New insights into the local regulation of blood flow by perivascular nerves and endothelium

British Journal of Plastic Surgery

Volumn 47, Issue 8, 1994, Pages 527-543

  Burnstock, Geoffrey ^a   Ralevic, Vera ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ENDOTHELIN; NEUROTRANSMITTER; NITRIC OXIDE; PEPTIDE; PURINE DERIVATIVE; VASOACTIVE AGENT;

AGING; ATHEROSCLEROSIS; BLOOD FLOW; BLOOD VESSEL INNERVATION; BLOOD VESSEL TONE; DENERVATION; DIABETES MELLITUS; EFFERENT NERVE; ENDOTHELIUM CELL; HUMAN; HYPERTENSION; HYPOXIA; MICROVASCULATURE; NERVE FIBER; NERVE FUNCTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PLASTIC SURGERY; PRIORITY JOURNAL; REFLEX; REVIEW; SENSORY NERVE; SKIN BLOOD FLOW; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

AGING; ANIMAL; AUTONOMIC NERVOUS SYSTEM; BLOOD VESSELS; ENDOTHELIUM, VASCULAR; HUMAN; HYPERTENSION; NEURONS, AFFERENT; NEUROTRANSMITTERS; PARASYMPATHETIC NERVOUS SYSTEM; REGIONAL BLOOD FLOW; SKIN; SUPPORT, NON-U.S. GOV'T; SYMPATHETIC NERVOUS SYSTEM; VASOCONSTRICTION; VASODILATION;

EID: 0028586145     PISSN: 00071226     EISSN: 14653087     Source Type: Journal    
DOI: 10.1016/0007-1226(94)90136-8     Document Type: Article

References (274)

1. The changing face of autonomic neurotransmission
2. Autonomic neuromuscular junctions: current developments and future directions
3. Do some nerve cells release more than one transmitter?
4. Co-Transmission
5. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
6. Role of endothelium in the control of vascular smooth muscle function
7. A dual function for adenosine 5′-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular agent
8. Regulation of local blood flow by neurohumoral substances released from perivascular nerves and endothelial cells
9. Adrenergic and non-adrenergic neural control of the arterial wall
10. Co-transmission
11. Recent concepts of chemical communication between excitable cells
12. Coexistence of neuronal messengers: a new principle in chemical transmission
13. Regulation of the release of coexisting neurotransmitters
14. Functional studies of cotransmission
15. Purines as cotransmitters in adrenergic and cholinergic neurones, coexistence of neuronal messengers: a new principle in chemical transmission
16. Relative contributions of ATP and noradrenaline to the nerve evoked contraction of the rabbit jejunal artery. Dependence on stimulation parameters
17. Basic mechanisms and local modulation of nerve-impulse-induced secretion of neurotransmitters from individual sympathetic nerve varicosities
18. Sympathetic purinergic transmission in small blood vessels
19. ATP as a co-transmitter in rat tail artery
20. On pre- and/or postjunctional roles of ATP and an unknown “substance X” as sympathetic co-transmitters in rat tail artery
21. 2 purinoceptors in the isolated rabbit central ear artery
22. Electrical responses of smooth muscle cells of the rabbit ear artery to adenosine triphosphate
23. Use of reserpine and 6-hydroxy-dopamine supports evidence for purinergic cotransmission in the rabbit ear artery
24. Purinergic and non-purinergic innervation in the cerebral arteries of the dog
25. Actions of ATP and α, β-methylene ATP on neuromuscular transmission and smooth muscle membrane of the rabbit and guinea-pig mesenteric arteries
26. Noradrenaline and adenosine triphosphate as co-transmitters of neurogenic vasoconstriction in rabbit mesenteric artery
27. Evidence for sympathetic, purinergic transmission in the mesenteric artery of the dog
28. Identification of the neuroeffector transmitter in jejunal branches of the rabbit mesenteric artery
29. The electrical and mechanical basis of co-transmission in some vascular and non-vascular smooth muscles
30. Evidence for ATP as a cotransmitter in dog mesenteric artery
31. 3H]purine release from vascular adrenergic nerves: evidence for presynaptic autoinhibition
32. 338
33. A pharmacological study of the rabbit saphenous arteryin vitro: a vessel with a large purinergic contractile response to sympathetic nerve stimulation
34. Effects of reserpine and 6-hydroxydopamine on the adrenergic and purinergic components of sympathetic nerve responses of the rabbit saphenous artery
35. Evidence for noradrenergic-purinergic cotransmission in the hepatic artery of the rabbit
36. Acta Physiologica ScandinavicaCentennial
37. An analysis of the purinergic component of active muscle vasodilation obtained by electrical stimulation of the hypothalamus in rabbits
38. Adrenergic and purinergic neurotransmission in arterial resistance vessels of the cat intestinal circulation
