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Volumn 330, Issue 9, 1994, Pages 613-622

Excitatory amino acids as a final common pathway for neurologic disorders

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; ALLOPURINOL; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; APTIGANEL; CALCIUM; CALCIUM CHANNEL; DANTROLENE; DEXTROMETHORPHAN; DEXTRORPHAN; DIZOCILPINE; EXCITATORY AMINO ACID RECEPTOR; FELBAMATE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; GLYCERYL TRINITRATE; IFENPRODIL; KAINIC ACID; KAINIC ACID RECEPTOR; KETAMINE; LIFARIZINE; MAGNESIUM; MEMANTINE; MONOSIALOGANGLIOSIDE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTOXIN; NIMODIPINE; PHENCYCLIDINE; PHENYTOIN; REMACEMIDE; RILUZOLE; TIRILAZAD; UNINDEXED DRUG; GLUTAMIC ACID DERIVATIVE; N METHYLASPARTIC ACID;

EID: 0028762647     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199403033300907     Document Type: Review
Times cited : (2560)

References (89)
  • 1
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi DW Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988; 1: 623-634
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 2
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum B, Garthwaite J Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol Sci 1990; 11: 379-387
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 3
    • 0026569410 scopus 로고
    • Models of neuronal injury in AIDS: another role for the NMDA receptor?
    • Lipton SA Models of neuronal injury in AIDS: another role for the NMDA receptor? Trends Neurosci 1992; 15: 75-79
    • (1992) Trends Neurosci , vol.15 , pp. 75-79
    • Lipton, S.A.1
  • 4
    • 0026596478 scopus 로고
    • Molecular neurobiology of glutamate receptors
    • Gasic GP, Hollmann M Molecular neurobiology of glutamate receptors. Annu Rev Physiol 1992; 54: 507-536
    • (1992) Annu Rev Physiol , vol.54 , pp. 507-536
    • Gasic, G.P.1    Hollmann, M.2
  • 5
    • 0024392837 scopus 로고
    • Neurotransmitter regulation of neuronal outgrowth, plasticity and survival
    • Lipton SA, Kater SB Neurotransmitter regulation of neuronal outgrowth, plasticity and survival. Trends Neurosci 1989; 12: 265-270
    • (1989) Trends Neurosci , vol.12 , pp. 265-270
    • Lipton, S.A.1    Kater, S.B.2
  • 6
    • 0001933595 scopus 로고
    • Neurotoxicity of excitatory amino acids
    • McGeer EG, Olney JW, McGeer PL, eds., New York: Raven Press
    • Olney JW. Neurotoxicity of excitatory amino acids. In: McGeer EG, Olney JW, McGeer PL, eds. Kainic acid as a tool in neurobiology. New York: Raven Press, 1978:95-121.
    • (1978) Kainic acid as a tool in neurobiology , pp. 95
    • Olney, J.W.1
  • 7
    • 0021961417 scopus 로고
    • Glutamate neurotoxicity in cortical cell culture is calcium dependent
    • Choi DW Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci Lett 1985; 58: 293-297
    • (1985) Neurosci Lett , vol.58 , pp. 293-297
    • Choi, D.W.1
  • 8
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications for brain function
    • Nakanishi S Molecular diversity of glutamate receptors and implications for brain function. Science 1992; 258: 597-603
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 9
    • 0027404879 scopus 로고
    • GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses
    • Donevan SD, Rogawski MA GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses. Neuron 1993; 10: 51-59
    • (1993) Neuron , vol.10 , pp. 51-59
    • Donevan, S.D.1    Rogawski, M.A.2
  • 10
    • 0027464959 scopus 로고
    • A benzodiazepine recognition site associated with the non-NMDA glutamate receptor
    • Zorumski CF, Yamada KA, Price MT, Olney JW A benzodiazepine recognition site associated with the non-NMDA glutamate receptor. Neuron 1993; 10: 61-67
    • (1993) Neuron , vol.10 , pp. 61-67
    • Zorumski, C.F.1    Yamada, K.A.2    Price, M.T.3    Olney, J.W.4
  • 11
    • 0022479032 scopus 로고
    • NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
    • [Erratum, Nature 1986;321:888.]
