 scopus 로고
    • Cardiac allograft prolongation in mice treated with combined posttransplantation total lymphoid irradiation and anti-L3T4 antibody therapy
    • Trager DK, Banks BA, Rosenbaum GE, et al. Cardiac allograft prolongation in mice treated with combined posttransplantation total lymphoid irradiation and anti-L3T4 antibody therapy. Transplantation 1989; 47: 587.
    • (1989) Transplantation , vol.47 , pp. 587
    • Trager, D.K.1    Banks, B.A.2    Rosenbaum, G.E.3
  • 8
    • 0027748186 scopus 로고
    • Induction of tolerance to heart allografts in rats using posttransplant total lymphoid irradiation and anti-T cell antibodies
    • Woodley SL, Gurley KE, Hoffmann SL, et al. Induction of tolerance to heart allografts in rats using posttransplant total lymphoid irradiation and anti-T cell antibodies. Transplantation 1993; 56: 1443.
    • (1993) Transplantation , vol.56 , pp. 1443
    • Woodley, S.L.1    Gurley, K.E.2    Hoffmann, S.L.3
  • 9
    • 0028270077 scopus 로고
    • Nonspecific mixed lymphocyte culture inhibitory antibodies in sera of tolerant transplanted baboons conditioned with total lymphoid irradiation
    • Stark JH, Smit JA, Myburgh JA. Nonspecific mixed lymphocyte culture inhibitory antibodies in sera of tolerant transplanted baboons conditioned with total lymphoid irradiation. Transplantation 1994; 57: 1103.
    • (1994) Transplantation , vol.57 , pp. 1103
    • Stark, J.H.1    Smit, J.A.2    Myburgh, J.A.3
  • 10
    • 0023764096 scopus 로고
    • Use of cyclophosphamide and total lymphoid irradiation combined with cyclosporine in bone marrow transplantation for transfused severe aplastic anemia
    • Miyamura K, Kojima S, Takeyama K, et al. Use of cyclophosphamide and total lymphoid irradiation combined with cyclosporine in bone marrow transplantation for transfused severe aplastic anemia. Bone Marrow Transplant 1988; 3: 457.
    • (1988) Bone Marrow Transplant , vol.3 , pp. 457
    • Miyamura, K.1    Kojima, S.2    Takeyama, K.3
  • 11
    • 0024551210 scopus 로고
    • Total lymphoid irradiation preceding bone marrow transplantation for chronic myeloid leukaemia
    • James ND, Apperley JF, Kam KC, et al. Total lymphoid irradiation preceding bone marrow transplantation for chronic myeloid leukaemia. Clin Radiol 1989; 40: 195.
    • (1989) Clin Radiol , vol.40 , pp. 195
    • James, N.D.1    Apperley, J.F.2    Kam, K.C.3
  • 12
    • 0025924216 scopus 로고
    • Total lymphoid irradiation to prevent graft rejection in recipients of HLA non-identical T cell-depleted allogeneic marrow
    • Soiffer RJ, Mauch P, Tarbell NJ, et al. Total lymphoid irradiation to prevent graft rejection in recipients of HLA non-identical T cell-depleted allogeneic marrow. Bone Marrow Transplant 1991; 7: 23.
    • (1991) Bone Marrow Transplant , vol.7 , pp. 23
    • Soiffer, R.J.1    Mauch, P.2    Tarbell, N.J.3
  • 13
    • 0024806021 scopus 로고
    • Total lymphoid irradiation in heart transplantation: Adjunctive treatment for recurrent rejection
    • Frist WH, Winterland AW, Gerhardt EB, et al. Total lymphoid irradiation in heart transplantation: adjunctive treatment for recurrent rejection. Ann Thorac Surg 1989; 48: 863.
    • (1989) Ann Thorac Surg , vol.48 , pp. 863
    • Frist, W.H.1    Winterland, A.W.2    Gerhardt, E.B.3
  • 14
    • 0025903692 scopus 로고
    • Total lymphoid irradiation for treatment of intractable cardiac allograft rejection
    • Hunt SA, Strober S, Hoppe RT, Stinson EB. Total lymphoid irradiation for treatment of intractable cardiac allograft rejection. J Heart Lung Transplant 1991; 10: 211.
