Effect of cyclooxygenase inhibition on brain cell membrane lipid peroxidation during hypoxia in newborn piglets

Neonatology

Volumn 66, Issue 6, 1994, Pages 367-375

  McGowan, Jane E ^a   McGowan, Joseph C ^a   Mishra, Om P ^a   Delivoria Papadopoulos, M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain; Free radicals; Hypoxia; Indomethacin; K^{+< sup> ATPase; Na+< sup>; Newborn; NMR spectroscopy}

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); FREE RADICAL; INDOMETACIN; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN HYPOXIA; CELL MEMBRANE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; INTRAVENOUS DRUG ADMINISTRATION; LIPID PEROXIDATION; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SWINE;

ANIMAL; ANIMALS, NEWBORN; ANOXIA; BRAIN; CELL MEMBRANE; CYCLOOXYGENASE INHIBITORS; FREE RADICALS; INDOMETHACIN; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; NA(+)-K(+)-EXCHANGING ATPASE; SUPPORT, U.S. GOV'T, P.H.S.; SWINE;

EID: 0028587256     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000244130     Document Type: Article

References (33)

1. Fridovich I: Hypoxia and oxygen toxicity. Adv Neurol 1979:26:255-266.
2. Villacar A, Spatz M. Dodson RF. Com C, Bembry J: Effect of arachidonic acid on cultured cerebromi-crovascular endothelium: Permeability. lipid peroxidation and membrane 'fluidity’. Acta Neuropathol 1989;78:310-316.
3. Dean RT, Hum JV, Grant AJ, Yamamoto Y, Niki E: Free radical damage to proteins: The influence of the relative localization of radical generation, antioxidants, and target proteins. Free Rad Biol Med 1991; 11:161-168.
4. DiGiacomo JE, Pane CR, Gwiaz-dowski S, Mishra OP, Delivoria-Pa-padopoulos M: Effect of graded hypoxia on brain cell membrane injury in newborn piglets. Biol Neonate 1992:61:25-32.
5. Cino M, Del Maestro RF: Generation of hydrogen peroxide by brain mitochondria: The effect of reoxygenation following postdecapitative ischemia. Arch Biochem Biophvs 1989;269:623-638.
6. Mirro R. Armstead WM, Mirro J Jr., Busija DW, Leffler CW: Blood-in-duced superoxide anion generation on the cerebral cortex of newborn pigs. Am J Physiol 1989.257: H1560-H1564.
7. Vlessis AA, Widener LL, Bartos D: Effect of peroxide, sodium, and calcium on brain mitochondrial respiration in vitro: Potential role in cerebral ischemia and reperfusion. J Neurochem 1990:54:1412-1418.
8. Armstead WM, Mirro R, Busija DW, Leffler CW: Cerebral superoxide anion generation during seizures in newborn pigs. J Cereb Blood Flow Metab 1989:9:175-179.
9. Liu TH, Beckman JS, Freeman BA. Hogan EL, Hsu CY: Polyethylene glycol-conjugated superoxide dis-mutase and catalase reduce ischemic brain injury. Am J Physiol 1989;H589:H593.
10. Rosenberg AA, Murdaugh E, White CW: The role of oxygen free radicals in postasphyxia cerebral hypoperfusion in newborn lambs. Pedialr Res 1989;26:215-219.
11. Palmer C, Vannucci RC, Towfighi J: Reduction of perinatal hypoxic-ischemic brain damage with allopu-rinol. Pediatr Res 1990:27:332-336.
12. Mishra OP, Delivoria-Papadopou-los M: NaMC-ATPase in developing fetal guinea pig brain and the effect of maternal hypoxia. Neurochem Res 1988:13:765-770.
13. Mishra OP. Delivoria-Papadopou-los M, Cahillane G, Wagerle LC: Lipid peroxidation as the mechanism of modification of the affinity of the Na+,K+-ATPase active sites for ATP, K+,Na+. and strophanthidin in vitro. Neurochem Res 1989; 14:845-851.
