Role of the syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

Journal of Experimental Medicine

Volumn 182, Issue 6, 1995, Pages 1815-1823

  Kurosaki, Tomohiro ^a,b   Johnson, Sara A ^c   Pao, Lily ^c,d   Sada, Kiyonao ^e   Yamamura, Hirohei ^e   Cambier, John C ^c,d  

^a WYETH RESEARCH   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CALCIUM TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; B-LYMPHOCYTES; CALCIUM; CELLS, CULTURED; ENZYME PRECURSORS; INOSITOL 1,4,5-TRISPHOSPHATE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASE; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028783396     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.182.6.1815     Document Type: Article

References (43)

1. Reth, M. 1992. Antigen receptors on B lymphocytes. Annu. Rev. Immunol. 10: 97-121.
2. Pleiman, C.M., D. D’Ambrosio, and J.C. Cambier. 1994. The B-cell antigen receptor complex: structure and signal transduction. Immunol. Today. 15: 393-398.
3. Cambier, J.C. 1995. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunol. Today. 16:110.
4. Reth, M. 1989. Antigen receptor tail clue. Nature (Lond.). 338: 383-384.
5. Samelson, L.E., and R.D. Klausner. 1992. Tyrosine kinases and tyrosine-based activation motifs: current research on activation via the T cell antigen receptor. J. Biol. Chem. 267: 24913-24916.
6. Weiss, A., and D.R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell. 76: 263-274.
7. Burkhardt, A.L., M. Brunswick, J.B. Bolen, andJ.J. Mond. 1991. Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases. Proc. Natl. Acad. Sci. USA. 88: 7410-7414.
8. Campbell, M.-A., and B.M. Sefton. 1992. Association between B-lymphocyte membrane immunoglobulin and multiple members of the src family of protein tyrosine kinases. Mol. Cell. Biol. 12: 2315-2321.
9. Yamanashi, Y., T. Kakiuchi, J. Mizuguchi, T. Yamamoto, and K. Toyoshima. 1991. Association ofB cell antigen receptor with protein tyrosine kinase Lyn. Science (Wash. DC). 251:192-194.
10. Hutchcroft, J.E., M.L. Harrison, and R.L. Geahlen. 1992. Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor. J. Biol. Chem. 267: 8613-8619.
11. Yamada, T., T. Taniguchi, C. Yang, S. Yasue, H. Saito, and H. Yamamura. 1993. Association with B-cell antigen receptor with protein-tyrosine kinase p72syk and activation by engagement of membrane IgM. Eur.J. Biochem. 213: 455-459.
12. Taniguchi, T., T. Kobayashi, J. Kondo, K. Takahashi, H. Nakamura, J. Suzuki, K. Nagai, T. Yamada, S. Nakamura, and H. Yamamura. 1991. Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis. J. Biol. Chem. 266: 15790-15796.
13. Gold, M.R., D.A. Law, and A.L. DeFranco. 1990. Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor. Nature (Lond.). 345: 810-813.
14. Campbell, M.-A., and B.M. Sefton. 1990. Protein tyrosine phosphorylation is induced in murine B lymphocytes in response to stimulation with anti-immunoglobulin. EMBO (Eur. Mol. Biol. Organ.) J. 9: 2125-2131.
15. Gold, M.R., L. Matsuuchi, R.B. Kelly, and A.L. DeFranco. 1991. Tyrosine phosphorylation of components of the B-cell antigen receptor following receptor crosslinking. Proc. Natl. Acad. Sci. USA. 88: 3436-3440.
16. Coggeshall, K.M., J.C. McHugh, and A. Altman. 1992. Predominant expression and activation-induced tyrosine phosphorylation of phospholipase C-y2 in B lymphocytes. Proc. Natl. Acad. Sci. USA. 89: 5660-5664.
17. Flaswinkel, H., and M. Reth. 1994. Dual role of the tyrosine activation motif of the Ig-0£ protein during signal transduction via the B cell antigen receptor. EMBO (Eur. Mol. Biol. Organ.) J. 13: 83-89.
18. Sanchez, M., Z. Misulovin, A.L. Burkhardt, S. Mahajan, T. Costa, R. Franke, J.B. Bolen, and M. Nussenzweig. 1993. Signal transduction by immunoglobulin is mediated through Ig-a and Ig-PJ. Exp. Med. 178: 1049-1057.
19. Clark, M.R., S.A. Johnson, and J.C. Cambier. 1994. Signal propagation by ARH-1 motif containing receptors: tyrosine phosphorylation of Ig-a enhances binding and activation of fyn. EMBO (Eur. Mol. Biol. Organ.) J. 13: 1911-1919.
20. Pleiman, C.M., F. Abrams, L. Timson-Gauen, W. Bedzyk, J. Jongstra, A.S. Shaw, and J.C. Cambier. 1994. Distinct p53/ 56lyn domains associate with nonphosphorylated and phosphorylated Ig-a. Proc. Natl. Acad. Sci. USA. 91: 4268-4272.