    • (1991) J Heart Lung Transplant , vol.10 , pp. 211
    • Hunt, S.A.1    Strober, S.2    Hoppe, R.T.3    Stinson, E.B.4
  • 15
    • 0026806292 scopus 로고
    • Total lymphoid irradiation in the treatment of early or recurrent heart rejection
    • Salter MM, Kirklin JK, Bourge RC, et al. Total lymphoid irradiation in the treatment of early or recurrent heart rejection. J Heart Lung Transplant 1992; 11: 902.
    • (1992) J Heart Lung Transplant , vol.11 , pp. 902
    • Salter, M.M.1    Kirklin, J.K.2    Bourge, R.C.3
  • 16
    • 0026647945 scopus 로고
    • Total lymphoid irradiation: A novel and successful therapy for resistant cardiac allograft rejection
    • Evans MA, Schomberg PJ, Rodeheffer RJ, et al. Total lymphoid irradiation: a novel and successful therapy for resistant cardiac allograft rejection. Mayo Clin Proc 1992; 67: 785.
    • (1992) Mayo Clin Proc , vol.67 , pp. 785
    • Evans, M.A.1    Schomberg, P.J.2    Rodeheffer, R.J.3
  • 17
    • 0024038869 scopus 로고
    • Renal cadaveric transplantation in diabetics using total lymphoid irradiation or cyclosporin A. A controlled randomized study. Leuven Collaborative Transplantation Group
    • Waer M, Vanrenterghem Y, Roels L, et al. Renal cadaveric transplantation in diabetics using total lymphoid irradiation or cyclosporin A. A controlled randomized study. Leuven Collaborative Transplantation Group. Transpl Int 1988; 1: 64.
    • (1988) Transpl Int , vol.1 , pp. 64
    • Waer, M.1    Vanrenterghem, Y.2    Roels, L.3
  • 18
    • 0025833612 scopus 로고
    • Total lymphoid irradiation in clinical renal transplantation—results in 73 patients
    • Myburgh JA, Meyers AM, Margolius L, et al. Total lymphoid irradiation in clinical renal transplantation—results in 73 patients. Transplant Proc 1991; 23: 2033.
    • (1991) Transplant Proc , vol.23 , pp. 2033
    • Myburgh, J.A.1    Meyers, A.M.2    Margolius, L.3
  • 19
    • 0027415825 scopus 로고
    • Eight-year actuarial graft and patient survival of kidney transplants in highly immunized recipients pretreated with total lymphoid irradiation: A single-center experience
    • Molajoni ER, Bachetoni A, Cinti P, et al. Eight-year actuarial graft and patient survival of kidney transplants in highly immunized recipients pretreated with total lymphoid irradiation: a single-center experience. Transplant Proc 1993; 25: 776.
    • (1993) Transplant Proc , vol.25 , pp. 776
    • Molajoni, E.R.1    Bachetoni, A.2    Cinti, P.3
  • 20
    • 0024364744 scopus 로고
    • Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation
    • Strober S, Dhillon M, Schubert M, et al. Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation. N Engl J Med 1989; 321: 28.
    • (1989) N Engl J Med , vol.321 , pp. 28
    • Strober, S.1    Dhillon, M.2    Schubert, M.3
  • 21
    • 0023269447 scopus 로고
    • Renal transplant patients treated with total lymphoid irradiation show specific unresponsiveness to donor antigens the mixed leukocyte reaction (MLR)
    • Chow D, Saper V, Strober S. Renal transplant patients treated with total lymphoid irradiation show specific unresponsiveness to donor antigens the mixed leukocyte reaction (MLR). J Immunol 1987; 138: 3746.
    • (1987) J Immunol , vol.138 , pp. 3746
    • Chow, D.1    Saper, V.2    Strober, S.3
  • 22
    • 0021558066 scopus 로고
    • Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: Exploring obscure relationships
    • Strober S. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol 1984; 2: 219.