    • MacDermott AB, Mayer ML, Westbrook GL, Smith SJ, Barker JL NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 1986; 321: 519-522 [Erratum, Nature 1986;321:888.]
    • (1986) Nature , vol.321 , pp. 519-522
    • MacDermott, A.B.1    Mayer, M.L.2    Westbrook, G.L.3    Smith, S.J.4    Barker, J.L.5
  • 12
    • 0025923461 scopus 로고
    • Ca2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition
    • Hollmann M, Hartley M, Heinemann S Ca2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition. Science 1991; 252: 851-853
    • (1991) Science , vol.252 , pp. 851-853
    • Hollmann, M.1    Hartley, M.2    Heinemann, S.3
  • 13
    • 0025806264 scopus 로고
    • Calcium channel antagonists attenuate NMDA receptor-mediated neurotoxicity of retinal ganglion cells in culture
    • [Erratum, Brain Res 1991;559:179.]
    • Sucher NJ, Lei SZ, Lipton SA Calcium channel antagonists attenuate NMDA receptor-mediated neurotoxicity of retinal ganglion cells in culture. Brain Res 1991; 551: 297-302 [Erratum, Brain Res 1991;559:179.]
    • (1991) Brain Res , vol.551 , pp. 297-302
    • Sucher, N.J.1    Lei, S.Z.2    Lipton, S.A.3
  • 14
    • 0024554076 scopus 로고
    • Classes of calcium channels in vertebrate cells
    • Bean BP Classes of calcium channels in vertebrate cells. Annu Rev Physiol 1989; 51: 367-384
    • (1989) Annu Rev Physiol , vol.51 , pp. 367-384
    • Bean, B.P.1
  • 15
    • 0026264722 scopus 로고
    • Calcium channel antagonists in the prevention of neurotoxicity
    • Lipton SA Calcium channel antagonists in the prevention of neurotoxicity. Adv Pharmacol 1991; 22: 271-297
    • (1991) Adv Pharmacol , vol.22 , pp. 271-297
    • Lipton, S.A.1
  • 16
    • 0027074763 scopus 로고
    • Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity
    • Lei SZ, Zhang D, Abele AE, Lipton SA Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity. Brain Res 1992; 598: 196-202
    • (1992) Brain Res , vol.598 , pp. 196-202
    • Lei, S.Z.1    Zhang, D.2    Abele, A.E.3    Lipton, S.A.4
  • 17
    • 0026572466 scopus 로고
    • Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons
    • Frandsen A, Schousboe A Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc Natl Acad Sci U S A 1992; 89: 2590-2594
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 2590-2594
    • Frandsen, A.1    Schousboe, A.2
  • 18
    • 0025943535 scopus 로고
    • Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats
    • Buchan AM, Li H, Cho S, Pulsinelli WA Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. Neurosci Lett 1991; 132: 255-258
    • (1991) Neurosci Lett , vol.132 , pp. 255-258
    • Buchan, A.M.1    Li, H.2    Cho, S.3    Pulsinelli, W.A.4
  • 19
    • 0026623418 scopus 로고
    • Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat
    • Smith SE, Meldrum BS Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat. Stroke 1992; 23: 861-864
    • (1992) Stroke , vol.23 , pp. 861-864
    • Smith, S.E.1    Meldrum, B.S.2
  • 20
    • 0026093663 scopus 로고
    • Intracellular calcium concentrations during “chemical hypoxia” and excitotoxic neuronal injury
    • Dubinsky JM, Rothman SM Intracellular calcium concentrations during “chemical hypoxia” and excitotoxic neuronal injury. J Neurosci 1991; 11: 2545-2551
    • (1991) J Neurosci , vol.11 , pp. 2545-2551
    • Dubinsky, J.M.1    Rothman, S.M.2
  • 21
    • 0027215902 scopus 로고
    • Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways
    • Bading H, Ginty DD, Greenberg ME Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 1993; 260: 181-186
    • (1993) Science , vol.260 , pp. 181-186
    • Bading, H.1    Ginty, D.D.2    Greenberg, M.E.3
  • 22
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski M, Charlton MP, Carlen PL, Tator CH Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci 1993; 13: 2085-2104
    • (1993) J Neurosci , vol.13 , pp. 2085-2104
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 23
    • 0024467943 scopus 로고
    • A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity
    • Mattson MP, Guthrie PB, Kater SB A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity. FASEB J 1989; 3: 2519-2526
    • (1989) FASEB J , vol.3 , pp. 2519-2526
    • Mattson, M.P.1    Guthrie, P.B.2    Kater, S.B.3
  • 24
