Of mice and mutants: target size and sensitivity

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 331, Issue 2, 1995, Pages 225-228

  Skopek, Thomas R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

GENE TARGETING; MOUSE; MUTANT; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; TRANSGENIC MOUSE;

ALKYLATING AGENTS; ANIMAL; BACTERIAL PROTEINS; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MICE; MICE, TRANSGENIC; MUTAGENESIS; MUTAGENICITY TESTS; REPRESSOR PROTEINS; SENSITIVITY AND SPECIFICITY; TRANSGENES;

EID: 0028786356     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/0027-5107(95)00070-Y     Document Type: Article

References (7)

1. Toxicity, mutagenicity and mutational spectra of N-ethyl-N-nitrosurea in human cell lines with different DNA repair phenotypes
2. Influence of neighboring base sequence on the distribution and repair of N-ethyl-N-nitrosurea-induced lesions in Escherichia coli
3. Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo
4. Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice
5. Characterization of mutations induced by ethylnitrosurea in seminiferous germ cells of transgenic B6C3F1 mice
6. TM B6C3F1 mice
7. Geneomic DNA sequencing of mRNA splicing mutants in the hprt gene of Chinese hamster ovary cells