    • (1984) Annu Rev Immunol , vol.2 , pp. 219
    • Strober, S.1
  • 24
    • 0021347730 scopus 로고
    • Natural suppressor (NS) cells found in the spleen of neonatal mice and adult mice given total lymphoid irradiation (TLI) express the null surface phenotype
    • Oseroff A, Okada S, Strober S. Natural suppressor (NS) cells found in the spleen of neonatal mice and adult mice given total lymphoid irradiation (TLI) express the null surface phenotype. J Immunol 1984; 132: 101.
    • (1984) J Immunol , vol.132 , pp. 101
    • Oseroff, A.1    Okada, S.2    Strober, S.3
  • 25
    • 0019983814 scopus 로고
    • Spleen cells from adult mice given total lymphoid irradiation or from newborn mice have similar regulatory effects in the mixed leukocyte reaction. I. Generation of antigen-specific suppressor cells in the mixed leukocyte reaction after the addition of spleen cells from adult mice given total lymphoid irradiation
    • Okada S, Strober S. Spleen cells from adult mice given total lymphoid irradiation or from newborn mice have similar regulatory effects in the mixed leukocyte reaction. I. Generation of antigen-specific suppressor cells in the mixed leukocyte reaction after the addition of spleen cells from adult mice given total lymphoid irradiation. J Exp Med 1982; 156: 522.
    • (1982) J Exp Med , vol.156 , pp. 522
    • Okada, S.1    Strober, S.2
  • 26
    • 0024465501 scopus 로고
    • The immunosuppressive mechanism of total lymphoid irradiation. I. The effect on IL-2 production and IL-2 receptor expression
    • Field EH, Becker GC. The immunosuppressive mechanism of total lymphoid irradiation. I. The effect on IL-2 production and IL-2 receptor expression. Transplantation 1989; 48: 499.
    • (1989) Transplantation , vol.48 , pp. 499
    • Field, E.H.1    Becker, G.C.2
  • 27
    • 0021878316 scopus 로고
    • Cloned natural suppressor cell lines derived from the spleens of neonatal mice
    • Schwadron RB, Gandour DM, Strober S. Cloned natural suppressor cell lines derived from the spleens of neonatal mice. J Exp Med 1985; 162: 297.
    • (1985) J Exp Med , vol.162 , pp. 297
    • Schwadron, R.B.1    Gandour, D.M.2    Strober, S.3
  • 28
    • 0021691109 scopus 로고
    • In vitro propagation and cloning of murine natural suppressor (NS) cells
    • Hertel-Wulff B, Okada S, Oseroff A, Strober S. In vitro propagation and cloning of murine natural suppressor (NS) cells. J Immunol 1984; 133: 2791.
    • (1984) J Immunol , vol.133 , pp. 2791
    • Hertel-Wulff, B.1    Okada, S.2    Oseroff, A.3    Strober, S.4
  • 29
    • 0024361199 scopus 로고
    • Cloned natural suppressor cell lines express the CD3+CD4-CD8- surface phenotype and the alpha, beta heterodimer of the T cell antigen receptor
    • Strober S, Dejbachsh-Jones S, VanVlasselaer P, Duwe G, Salimi S, Allison JP. Cloned natural suppressor cell lines express the CD3+CD4-CD8- surface phenotype and the alpha, beta heterodimer of the T cell antigen receptor. J Immunol 1989; 143: 1118.
    • (1989) J Immunol , vol.143 , pp. 1118
    • Strober, S.1    Dejbachsh-Jones, S.2    VanVlasselaer, P.3    Duwe, G.4    Salimi, S.5    Allison, J.P.6
  • 30
    • 0028922933 scopus 로고
    • Enhanced type-2 and diminished type-1 cytokines in neonatal tolerance
    • Chen N, Field EH. Enhanced type-2 and diminished type-1 cytokines in neonatal tolerance. Transplantation 1995; 59: 933.