39. Renal periarterial nerve stimulation-induced vasoconstriction at low frequencies is primarily due to release of a purinergic transmitter in the rat
40. Sympathetic purinergic vasoconstriction and thermosensitivity in a canine cutaneous vein
41. Blockade of vasopressor and vas deferens responses by α, β-methylene ATP in the pithed rat
42. 2X receptors in the pithed rat
43. The contributions of noradrenaline and ATP to the responses of the rabbit central ear artery to sympathetic nerve stimulation depend on the parameters of stimulation
44. Vasoconstriction of guinea-pig submucosal arterioles following sympathetic nerve stimulation is mediated by the release of ATP
45. Differential blockade of ATP, noradrenaline and electrically evoked contractions of the rat vas deferens by nifedipine
46. Regulation of voltage-dependent excitatory responses to α, β-methylene ATP, ATP and non-adrenergic nerve stimulation by dihydropyridines in the guinea-pig vas deferens
47. 2-purinoceptors mediate both vasodilatation (via the endothelium) and vasoconstriction of the isolated rat femoral artery
48. ATP causes postjunctional potentiation of noradrenergic contractions in the portal vein of guinea pig and rat
49. Postjunctional synergism of noradrenaline and adenosine 5′-triphosphate in the mesenteric arterial bed of the rat
50. High levels of neuropeptide Y in peripheral noradrenergic neurons in various mammals including man
51. Guanethidine-sensitive release of neuropeptide Y-like immunoreactivity in the cat spleen by sympathetic nerve stimulation
52. Neuropeptide Y—a cotransmitter with noradrenaline and adenosine 5′-triphosphate in the sympathetic nerves of the mouse vas deferens? A biochemical, physiological and electropharmacological study
53. Frequency- and reserpine-dependent chemical coding of sympathetic transmission. Differential release of noradrenaline and neuropeptide Y from pig spleen
54. Mechanisms underlying pre- and postjunctional effects of neuropeptide Y in sympathetic vascular control
55. Evidence for different pre- and postjunctional receptors for neuropeptide Y and related peptides
56. Neuropeptide Y potentiates purinergic as well as adrenergic responses of the rabbit ear artery
57. Overview: purinergic mechanisms
58. Sympathetic noradrenergic neurons containing dynorphin but not neuropeptide Y innervate small cutaneous blood vessels of guinea-pigs
59. Immunohistochemical demonstration of serotonin in nerves supplying human cerebral and mesenteric blood vessels: some speculations about their involvement in vascular disorders
60. 5-Hydroxytryptamine demonstrated immunohistochemically in rat cerebrovascular nerves largely represents 5-hydroxytryptamine uptake into sympathetic nerve fibres
61. Vasoactive intestinal polypeptide in relation to atropine resistant vasodilatation in the submaxillary gland of the cat
62. Characteristics of the axonal transport of vasoactive intestinal polypeptide (VIP) in nerves of the cat
63. Corelease of vasoactive intestinal polypeptide and peptide histidine isoleucine in relation to atropine resistant vasodilatation in cat submandibular salivary gland
64. Neuropeptide Y-like immunoreactivity in rat cranial parasympathetic neurons: coexistence with vasoactive intestinal peptide and choline acetyltransferase
65. Target specificity of neuropeptide Y-immunoreactive cranial parasympathetic neurones
66. Peptides and vasomotor mechanisms
67. Nitric oxide, a novel neuronal messenger
68. Co-localization of calcitonin gene-related peptide-like immunoreactivity with substance P in cutaneous, vascular and visceral sensory neurons of guinea-pigs
69. Innervation of the feline cerebral vasculature by nerve fibres containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P
70. Distribution of calcitonin gene-related peptide in the rat peripheral nervous system with special reference to coexistence with substance P
71. Coexistence of substance P and calcitonin gene-related peptide-like immunoreactivities in sensory nerves in relation to cardiovascular and bronchoconstrictor effects of capsaicin
72. Peptides in the mammalian cardiovascular system
73. Ultrastructural evidence for the coexistence of calcitonin gene-related peptide and substance P in secretory vesicles of peripheral nerves in the guinea pig
74. ATP excites a subpopulation of rat dorsal horn neurones
75. Excitation of single sensory neurones in the rat caudal trigeminal nucleus by iontophoretically applied adenosine 5′-triphosphate