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall RD, Thayer SA Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J Neurosci 1992; 12: 1882-1895
    • (1992) J Neurosci , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 25
    • 0026760948 scopus 로고
    • A novel neuronal messenger molecule in brain: the free radical, nitric oxide
    • Dawson TM, Dawson VL, Snyder SH A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann Neurol 1992; 32: 297-311
    • (1992) Ann Neurol , vol.32 , pp. 297-311
    • Dawson, T.M.1    Dawson, V.L.2    Snyder, S.H.3
  • 26
    • 0027441572 scopus 로고
    • N-Methyl-D-aspartate receptor excitotoxicity involves activation of polyamine synthesis: protection by α-difluoromethylornithine
    • Trout JJ, Koenig H, Goldstone AD, Iqbal Z, Lu CY, Siddiqui F N-Methyl-D-aspartate receptor excitotoxicity involves activation of polyamine synthesis: protection by α-difluoromethylornithine. J Neurochem 1993; 60: 352-355
    • (1993) J Neurochem , vol.60 , pp. 352-355
    • Trout, J.J.1    Koenig, H.2    Goldstone, A.D.3    Iqbal, Z.4    Lu, C.Y.5    Siddiqui, F.6
  • 27
    • 0027081205 scopus 로고
    • Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor
    • Clark GD, Happel LT, Zorumski CF, Bazan NG Enhancement of hippocampal excitatory synaptic transmission by platelet-activating factor. Neuron 1992; 9: 1211-1216
    • (1992) Neuron , vol.9 , pp. 1211-1216
    • Clark, G.D.1    Happel, L.T.2    Zorumski, C.F.3    Bazan, N.G.4
  • 28
    • 0026788571 scopus 로고
    • Platelet-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons
    • Bito H, Nakamura M, Honda Z, Platelet-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons. Neuron 1992; 9: 285-294
    • (1992) Neuron , vol.9 , pp. 285-294
    • Bito, H.1    Nakamura, M.2    Honda, Z.3
  • 29
    • 0026570085 scopus 로고
    • Potentiation of NMDA receptor currents by arachidonic acid
    • Miller B, Sarantis M, Traynelis SF, Attwell D Potentiation of NMDA receptor currents by arachidonic acid. Nature 1992; 355: 722-725
    • (1992) Nature , vol.355 , pp. 722-725
    • Miller, B.1    Sarantis, M.2    Traynelis, S.F.3    Attwell, D.4
  • 30
    • 0026634153 scopus 로고
    • High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes
    • Volterra A, Trotti D, Cassutti P, High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes. J Neurochem 1992; 59: 600-606
    • (1992) J Neurochem , vol.59 , pp. 600-606
    • Volterra, A.1    Trotti, D.2    Cassutti, P.3
  • 31
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal M, Pietri S, Culcasi M, Bockaert J NMDA-dependent superoxide production and neurotoxicity. Nature 1993; 364: 535-537
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 33
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen DR, Siddique T, Patterson D, Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 1993; 362: 59-62
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 34
    • 0027194540 scopus 로고
    • A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
    • Lipton SA, Choi Y-B, Pan Z-H, A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993; 364: 626-632
    • (1993) Nature , vol.364 , pp. 626-632
    • Lipton, S.A.1    Choi, Y.-B.2    Pan, Z.-H.3
  • 37
    • 0027717968 scopus 로고
    • Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species
    • Kane DJ, Sarafian TA, Anton R, Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 1993; 262: 1274-1277
    • (1993) Science , vol.262 , pp. 1274-1277
    • Kane, D.J.1    Sarafian, T.A.2    Anton, R.3
  • 39
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi DW Ionic dependence of glutamate neurotoxicity. J Neurosci 1987; 7: 369-379
    • (1987) J Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 40
    • 0021828430 scopus 로고
    • Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo
    • Kvamme E, Schousboe A, Hertz L, Torgner IA, Svenneby G Developmental change of endogenous glutamate and gamma-glutamyl transferase in cultured cerebral cortical interneurons and cerebellar granule cells, and in mouse cerebral cortex and cerebellum in vivo. Neurochem Res 1985; 10: 993-1008
    • (1985) Neurochem Res , vol.10 , pp. 993-1008
    • Kvamme, E.1    Schousboe, A.2    Hertz, L.3    Torgner, I.A.4    Svenneby, G.5
  • 41
    • 0026463206 scopus 로고