    • (1995) Transplantation , vol.59 , pp. 933
    • Chen, N.1    Field, E.H.2
  • 31
    • 0026729563 scopus 로고
    • Heart allografts in murine systems. The differential activation of Th2-like effector cells in peripheral tolerance
    • Takeuchi T, Lowry RP, Konieczny B. Heart allografts in murine systems. The differential activation of Th2-like effector cells in peripheral tolerance. Transplantation 1992; 53: 1281.
    • (1992) Transplantation , vol.53 , pp. 1281
    • Takeuchi, T.1    Lowry, R.P.2    Konieczny, B.3
  • 32
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, Hafler D, Weiner H. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994; 265: 1237.
    • (1994) Science , vol.265 , pp. 1237
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.4    Weiner, H.5
  • 33
    • 0027207375 scopus 로고
    • Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a Th2 phenomenon?
    • Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a Th2 phenomenon? Immunol Today 1993; 14: 353.
    • (1993) Immunol Today , vol.14 , pp. 353
    • Wegmann, T.G.1    Lin, H.2    Guilbert, L.3    Mosmann, T.R.4
  • 34
    • 0027324854 scopus 로고
    • Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation
    • Hancock WW, Sayegh MH, Kwok CA, Weiner HL, Carpenter CB. Oral, but not intravenous, alloantigen prevents accelerated allograft rejection by selective intragraft Th2 cell activation. Transplantation 1993; 55: 1112.
    • (1993) Transplantation , vol.55 , pp. 1112
    • Hancock, W.W.1    Sayegh, M.H.2    Kwok, C.A.3    Weiner, H.L.4    Carpenter, C.B.5
  • 35
    • 0024365893 scopus 로고
    • Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation
    • Bass H, Mosmann T, Strober S. Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation. J Exp Med 1989; 170: 1495.
    • (1989) J Exp Med , vol.170 , pp. 1495
    • Bass, H.1    Mosmann, T.2    Strober, S.3
  • 36
    • 0026663510 scopus 로고
    • Altered IFN-γ and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody
    • Field EH, Rouse TM, Fleming AL, Jamali I, Cowdery JS. Altered IFN-γ and IL-4 pattern lymphokine secretion in mice partially depleted of CD4 T cells by anti-CD4 monoclonal antibody. J Immunol 1992; 149: 1131.
    • (1992) J Immunol , vol.149 , pp. 1131
    • Field, E.H.1    Rouse, T.M.2    Fleming, A.L.3    Jamali, I.4    Cowdery, J.S.5
  • 37
    • 0025275036 scopus 로고
    • Detection of individual mouse splenic T cells producing IFN-γ and IL-5 using the enzyme-linked immunospot (ELISPOT) assay
    • Taguchi T, McGhee JR, Coffman RL, et al. Detection of individual mouse splenic T cells producing IFN-γ and IL-5 using the enzyme-linked immunospot (ELISPOT) assay. J Immunol Methods 1990; 128: 65.
    • (1990) J Immunol Methods , vol.128 , pp. 65
    • Taguchi, T.1    McGhee, J.R.2    Coffman, R.L.3
  • 38
    • 0023228892 scopus 로고
    • Alloantigen persistence in induction and maintenance of transplantation tolerance
    • Morecki S, Leshem B, Eid A, Slavin S. Alloantigen persistence in induction and maintenance of transplantation tolerance. J Exp Med 1987; 165: 1468.
    • (1987) J Exp Med , vol.165 , pp. 1468
    • Morecki, S.1    Leshem, B.2    Eid, A.3    Slavin, S.4
  • 39
    • 0025674112 scopus 로고
    • Induction of tolerance in peripheral T cells with monoclonal antibodies
    • Qin S, Wise M, Cobbold SP, et al. Induction of tolerance in peripheral T cells with monoclonal antibodies. Eur J Immunol 1990; 20: 2737.