76. Is ATP a central synaptic mediator for certain primary afferent fibres from mammalian skin?
77. Cationic channels activated by extracellular ATP in rat sensory neurons
78. The sensory-efferent function of capsaicin-sensitive sensory nerves
79. Pathway-specific patterns of coexistence of substance P, calcitonin gene-related peptide, cholecystokinin and dynorphin in neurons of the dorsal root ganglia of the guinea-pig
80. Substance P in the cerebral vasculature: depletion by capsaicin suggests a sensory role
81. Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs
82. Substance P-containing nerve fibres in large peripheral blood vessels of the rat
83. Calcitonin gene-related peptide-immunoreactive nerves in the tongue, epiglottis and pharynx of the rat: occurrence, distribution and origin
84. Calcitonin gene-related peptide (CGRP) in capsaicin-sensitive substance P-immunoreactive sensory neurons in animals and man: distribution and release by capsaicin
85. Autonomic neuroeffector junctions—reflex vasodilatation of the skin
86. Antidromic vasodilatation and neurogenic inflammation
87. Neurohumoral control of blood vessels: some future directions
88. Substance P regulates the vasodilator activity of calcitonin gene-related peptide
89. Potentiation of tachykinin-induced protein extravasation by calcitonin gene-related peptide
90. Prejunctional modulation of sensory-motor nerve mediated vasodilation of the rat mesenteric arterial bed by adenosine
91. 1 subtype
92. Differential effects of neuropeptide Y and opioids on neurogenic responses of the perfused rat mesentery
93. Prejunctional modulation of sensory-motor nerve-mediated vasodilatation of the rat mesenteric arterial bed by opioid peptides
94. NPY modulates neurotransmission of CGRP-containing vasodilator nerves in rat mesenteric arteries
95. Adrenergic modulation of calcitonin gene-related peptide (CGRP)-containing nerve-mediated vasodilation in the rat mesenteric resistance vessel
96. Neuropeptide Y-like immunoreactivity in cultured intrinsic neurones of the heart
97. Intrinsic neurones and associated cells of the guinea-pig heart in culture
98. Sympathetic and nonsympathetic neuropeptide Y-containing nerves in the rat myocardium and coronary arteries
99. Nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in a subpopulation of intrinsic neurones of the guinea pig heart
100. Nitrergic transmission: nitric oxide as a mediator of non-adrenergic, non-cholinergic neuro-effector transmission
101. Comparison of endothelium dependent relaxation and nitric oxide induced relaxation in rabbit aorta
102. Endothelium-derived relaxing factor from pulmonary artery and vein possess pharmacologic and chemical properties identical to those of nitric oxide radical
103. Vascular endothelial cells synthesize nitric oxide from L-arginine
104. Heterogeneity of endothelium-dependent responses in mammalian blood vessels
105. Role of endothelium in responses of vascular smooth muscle
106. 2-purinoceptor?