    • The glial cell glutamate uptake carrier countertransports pH-changing anions
    • Bouvier M, Szatkowski M, Amato A, Attwell D The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 1992; 360: 471-474
    • (1992) Nature , vol.360 , pp. 471-474
    • Bouvier, M.1    Szatkowski, M.2    Amato, A.3    Attwell, D.4
  • 42
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H, Drejer J, Schousboe A, Diemer NH Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984; 43: 1369-1374
    • (1984) J Neurochem , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 43
    • 0026596688 scopus 로고
    • Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture
    • Rosenberg PA, Amin S, Leitner M Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture. J Neurosci 1992; 12: 56-61
    • (1992) J Neurosci , vol.12 , pp. 56-61
    • Rosenberg, P.A.1    Amin, S.2    Leitner, M.3
  • 44
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na+-dependent glutamate/aspartate transporter from rat brain
    • Storck T, Schulte S, Hofmann K, Stoffel W Structure, expression, and functional analysis of a Na+-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci U S A 1992; 89: 10955-10959
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 45
    • 0026486310 scopus 로고
    • Cloning and expression of a rat brain L-glutamate transporter
    • Pines G, Danbolt NC, Bjoras M, Cloning and expression of a rat brain L-glutamate transporter. Nature 1992; 360: 464-467
    • (1992) Nature , vol.360 , pp. 464-467
    • Pines, G.1    Danbolt, N.C.2    Bjoras, M.3
  • 46
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai Y, Hediger MA Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 1992; 360: 467-471
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 47
    • 0025251185 scopus 로고
    • Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake
    • Szatkowski M, Barbour B, Attwell D Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature 1990; 348: 443-446
    • (1990) Nature , vol.348 , pp. 443-446
    • Szatkowski, M.1    Barbour, B.2    Attwell, D.3
  • 48
    • 0025425558 scopus 로고
    • Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures
    • Kimelberg HK, Goderie SK, Higman S, Pang S, Waniewski RA Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures. J Neurosci 1990; 10: 1583-1591
    • (1990) J Neurosci , vol.10 , pp. 1583-1591
    • Kimelberg, H.K.1    Goderie, S.K.2    Higman, S.3    Pang, S.4    Waniewski, R.A.5
  • 49
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus
    • Bliss TVP, Collingridge GL A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993; 361: 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 50
    • 0023261234 scopus 로고
    • Delayed neurotoxicity of excitatory amino acids in vitro
    • Rothman SM, Thurston JH, Hauhart RE Delayed neurotoxicity of excitatory amino acids in vitro. Neuroscience 1987; 22: 471-480
    • (1987) Neuroscience , vol.22 , pp. 471-480
    • Rothman, S.M.1    Thurston, J.H.2    Hauhart, R.E.3
  • 51
    • 0026763141 scopus 로고
    • Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin
    • Monyer H, Giffard RG, Hartley DM, Dugan LL, Goldberg MP, Choi DW Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin. Neuron 1992; 8: 967-973
    • (1992) Neuron , vol.8 , pp. 967-973
    • Monyer, H.1    Giffard, R.G.2    Hartley, D.M.3    Dugan, L.L.4    Goldberg, M.P.5    Choi, D.W.6
  • 52
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden AI, Demediuk P, Panter SS, Vink R The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 1989; 244: 798-800
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 53
    • 0026649325 scopus 로고
    • Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury
    • Wrathall JR, Teng YD, Choiniere D, Mundt DJ Evidence that local non-NMDA receptors contribute to functional deficits in contusive spinal cord injury. Brain Res 1992; 586: 140-143
    • (1992) Brain Res , vol.586 , pp. 140-143
    • Wrathall, J.R.1    Teng, Y.D.2    Choiniere, D.3    Mundt, D.J.4
  • 54
    • 0021125414 scopus 로고
    • Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death
    • Rothman S Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J Neurosci 1984; 4: 1884-1891
    • (1984) J Neurosci , vol.4 , pp. 1884-1891