    • (1990) Eur J Immunol , vol.20 , pp. 2737
    • Qin, S.1    Wise, M.2    Cobbold, S.P.3
  • 40
    • 0018818630 scopus 로고
    • Transplantation tolerance in primates after total lymphoid irradiation and allogeneic bone marrow injection. III. Lymphocyte responsiveness and suppressor cell activity
    • Smit, JA, Hill RRH, Myburgh JA, Browde S. Transplantation tolerance in primates after total lymphoid irradiation and allogeneic bone marrow injection. III. Lymphocyte responsiveness and suppressor cell activity. Transplantation 1980; 30: 107.
    • (1980) Transplantation , vol.30 , pp. 107
    • Smit, J.A.1    Hill, R.R.H.2    Myburgh, J.A.3    Browde, S.4
  • 41
    • 0026517629 scopus 로고
    • + memory T cells from the spleen lack MEL-14, the lymph node homing receptor
    • + memory T cells from the spleen lack MEL-14, the lymph node homing receptor. J Immunol 1992; 148: 324.
    • (1992) J Immunol , vol.148 , pp. 324
    • Bradley, L.M.1    Atkins, G.G.2    Swain, S.3
  • 42
    • 0027133667 scopus 로고
    • Regulatory role of IL4 and other cytokines in T helper cell development in an αβTCR transgenic mouse system
    • O’Garra A, Macatonia SE, Hsieh C, Murphy KM. Regulatory role of IL4 and other cytokines in T helper cell development in an αβTCR transgenic mouse system. Res Immunol 1993; 144:620.
    • (1993) Res Immunol , vol.144 , pp. 620
    • O’Garra, A.1    Macatonia, S.E.2    Hsieh, C.3    Murphy, K.M.4
  • 44
    • 0026710184 scopus 로고
    • IL-4 plays a dominant role in the differential development of ThO into Th1 and Th2 cells
    • Abehsira-Amar O, Gibert M, Joliy M, Theze J, Jankovic DL. IL-4 plays a dominant role in the differential development of ThO into Th1 and Th2 cells. J Immunol 1992; 148: 3820.
    • (1992) J Immunol , vol.148 , pp. 3820
    • Abehsira-Amar, O.1    Gibert, M.2    Joliy, M.3    Theze, J.4    Jankovic, D.L.5
  • 45
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain SL, Weinberg AD, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol 1990; 145: 3796.
    • (1990) J Immunol , vol.145 , pp. 3796
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, G.4
  • 46
    • 0025082313 scopus 로고
    • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • LeGros G, Ben Sasson SZ, Seder R, Finkelman FD, Paul WE. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Exp Med 1990; 172: 921.
    • (1990) J Exp Med , vol.172 , pp. 921
    • LeGros, G.1    Ben Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.E.5
  • 48
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989; 170: 2081.
    • (1989) J Exp Med , vol.170 , pp. 2081
    • Fiorentino, D.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 50
    • 0023622458 scopus 로고
    • Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies
    • Cherwinski HM, Schumacher JH, Brown KD, Mosmann TR. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J Exp Med 1987; 166: 1229.
    • (1987) J Exp Med , vol.166 , pp. 1229
    • Cherwinski, H.M.1    Schumacher, J.H.2    Brown, K.D.3    Mosmann, T.R.4
  • 51
    • 0026056142 scopus 로고
    • IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis
    • Scott P. IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J Immunol 1991; 147: 3149.
    • (1991) J Immunol , vol.147 , pp. 3149
    • Scott, P.1
  • 52
    • 0024357498 scopus 로고
    • Antiproliferative effect of IFN-γ in immune regulation. III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ
    • Gajewski TF, Joyce J, Fitch FW. Antiproliferative effect of IFN-γ in immune regulation. III. Differential selection of Th1 and Th2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ. J Immunol 1989; 143: 15.
    • (1989) J Immunol , vol.143 , pp. 15
    • Gajewski, T.F.1    Joyce, J.2    Fitch, F.W.3
  • 53
    • 0023748914 scopus 로고
    • Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells
    • Femandez-Botran R, Sanders VM, Mosmann TR, Vitetta ES. Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med 1988; 168: 543.
