Ligand‐Induced conformational changes in the lactose permease of escherichia coli: Evidence for two binding sites

Protein Science

Volumn 3, Issue 12, 1994, Pages 2294-2301

  Wu, Jianhua ^a   Frillingos, Stathis ^a   Voss, John ^a   Ronald Kaback, H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

C less permease; ligand protein interaction; MIANS; site directed fluorescence; site directed spin labeling

Indexed keywords

ACRYLAMIDE; COUMARIN DERIVATIVE; CYSTEINE; IODIDE; LACTOSE PERMEASE; N ETHYLMALEIMIDE; SULFONIC ACID DERIVATIVE; VALINE;

ARTICLE; BINDING SITE; DISSOCIATION CONSTANT; ELECTRON SPIN RESONANCE; ENZYME CONFORMATION; ENZYME INACTIVATION; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANILINO NAPHTHALENESULFONATES; BACTERIAL PROTEINS; BINDING SITES; COMPARATIVE STUDY; COUMARINS; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; ETHYLMALEIMIDE; ISOPROPYL THIOGALACTOSIDE; LACTOSE; LIGANDS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SPECTROMETRY, FLUORESCENCE; SPIN LABELS; SUPPORT, NON-U.S. GOV'T; THIOGALACTOSIDES; VALINE;

EID: 0028587807     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.5560031214     Document Type: Article

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