107. Local purinergic regulation of blood pressure
108. Flow effects on prostacyclin production by cultured human endothelial cells
109. Prostacyclin production by cultured endothelial cell monolayers exposed to step increases in shear stress
110. Mechanism of shear-induced prostacyclin production in endothelial cells
111. Flow-induced release of endothelium-derived relaxing factor.
112. Endothelial cells are involved in the vasodilatory response to hypoxia
113. The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia
114. The effect of hypoxia on prostaglandin output and on tone in isolated coronary arteries
115. 2) mediates hypoxic relaxation of bovine coronary artery strips
116. Endothelial-dependent relaxant actions of carbachol and substance P in the arterial smooth muscle
117. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels
118. Endothelium-dependent hyperpolarization of canine coronary smooth muscle
119. Endothelium-derived hyperpolarizing factor: a new endogenous inhibitor from the vascular endothelium
120. Purinergic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: role of the endothelium
121. Ultrastructural localization of choline acetyltransferase in vascular endothelial cells in rat brain
122. Release of vasoactive substances from endothelial cells
123. Vascular control by purines with emphasis on the coronary system
124. Ultrastructural localisation of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries
125. Serotonin is localized in endothelial cells of coronary arteries and released during hypoxia: a possible new mechanism for hypoxia-induced vasodilatation of the rat heart
126. Ultrastructural localisation of substance P and choline acetyltransferase in endothelial cells of rat coronary artery and release of substance P and acetylcholine during hypoxia
127. Localization of vasopressin, serotonin and angiotensin II in endothelial cells of the renal and mesenteric arteries of the rat
128. Localization of arginine-vasopressin in endothelial cells of rat pulmonary artery
129. Colocalization of endothelin, vasopressin and serotonin in cultured endothelial cells of rabbit aorta
130. Localization of neuropeptide Y and atrial natriuretic peptide in the endothelial cells of human umibilical blood vessels
131. Identification of immunoreactive substance P in human and other mammalian endothelial cells
132. Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensin
133. Histidine decar☐ylase activities of bovine aortic endothelium and intima-media
134. Release of ATP from perfused heart during coronary vasodilatation
135. Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclo-oxygenase inhibition
136. Endothelium-dependent flow-induced dilation of canine femoral and saphenous arteries
137. Role of endothelium in the control of arterial diameter by blood flow
138. Flow-induced release of endothelium-derived relaxing factor.
139. Flow-dependent dilation in myograph-mounted resistance artery segments
140. Substance P is released from the endothelium of normal and capsaicin-treated rat hindlimb vasculature, in vivo, by increased flow
141. A new protocol for removal of the endothelium from the perfused rat hind-limb preparation
142. Endothelial cells cultured from human umbilical vein release ATP, substance P and acetylcholine in response to altered shear stress
143. Flow-induced release of adenosine 5′-triphosphate from endothelial cells of the rat mesenteric arterial bed
144. Anoxia and endothelium-dependent reactivity of the canine femoral artery
145. Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium
146. Endothelium-dependent contractions to stretch in canine basilar arteries
147. Endothelium-dependent contraction to stretch in canine basilar arteries.
148. Potassium-Induced Endothelium-Dependent Rhythmic Activity in the Canine Basilar Artery
149. Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?
150. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
151. Endothelin induces potent microvascular constriction
152. Endothelin is a potent constrictor of isolated human resistance arteries
153. Release of EDRF by endothelin in the rat isolated perfused mesentery
154. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
155. Characteristics of pressor response to endothelin in spontaneously hypertensive and Wistar Kyoto rats
156. Endothelin-1
157. Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells
158. Localization of endothelin receptors in rat kidney
159. Autoradiographic localisation of endothelin binding sites in human and porcine coronary arteries
160. Endothelin and ATP but not vasopressin are released from isolated aortic endothelial cells exposed to increased flow
161. Maintenance of “basal” vascular tone may represent a physiological role for endothelin
162. Development of microcirculation: capillary growth and adaptation
163. The pharmacology of the efferent function of sensory nerves
164. Development and ageing of perivascular adrenergic nerves in the rabbit. A quantitative fluorescence histochemical study using image analysis