    • (1988) J Exp Med , vol.168 , pp. 543
    • Femandez-Botran, R.1    Sanders, V.M.2    Mosmann, T.R.3    Vitetta, E.S.4
  • 55
    • 0028020588 scopus 로고
    • Generation of polarized antigen-specific CD8 effector populations: Reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles
    • Croft M, Carter L, Swain SL, Dutton RW. Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med 1994; 180: 1715.
    • (1994) J Exp Med , vol.180 , pp. 1715
    • Croft, M.1    Carter, L.2    Swain, S.L.3    Dutton, R.W.4
  • 56
    • 0027141892 scopus 로고
    • Developmental regulation of IL-4, IL-2, and IFN-γ production by murine peripheral T lymphocytes
    • Adkins B, Ghanei A, Hamilton K. Developmental regulation of IL-4, IL-2, and IFN-γ production by murine peripheral T lymphocytes. J Immunol 1993; 151: 6617.
    • (1993) J Immunol , vol.151 , pp. 6617
    • Adkins, B.1    Ghanei, A.2    Hamilton, K.3
  • 57
    • 0025886982 scopus 로고
    • + T cells acquire specific lymphokine secretion potentials during thymic maturation
    • + T cells acquire specific lymphokine secretion potentials during thymic maturation. Nature 1991; 353: 68.
    • (1991) Nature , vol.353 , pp. 68
    • Bendelac, A.1    Schwartz, R.H.2
  • 58
    • 0028167459 scopus 로고
    • “Anergy” of Th0 helper T lymphocytes induces downregulation of Thl characteristics and a transition of a Th2-like phenotype
    • Gajewski TF, Lancki DW, Stack R, Fitch FW. “Anergy” of Th0 helper T lymphocytes induces downregulation of Thl characteristics and a transition of a Th2-like phenotype. J Exp Med 1994; 179: 481.
    • (1994) J Exp Med , vol.179 , pp. 481
    • Gajewski, T.F.1    Lancki, D.W.2    Stack, R.3    Fitch, F.W.4
  • 59
    • 0026316280 scopus 로고
    • Clonal anergy blocks the response to IL-4 as well as the production of IL-2 in dual-producing T helper cell clones
    • Mueller DL, Chiodetti L, Bacon PA, Schwartz RH. Clonal anergy blocks the response to IL-4 as well as the production of IL-2 in dual-producing T helper cell clones. J Immunol 1991; 147: 4118.
    • (1991) J Immunol , vol.147 , pp. 4118
    • Mueller, D.L.1    Chiodetti, L.2    Bacon, P.A.3    Schwartz, R.H.4
  • 60
    • 0028339765 scopus 로고
    • Antigen-specific activation, tolerization, and reactivation of the interleukin 4 pathway in vivo
    • Rocken M, Urban J, Shevach EM. Antigen-specific activation, tolerization, and reactivation of the interleukin 4 pathway in vivo. J Exp Med 1994; 179: 1885.
    • (1994) J Exp Med , vol.179 , pp. 1885
    • Rocken, M.1    Urban, J.2    Shevach, E.M.3
  • 62
    • 0028361047 scopus 로고
    • Role of cytokines in determining T-lymphocyte function
    • O’Garra A, Murphy K. Role of cytokines in determining T-lymphocyte function. Curr Opin Immunol 1994; 6: 458.
    • (1994) Curr Opin Immunol , vol.6 , pp. 458
    • O’Garra, A.1    Murphy, K.2
  • 63
    • 0028178135 scopus 로고
    • Adoptive transfer of a Th2-like cell line prolongs MHC class II antigen disparate skin allograft survival in the mouse
    • Maeda H, Takata M, Takahashi S, Ogoshi S, Fujimoto S. Adoptive transfer of a Th2-like cell line prolongs MHC class II antigen disparate skin allograft survival in the mouse. Int Immunol 1994; 6: 855.