    • Rothman, S.1
  • 55
    • 0019347565 scopus 로고
    • Transport and metabolism of glutamate and GABA in neurons are glial cells
    • Schousboe A Transport and metabolism of glutamate and GABA in neurons are glial cells. Int Rev Neurobiol 1981; 22: 1-45
    • (1981) Int Rev Neurobiol , vol.22 , pp. 1-45
    • Schousboe, A.1
  • 56
    • 0021686831 scopus 로고
    • Alteration of striatal glutamate release after glutamine synthetase inhibition
    • Rothstein JD, Tabakoff B Alteration of striatal glutamate release after glutamine synthetase inhibition. J Neurochem 1984; 43: 1438-1446
    • (1984) J Neurochem , vol.43 , pp. 1438-1446
    • Rothstein, J.D.1    Tabakoff, B.2
  • 57
    • 0021810979 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
    • Nicklas WJ, Vyas I, Heikkila RE Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci 1985; 36: 2503-2508
    • (1985) Life Sci , vol.36 , pp. 2503-2508
    • Nicklas, W.J.1    Vyas, I.2    Heikkila, R.E.3
  • 58
    • 0026082060 scopus 로고
    • Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists
    • Turski L, Bressler K, Rettig KJ, Loschmann PA, Wachtel H Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Nature 1991; 349: 414-418
    • (1991) Nature , vol.349 , pp. 414-418
    • Turski, L.1    Bressler, K.2    Rettig, K.J.3    Loschmann, P.A.4    Wachtel, H.5
  • 59
    • 0026773766 scopus 로고
    • MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats
    • Sonsalla PK, Zeevalk GD, Manzino L, Giovanni A, Nicklas WJ MK-801 fails to protect against the dopaminergic neuropathology produced by systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice or intranigral 1-methyl-4-phenylpyridinium in rats. J Neurochem 1992; 58: 1979-1982
    • (1992) J Neurochem , vol.58 , pp. 1979-1982
    • Sonsalla, P.K.1    Zeevalk, G.D.2    Manzino, L.3    Giovanni, A.4    Nicklas, W.J.5
  • 60
    • 0027477946 scopus 로고
    • Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
    • Beal MF, Hyman BT, Koroshetz W Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? Trends Neurosci 1993; 16: 125-131
    • (1993) Trends Neurosci , vol.16 , pp. 125-131
    • Beal, M.F.1    Hyman, B.T.2    Koroshetz, W.3
  • 61
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden AI, Demediuk P, Panter SS, Vink R The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 1989; 244: 798-800
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 62
    • 0027186008 scopus 로고
    • Molecular mechanisms of trauma-induced neuronal degeneration
    • Lipton SA Molecular mechanisms of trauma-induced neuronal degeneration. Curr Opin Neurol Neurosurg 1993; 6: 588-596
    • (1993) Curr Opin Neurol Neurosurg , vol.6 , pp. 588-596
    • Lipton, S.A.1
  • 63
    • 0025874039 scopus 로고
    • Glutamate neurotoxicity in spinal cord cell culture
    • Regan RF, Choi DW Glutamate neurotoxicity in spinal cord cell culture. Neuroscience 1991; 43: 585-591
    • (1991) Neuroscience , vol.43 , pp. 585-591
    • Regan, R.F.1    Choi, D.W.2
  • 64
    • 0027207494 scopus 로고
    • Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
    • Wahlestedt C, Golanov E, Yamamoto S, Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 1993; 363: 260-263
    • (1993) Nature , vol.363 , pp. 260-263
    • Wahlestedt, C.1    Golanov, E.2    Yamamoto, S.3
  • 65
    • 0021260967 scopus 로고
    • Magnesium gates glutamate-activated channels in mouse central neurones
    • Nowak L, Bregestovski P, Ascher P, Herbet A, Prochiantz A Magnesium gates glutamate-activated channels in mouse central neurones. Nature 1984; 307: 462-465
    • (1984) Nature , vol.307 , pp. 462-465
    • Nowak, L.1    Bregestovski, P.2    Ascher, P.3    Herbet, A.4    Prochiantz, A.5
  • 66
    • 0021341121 scopus 로고
    • Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones
    • Mayer ML, Westbrook GL, Guthrie PB Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones. Nature 1984; 309: 261-263
    • (1984) Nature , vol.309 , pp. 261-263
    • Mayer, M.L.1    Westbrook, G.L.2    Guthrie, P.B.3
  • 67
    • 0026782947 scopus 로고
    • Evidence that the loss of the voltage-dependent Mg2+ block at the N-methyl-D-aspartate receptor underlies receptor activation during inhibition of neuronal metabolism