21. Nishibe, S., M.L Wahl, S.M. Hemandez-Sotomayor, N.K. Tonks, S.G. Rhee, and G. Carpenter. 1990. Increase of the catalytic activity of phospholipase C-yl by tyrosine phosphorylation. Science (Wash. DC). 250: 1253-1256.
22. Takata, M., H. Sabe, A. Hata, T. Inazu, Y. Homma, T. Nukada, H. Yamamura, and T. Kurosaki. 1994. Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways. EMBO (Eur. Mol. Biol. Organ.) J. 13: 1341-1349.
23. Reth, M., E. Petrac, P. Wiese, L. Lobel, and F.W. Alt. 1987. Activation of V gene rearrangements in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains. EMBO (Eur. Mol. Biol. Organ.)J. 6: 3299-3305.
24. Chen, C.-L.H., J.E. Lehmeyer, and M.D. Cooper. 1982. Evidence for an IgD homologue on chicken lymphocytes. J. Immunol. 129: 2580-2585.
25. Homma, Y., Y. Emori, F. Shibasaki, K. Suzuki, and T. Takenawa. 1990. Isolation and characterization of a y-type phos-phoinositide-specific phospholipase C (PLC-y2). Biochem. J. 269: 13-18.
26. ++ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450.
27. Chan, A., M. Iwashima, C. Turck, and A. Weiss. 1992. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR£ chain. Cell. 71: 649-662.
28. Iwashima, M., B. Irving, N. van Oers, A. Chan, and A. Weiss. 1994. Sequential interaction of the TCR with two distinct cytoplasmic tyrosine kinases. Science (Wash. DC). 263: 1136-1139.
29. Friedrich, R.J., K.S. Campbell, and J.C. Cambier. 1993. The gamma subunit of the B cell antigen receptor complex is a C-terminally tmncated product of the B29 gene. J. Immunol. 150: 2814-2822.
30. Kurosaki, T., M. Takata, Y. Yamanashi, T. Inazu, T. Taniguchi, T. Yamamoto, and H. Yamamura. 1994. Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling. J. Exp. Med. 179: 1725-1729.
31. Caron, L., N. Abraham, T. Pawson, and A. Veillette. 1992. Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck. Mol. Cell. Biol. 12: 2720-2729.
32. Hanks, S.K., and A.M. Quinn. 1991. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. In Methods in Enzymology. T. Hunter and B.M. Sefton, editors. Academic Press, Inc., San Diego, CA. 38-62.
33. Koch, C.A., D. Anderson, M.F. Moran, C. Ellis, and T. Pawson. 1991. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science (Wash. DC). 252: 668-674.
34. Pawson, T., and G.D. Gish. 1992. SH2 and SH3 domains: from structure to function. Cell. 71: 359-362.
35. syk with the γ and β subunits of the high-affinity receptor immunoglobulin E, FceRI. Mol. Cell. Biol. 15: 272-281.
36. Kim, K.M., G. Alber, P. Weiser, and M. Reth. 1993. Differential signaling through the Ig-a and Ig-(3 components of the B cell antigen receptor. Eur.J. Immunol. 23: 911-916.
37. Shiue, L., M.J. Zoller, andJ.S. Brugge. 1995. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem. 270: 10498-10592.
38. Rowley, R.B., A.L. Burkhardt, H.-G. Chao, G.R. Matsueda, and J.B. Bolen. 1995. Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Iga/Igfl imrnunoreceptor tyrosine activation motif binding and autophosphorylation.J. Biol. Chem. 270: 11590-11594.
39. Kolanus, W., C. Romeo, and B. Seed. 1993. T cell activation by clustered tyrosine kinases. Cell. 74: 171-183.
40. Clark, M.R., K.S. Campbell, A. Kazlauskas, S.A. Johnson, M. Hertz, T.A. Potter, C. Pleiman, andJ.C. Cambier. 1992. The B cell antigen receptor complex: association of Ig-a and Ig-(3 with distinct cytoplasmic effectors. Science (Wash. DC). 258: 123-126.
41. Pleiman, C.M., M.R. Clark, L.K. Timson-Gauen, S. Winitz, K.M. Coggeshall, G.L. Johnson, A.S. Shaw, and J.C. Cambier. 1993. Mapping of sites on the Src family protein tyrosine kinases p55w\ p597", and p56(t" which interact with the effector molecules phospholipase C-y2, microtubuleassociated protein kinase, GTPase-activating protein, and phosphatidylinositol 3-kinase. Mol. Cell. Biol. 13: 5877-5887.
42. Saouaf, S.J., S. Mahajan, R.B. Rowley, S.A. Kut, J. Fargnoli, A.L. Burkhardt, S. Tsukada, O.N. Witte, andJ.B. Bolen. 1994. Temporal differences in the activation of three classes of nontransmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc. Natl. Acad. Sci. USA. 91: 9524-9528.
43. Law, D.A., V.W.F. Chan, S.K. Datta, and A.L. DeFranco. 1993. B-cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn. Current Biology. 3: 654-657.