14. Ikeda M, Busto R, Yoshida S, Santi-so M, Martinez E. Ginsberg MD: Cerebral phosphoinositide. triacyl-glycerol. and energy metabolism during severe hypoxia and recovery (abstract). Brain Res 1988:459:344-350.
15. Petroni A, Bertazzo A, Sarti S, Galli C: Accumulation of arachidonic acid cyclo-and lipoxygenase products in rat brain during ischemia and reperfusion: Effects of treatment with GM 1-lactone. J Neurochem 1989:53:747-752.
16. Wolfe L: Eicosanoids: Prostaglandins. thromboxanes, leukotrienes. and other derivatives of carbon-20 unsaturated fatty acids. J Neurochem 1982:38:1-14.
17. Leffler CW. Busija DW. Fletcher AM. Beasley DG. Hessler JR. Green RS: Effects of indomethacin upon cerebral hemodynamics of newborn pigs. Pediatr Res 1985; 19:1160-1164.
18. Coyle MG, Oh W, Stonestreet BS: Effects of indomethacin on brain blood flow and cerebral metabolism in hypoxic newborn piglets. Am J Physiol 1993;264:H141-H149.
19. Harik SI, Doul GH, Dick APK: Specific ouabain binding to brain microvessel and choroid plexus. J Cer-eb Blood Flow Mctab 1985:5:156-160.
20. Kovachich GB. Mishra OP: Partial inactivation of Na+,K+-ATPase in cortical brain slices in normal Krebs-Ringer phosphate medium at and 10 atm oxygen pressures. J Neurochem 1981;36:333-335.
21. Fiske CH, Subbarow Y: The colorimetric determination of phosphorus. J Biol Chem 1925;66:375-400.
22. Folch-Pi J, Lees MJ, Sloane-Stanley GH: A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 1957:226:397-409.
23. Recknagel RO, Glendc EA Jr.: Spec-trophotometric detection of lipid conjugated dienes. Methods Enzy-mol 1984;105:331-337.
24. Dillard CJ, Tappel AL: Fluorescent damage products of lipid peroxidation. Methods Enzvmol 1984:105: 337-341.
25. Yeagle P: Lipid regulation of cell membrane structure and function. FASEBJ 1989;3:1833-1842.
26. Taniguchi K, Tonomura Y: Inactivation of Na+,K+-dependent ATPase by phospholipase treatment and its reactivation by phospholipids. J Biochcm 1971:69:543-557.
27. Chan PH. Fishman RA. Longar S, Chen S, Yu A: Cellular and molecular effects of polyunsaturated fatty acids in brain ischemia and injury. Prog Brain Res 1985;63:227-235.
28. Kukreja RC. Weaver AB. Hess ML: Sarcolemmal Na+,K+-ATPase: inactivation by neutrophil-derived free radicals and oxidants. Am J Physiol 1990;259:H1330-H1336.
29. Schaeffer A, Komlos M, Seregi A: Lipid peroxidation as the cause of the ascorbic acid induced decrease of adenosine triphosphatase activities of rat brain microsomes and its inhibition by biogenic amines and psychotropic drugs. Biochem Pharmacol 1975:24:1781-1786.
30. Dempsey RJ. Roy MW, Meyer K, Cowen DE. Tai H: Development of cyclooxygenasc and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia. J Neu-rosurg 1986:64:118-124.
31. Burch RM, Wise WC, Haluschka PV: Prostaglandin-independent inhibition of calcium transport by nonsteroidal anti-inflammatory drugs: Differential effects of carbox-ylic acids and piroxicam. J Pharmacol Exp Ther 1983;227:84-91.
32. Kantor HS. Hampton M: Indomethacin in submicromolar concentrations inhibits cyclic AMP-depen-dent protein kinase. Nature 1978; 276:841-842.
33. Lees GJ: Inhibition of sodium-po-tassium-ATPase: A potentially ubiquitous mechanism contributing to central nervous system neuropathology. Brain Res Rev 1991; 16:283-300.