Regulation of cholesterol synthesis in four colonic adenocarcinoma cell lines

Lipids

Volumn 30, Issue 12, 1995, Pages 1083-1092

  Cerda, Sonia R ^a,b   Wilkinson, John ^a,b   Broitman, Selwyn A ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYCHOLESTEROL; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MEVINOLIN;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CHOLESTEROL SYNTHESIS; COLON ADENOCARCINOMA; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; INTESTINE CELL;

ADENOCARCINOMA; BINDING, COMPETITIVE; BLOOD; CHOLESTEROL; COLONIC NEOPLASMS; CULTURE MEDIA; ENZYME INHIBITORS; HUMAN; HYDROXYCHOLESTEROLS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPOPROTEINS, LDL; LIPOPROTEINS, LDL CHOLESTEROL; LOVASTATIN; RECEPTORS, LDL; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED;

BOVINAE;

EID: 0028784203     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/BF02536608     Document Type: Article

References (65)

1. Role of Cholesterol Metabolism in Cell Growth
2. A Receptor-Mediated Pathway for Cholesterol Homeostasis
3. Loss of Feedback Control of Hydroxymethylglutaryl Coenzyme A Reductase in Hepatomas
4. Regulation of Sterol Synthesis in Leukaemic Blast Cells: A Defect Resembling Familial Hypercholesterolaemia
5. Renal Cell Carcinoma in the Wistar-Lewis rat: A Model for Studying the Mechanisms of Cholesterol Acquisition by a Tumor in vivo
6. Elevated Uptake of Low Density Lipoproteins by Human Lung Cancer Tissue in vivo
7. In vivo Assimilation of Low Density Lipoproteins by a Fibrosarcoma Tumour Line in Mice
8. Low-Density Lipoprotein Metabolism in Mice with Soft Tissue Tumours
9. Assimilation of LDL by Experimental Tumours in Mice
10. Low-Density Lipoprotein (LDL) Receptor Activity in Human Acute Myelogenous Leukemia Cells
11. Cholesterol Metabolism in Cancer Cells in Monolayer Culture III. Low-Density Lipoprotein Metabolism
12. Elevated Low Density Lipoprotein Receptor Activity in Leukemic Cells with Monocytic Differentiation
13. Hypocholesterolaemia in Malignancy Due to Elevated Low-Density-Lipoprotein-Receptor Activity in Tumour Cells: Evidence from Studies in Patients with Leukaemia
14. Low Density Lipoprotein Receptor Activity in Human Intracranial Tumors and Its Relation to the Cholesterol Requirement
15. Regulation of HMG-CoA reductase
16. Regulation of the Mevalonate Pathway
17. Evidence for Post-Translational Incorporation of a Product of Mevalonic Acid into Swiss 3T3 Cell Proteins
18. Post-Translational Modification of Proteins by Isoprenoids in Mammalian Cells
19. 3-Hydroxyl-3-Methylglutaryl Coenzyme A Reductase in Human Brain Tumors
20. Expression of the 3-Hydroxy-3-Methylglutaryl Coenzyme A-Reductase and LDL-Receptor and LDL-Receptor Genes in Human Embryonic Tumours and in Normal Foetal Tissues
21. Importance of Mevalonate-Derived Products in the Control of HMG-CoA Reductase Activity and Growth of Human Lung Adenocarcinoma Cell Line A549
22. The Low-Density Lipoprotein Patyway and Its Relation to Attherosclerosis
23. The Discovery and Development of HMG-CoA Reductase Inhibitors
24. Inhibition of Cholesterol Synthesis with Compactin Renders Growth of Cultured Cells Dependent on the Low Density Lipoprotein Receptor
25. Evidence for Deficiency of Low Density Lipoprotein Receptor on Human Colonic Carcinoma Cell Lines
26. Compartmentalization of Cholesterol Metabolism and Cellular Growth in Cultured Intestinal Crypt Cells
27. Mevinolin, A Competitive Inhibitor of Hydroxymethylglutaryl Coenzyme A Reductase, Suppresses Enterolcyte Esterification of Exogenous. But Not Endogenous Cholesterol
28. Regulation of Cholesterol Metabolism and Low-Density Lipoprotein Binding in Human Intestinal Caco-2 Cells
