Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle: Implications for glucose toxicity

Journal of Clinical Investigation

Volumn 96, Issue 6, 1995, Pages 2792-2801

  Baron, Alain D ^a   Zhu, Jin Su ^a   Zhu, Ju Hong ^b   Weldon, Heather ^a   Maianu, Lidia ^b   Garvey, W Timothy ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Euglycemic clamp; Glucose transporter; GLUT 4; Hexosamine; Insulin resistance

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); GALACTOSAMINE; GLUCOSAMINE; GLUCOSE; GLUCOSE TRANSPORTER; HEXOSAMINE; INSULIN; MANNOSAMINE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MEMBRANE TRANSPORT; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOLEMMA; SKELETAL MUSCLE;

ANIMAL; BLOOD GLUCOSE; CELL MEMBRANE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSAMINE; GLUCOSE; GLUCOSE CLAMP TECHNIQUE; HYPERINSULINISM; INFUSIONS, INTRAVENOUS; INSULIN; INSULIN RESISTANCE; KINETICS; MALE; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0028784442     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118349     Document Type: Article

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