    • Zeevalk GD, Nicklas WJ Evidence that the loss of the voltage-dependent Mg2+ block at the N-methyl-D-aspartate receptor underlies receptor activation during inhibition of neuronal metabolism. J Neurochem 1992; 59: 1211-1220
    • (1992) J Neurochem , vol.59 , pp. 1211-1220
    • Zeevalk, G.D.1    Nicklas, W.J.2
  • 68
    • 0011854083 scopus 로고
    • Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801
    • Hahn JS, Aizenman E, Lipton SA Central mammalian neurons normally resistant to glutamate toxicity are made sensitive by elevated extracellular Ca2+: toxicity is blocked by the N-methyl-D-aspartate antagonist MK-801. Proc Natl Acad Sci U S A 1988; 85: 6556-6560
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 6556-6560
    • Hahn, J.S.1    Aizenman, E.2    Lipton, S.A.3
  • 69
    • 0026727807 scopus 로고
    • Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor
    • Burnashev N, Schoepfer R, Monyer H, Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science 1992; 257: 1415-1419
    • (1992) Science , vol.257 , pp. 1415-1419
    • Burnashev, N.1    Schoepfer, R.2    Monyer, H.3
  • 70
    • 0024403534 scopus 로고
    • Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation
    • Cole AJ, Saffen DW, Baraban JM, Worley PF Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 1989; 340: 474-476
    • (1989) Nature , vol.340 , pp. 474-476
    • Cole, A.J.1    Saffen, D.W.2    Baraban, J.M.3    Worley, P.F.4
  • 71
    • 0024520513 scopus 로고
    • Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation
    • Braughler JM, Hall ED Central nervous system trauma and stroke. I. Biochemical considerations for oxygen radical formation and lipid peroxidation. Free Radic Biol Med 1989; 6: 289-301
    • (1989) Free Radic Biol Med , vol.6 , pp. 289-301
    • Braughler, J.M.1    Hall, E.D.2
  • 72
    • 0027159087 scopus 로고
    • Continuous c-fos expression precedes programmed cell death in vivo
    • Smeyne RJ, Vendrell M, Hayward M, Continuous c-fos expression precedes programmed cell death in vivo. Nature 1993; 363: 166-169
    • (1993) Nature , vol.363 , pp. 166-169
    • Smeyne, R.J.1    Vendrell, M.2    Hayward, M.3
  • 73
    • 0026564448 scopus 로고
    • Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity
    • Chen H-SV, Pellegrini JW, Aggarwal SK, Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 1992; 12: 4427-4436
    • (1992) J Neurosci , vol.12 , pp. 4427-4436
    • Chen, H.-S.V.1    Pellegrini, J.W.2    Aggarwal, S.K.3
  • 74
    • 0023232903 scopus 로고
    • Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine
    • MacDonald JF, Miljkovic Z, Pennefather P Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. J Neurophysiol 1987; 58: 251-266
    • (1987) J Neurophysiol , vol.58 , pp. 251-266
    • MacDonald, J.F.1    Miljkovic, Z.2    Pennefather, P.3
  • 75
    • 0023124547 scopus 로고
    • Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity
    • Choi DW Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity. Brain Res 1987; 403: 333-336
    • (1987) Brain Res , vol.403 , pp. 333-336
    • Choi, D.W.1
  • 76
    • 0019284069 scopus 로고
    • Distribution of metabolism of the potential anti-parkinson drug memantine in the human
    • Wesemann W, Sturm G, Funfgeld EW Distribution of metabolism of the potential anti-parkinson drug memantine in the human. J Neural Transm Suppl 1980; 16: 143-148
    • (1980) J Neural Transm Suppl , vol.16 , pp. 143-148
    • Wesemann, W.1    Sturm, G.2    Funfgeld, E.W.3
  • 78
    • 0025801643 scopus 로고
    • Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate
    • Erdo SL, Schafer M Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate. Eur J Pharmacol 1991; 198: 215-217
    • (1991) Eur J Pharmacol , vol.198 , pp. 215-217
    • Erdo, S.L.1    Schafer, M.2
  • 79
    • 0023738159 scopus 로고
    • Therapeutic use of magnesium sulfate in selected cases of cerebral ischemia and seizure
    • Goldman RS, Finkbeiner SM Therapeutic use of magnesium sulfate in selected cases of cerebral ischemia and seizure. N Engl J Med 1988; 319: 1224-1225
    • (1988) N Engl J Med , vol.319 , pp. 1224-1225
    • Goldman, R.S.1    Finkbeiner, S.M.2
  • 80
    • 0008226253 scopus 로고
    • Chronic administration of nitroglycerin decreases cerebral infarct size
    • abstract.