29. Fate of Exogensous and Newly Synthesized Cholesterol in Intestinal Cell Lines
30. Epithelial Polarity, Villin Expression and Enterocytic Differentiation of Cultured Human Colon Carcinoma Cells: A Survey of Twenty Cell Lines
31. Induction of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts Incubated with Compactin (ML-236B), A Competitive Inhibitor of the Reductase
32. Receptor-Mediated Endocytosis of Low-Density Lipoprotein in Cultured Cells
33. Cholesterol Ester Formation in Cultured Human Fiborblasts. Stimulation by Oxygenated Sterols
34. Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts. Comparison of Cells from A Normal Subject and from a Patient with Homozygous Familial Hypercholesterolemia
35. Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Human Fibroblasts by Lipoproteins
36. Cholesterol Synthesis and Low Density Lipoprotein Uptake Are Regulated Independently in Rat Small Intestinal Epithelium
37. Cholesterol Uptake in the Human Intestine. Hypo- and Hyperresponsivenuess
38. Role of Acyl-CoA: Cholesterol Acyltransferase in Cellular Cholesterol Metabolism
39. Metabolism of Low-Density Lipoprotein in Differentiated and Undifferentiated HT29 Colon Cancer Cells
40. Regulation of Cholesterol Synthesis and Binding of Lipoproteins in Cultured Rat Intestinal Epithelial Cells
41. Acyl-CoA: Cholesterol Acyltransferase in HT 29 Cell Subpopulations. Defect of Activity in the Undifferentiated Cells
42. Dietary Cholesterol, Serum Cholesterol, and Colon Cancer: A Review
43. Declining Serum Cholesterol Levels Prior to Diagnosis of Colon Cancer. A Time-Trend, Case-Control Study
44. Cancer Mortality and Lipid and Lipoprotein Levels. Lipid Research Clinics Program Mortality Follow-up Study
45. Serum Cholesterol Level, Body Mass Index, and the Risk of Colon Cancer. The Framingham Study
46. Immunohistochemical Localization of Low Density Lipoprotein Receptors in Adrenal Gland, Liver, and Intestine
47. Relation of Growth- and Sterol-Related Regulatory Pathways for Low Density Lipoprotein Receptor Gene Expression
48. The Regulation of Hydroxymethylglutaryl-CoA Reductase in Cultured Cells
49. Demonstration of Low Density Lipoprotein Receptor in Human Colonic Carcinoma and Surrounding Mucosa by Immunoenzymatic Assay
50. Absolute Rates of Cholesterol Synthesis in Rat Intestine in vitro and in vivo: A Comparison of Different Substrates in Slices and Isolated Cells
51. Role of Contact Inhibition in the Regulation of Receptor-Mediated Uptake of Low Density Lipoprotein in Cultured Vascular Endothelial Cells
52. Effect of Cell Density on Binding and Uptake of Low Density Lipoprotein by Human Fibroblasts
53. Effect of Cell Density and Confluency on Cholesterol Metabolism in Cancer Cells in Monolayer Culture
54. Effects of Low- and High-Density Lipoproteins on the Proliferation of Human Breast Cancer Cells in vitro: Differeces Between Hormone-Dependent and Hormone-Independent Cell Lines
55. Metabolism of Low- Density Lipoprotein in Differentiated and Uniifferentiated Ht 29 Colon Cancer Cells
56. Regulation of Low-Density Lipoprotein Metabolism by Cell Density and Proliferative State
57. Ras Oncogene p21 Levels Parallel Malignant Potential of Different Human Colonic Benign Conditions
58. Monoclonal Antibodies of Predefined Specificity Detect Activated ras Gene Expression in Human Mammary Carcinomas
59. Importance of Mevalonate-Derived Products in the Control of HMG-CoA Reductase Activity and Growth of Human Lung Adenocarcinoma Cell Line A549
60. Suppression of Murine Neuroblastoma Growth in vivo by Mevinolin, A Competitive Inhibitor of 3-Hydroxy-3-Methylglutary-Coenzyme A Reductase
61. Inhibition of Pancreatic Adencarcinoma Cell Growth by Lovastatin