    • (1994) Int Immunol , vol.6 , pp. 855
    • Maeda, H.1    Takata, M.2    Takahashi, S.3    Ogoshi, S.4    Fujimoto, S.5
  • 64
    • 0026087469 scopus 로고
    • Kidney allograft tolerance in primates without chronic immunosuppression-the role of veto cells
    • Thomas JM, Carver FM, Cunningham PR, Olson LC, Thomas FT. Kidney allograft tolerance in primates without chronic immunosuppression-the role of veto cells. Transplantation 1991; 51: 198.
    • (1991) Transplantation , vol.51 , pp. 198
    • Thomas, J.M.1    Carver, F.M.2    Cunningham, P.R.3    Olson, L.C.4    Thomas, F.T.5
  • 65
    • 0028308645 scopus 로고
    • + T cells: Their activation and effector functions
    • + T cells: their activation and effector functions. Curr Opin Immunol 1994; 6: 453.
    • (1994) Curr Opin Immunol , vol.6 , pp. 453
    • Le Gros, G.1    Erard, F.2
  • 66
    • 0026682860 scopus 로고
    • Mechanism of protection from graft-versus-host disease mortality by IL-2. III. Early reductions in donor T cell subsets and expansion of a CD3+CD4- CD8- cell population
    • Abraham VS, Sachs DH, Sykes M. Mechanism of protection from graft-versus-host disease mortality by IL-2. III. Early reductions in donor T cell subsets and expansion of a CD3+CD4- CD8- cell population. J Immunol 1992; 148: 3746.
    • (1992) J Immunol , vol.148 , pp. 3746
    • Abraham, V.S.1    Sachs, D.H.2    Sykes, M.3
  • 67
    • 0028202792 scopus 로고
    • Oral tolerance: Immunologic mechanisms and treatment of animal and human or- gan-specific autoimmune diseases by oral administration of autoantigens
    • Weiner HL, Friedman A, Miller A, et al. Oral tolerance: immunologic mechanisms and treatment of animal and human or- gan-specific autoimmune diseases by oral administration of autoantigens. Annu Rev Immunol 1994; 12: 809.
    • (1994) Annu Rev Immunol , vol.12 , pp. 809
    • Weiner, H.L.1    Friedman, A.2    Miller, A.3
  • 68
    • 0027153195 scopus 로고
    • Unmodified pancreatic islet allograft rejection results in the preferential expression of certain T cell activation transcripts
    • O’Connell P, Pacheco-Silva A, Nickerson P, et al. Unmodified pancreatic islet allograft rejection results in the preferential expression of certain T cell activation transcripts. J Immunol 1993; 150: 1093.
    • (1993) J Immunol , vol.150 , pp. 1093
    • O’Connell, P.1    Pacheco-Silva, A.2    Nickerson, P.3
  • 69
    • 0025784062 scopus 로고
    • Cytokine gene transcription in vascularised organ grafts: Analysis using semiquantitative polymerase chain reaction
    • Dallman MJ, Larsen CP, Morris PJ. Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction. J Exp Med 1991; 174: 493.
    • (1991) J Exp Med , vol.174 , pp. 493
    • Dallman, M.J.1    Larsen, C.P.2    Morris, P.J.3
  • 70
    • 0028842198 scopus 로고
    • Cytokine mRNA profiles in mouse orthotopic liver transplantation: Graft rejection is associated with augmented Th1 function
    • Thai NL, Fu F, Qian S, et al. Cytokine mRNA profiles in mouse orthotopic liver transplantation: graft rejection is associated with augmented Th1 function. Transplantation 1995; 59: 274.
    • (1995) Transplantation , vol.59 , pp. 274
    • Thai, N.L.1    Fu, F.2    Qian, S.3
  • 71
    • 0026542681 scopus 로고
    • Cytokine and T cell receptor gene expression at the site of allograft rejection
    • Krams SM, Falco DA, Villanueva JC, et al. Cytokine and T cell receptor gene expression at the site of allograft rejection. Transplantation 1992; 53: 151.
    • (1992) Transplantation , vol.53 , pp. 151
    • Krams, S.M.1    Falco, D.A.2    Villanueva, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.