    • Manchester KS, Jensen FE, Warach S, Lipton SA Chronic administration of nitroglycerin decreases cerebral infarct size. Neurology 1993; 43: Suppl 2: A365-A365 abstract.
    • (1993) Neurology , vol.43 , pp. A365-A365
    • Manchester, K.S.1    Jensen, F.E.2    Warach, S.3    Lipton, S.A.4
  • 81
    • 0027381484 scopus 로고
    • Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors
    • McCabe RT, Wasterlain CG, Kucharczyk N, Sofia RD, Vogel JR Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors. J Pharmacol Exp Ther 1993; 264: 1248-1252
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 1248-1252
    • McCabe, R.T.1    Wasterlain, C.G.2    Kucharczyk, N.3    Sofia, R.D.4    Vogel, J.R.5
  • 82
    • 0026742204 scopus 로고
    • A neuropharmacological evaluation of felbamate as a novel anticonvulsant
    • White HS, Wolf HH, Swinyard EA, Skeen GA, Sofia RD A neuropharmacological evaluation of felbamate as a novel anticonvulsant. Epilepsia 1992; 33: 564-572
    • (1992) Epilepsia , vol.33 , pp. 564-572
    • White, H.S.1    Wolf, H.H.2    Swinyard, E.A.3    Skeen, G.A.4    Sofia, R.D.5
  • 84
    • 0026544260 scopus 로고
    • Clinical trial of nimodipine in acute ischemic stroke
    • [Erratum, Stroke 1992;23:615.]
    • The American Nimodipine Study Group. Clinical trial of nimodipine in acute ischemic stroke. Stroke 1992; 23: 3-8 [Erratum, Stroke 1992;23:615.]
    • (1992) Stroke , vol.23 , pp. 3-8
  • 85
    • 0028097839 scopus 로고
    • A controlled trial of Riluzole in amyotrophic lateral sclerosis
    • Bensimon G, Lacomblez L, Meininger V, ALS/RILUZOLE Study Group. A controlled trial of Riluzole in amyotrophic lateral sclerosis. N Engl J Med 1994; 330: 585-591
    • (1994) N Engl J Med , vol.330 , pp. 585-591
  • 86
    • 0027474565 scopus 로고
    • Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI
    • Minematsu K, Fisher M, Li L, Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology 1993; 43: 397-403
    • (1993) Neurology , vol.43 , pp. 397-403
    • Minematsu, K.1    Fisher, M.2    Li, L.3
  • 87
    • 0023832809 scopus 로고
    • Dextromethorphan and dextrorphan as calcium channel antagonists
    • Carpenter CL, Marks SS, Watson DL, Greenberg DA Dextromethorphan and dextrorphan as calcium channel antagonists. Brain Res 1988; 439: 372-375
    • (1988) Brain Res , vol.439 , pp. 372-375
    • Carpenter, C.L.1    Marks, S.S.2    Watson, D.L.3    Greenberg, D.A.4
  • 88
    • 0026568197 scopus 로고
    • Design and baseline results of the monosialoganglioside early stroke trial: the EST Study Group
    • Rocca WA, Dorsey FC, Grigoletto F, Design and baseline results of the monosialoganglioside early stroke trial: the EST Study Group. Stroke 1992; 23: 519-526
    • (1992) Stroke , vol.23 , pp. 519-526
    • Rocca, W.A.1    Dorsey, F.C.2    Grigoletto, F.3


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