165. An increase in the expression of neuropeptidergic vasodilator, but not vasoconstrictor, cerebrovascular nerves in aging rats
166. Increased density of perivascular nerves to the major cerebral vessels of the spontaneously hypertensive rat: differential changes in noradrenaline and neuropeptide Y during development
167. Perivascular noradrenergic and peptide-containing nerves show different patterns of changes during development and ageing in the guinea-pig
168. Neuropeptides and a neuronal marker in cutaneous innervation during human foetal development
169. Changes in calcitonin gene-related peptide (CGRP)-containing vasodilator nerve activity in hypertension
170. Age-related decrease of calcitonin gene-related peptide-containing vasodilator innervation in the mesenteric resistance vessel of the spontaneously hypertensive rat
171. Effect of age on vascular content of calcitonin gene-related peptide and mesenteric vasodilator nerve activity in the rat
172. Neurogenic responses following topical application of capsaicin in man
173. Microvascular skin responses in elderly people with varicose leg ulcers
174. Experiments on cerebrovascular nerve plasticity and trophic vascular adaption in young and adult rats
175. Increase in SP-like immunoreactivity in nerve fibres of rabbit iris and ciliary body one to four months following sympathetic denervation
176. The effect of sympathectomy on calcitonin gene-related peptide levels in the rat trigeminovascular system
177. Co-existence of immunoreactivity to neuropeptide Y and vasoactive intestinal polypeptide in non-adrenergic axons innervating guinea-pig cerebral arteries after sympathectomy
178. Marked increases in calcitonin gene-related peptide-containing nerves in the developing rat following long-term sympathectomy with guanethidine
179. Effect of oestrogen and progesterone on noradrenergic nerves and on nerves showing serotonin-like immunoreactivity in the basilar artery of the rabbit
180. Dual vasoconstrictor and vasodilator innervation of the uterine arterial supply in guinea-pig
181. The peptidergic innervation of the guinea pig uterine artery in pregnancy
182. Altered endothelium-mediated relaxation after denervation of growing rabbit ear artery
183. The effect of perivascular denervation on endothelium-dependent relaxation to acetylcholine
184. 2 and 5-HT in vitro
185. Ultrastructural changes in the cerebral artery wall induced by long-term sympathetic denervation
186. The sympathetic nervous system and atherosclerosis
187. CGRP- and NPY-like immunoreactivity in endothelial cells after long-term stimulation of perivascular nerves
188. Changes in purinergic responses of the rabbit isolated central ear artery after chronic electrical stimulationin vivo
189. Intimal thickening and the distribution of vasomotor nerves in the mechanically injured dog coronary artery
190. NPY immunoreactivity in experimental hypertension (aorta ligated and DOCA treated rats)
191. A comparison of substance P innervation of the mesenteric vascular bed in hypertensive and normotensive rats
192. Peptide-containing nerves around blood vessels of stroke-prone spontaneously hypertensive rats
193. Neuropeptides in hypertension: role of neuropeptide Y and calcitonin gene related peptide.
194. Differential effects of α, β-methylene ATP on responses to nerve stimulation in SHR and WKY tail arteries
195. Evidence for increased purinergic contribution in hypertensive blood vessels exhibiting co-transmission
196. Diminished purinergic modulation of the vascular adrenergic neurotransmission in spontaneously hypertensive rats
197. 3H]norepinephrine release from perfused mesenteric arteries of SHR and renal hypertensive rats
198. 1-receptors in caudal arteries of spontaneously hypertensive rats
199. Hypertensive structural changes in blood vessles: Do endothelial cells hold the key?
200. Endothelium-dependent and independent relaxation of aortic rings from hypertensive rats.
201. Reactivity of aorta and mesenteric microvessels to drugs in spontaneously hypertensive rats: role of the endothelium
202. Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension
203. Changes in vascular reactivity in experimental diabetic rats: comparison with hypothyroid rats
204. Adrenergic nerve function and contractile activity of the caudal artery of the streptozotocin diabetic rat
205. Vasoactive intestinal polypeptide-like immunoreactive nerves in diabetic penis: a comparison between streptozotocin-treated rats and man
206. Changes in the VIPergic, cholinergic and adrenergic innervation of human penile tissue in diabetic and non-diabetic impotent males
207. Dysfunctional penile cholinergic nerves in diabetic impotent men
208. Reduction of nerves containing vasoactive intestinal polypeptide and serotonin, but not neuropeptide Y and catecholamine, in cerebral blood vessels of the 8-week streptozotocin-induced diabetic rat
209. Early increase in CGRP- and VIP-immunoreactive nerves in the skin of streptozotocin-induced diabetic rats
210. Impaired sensory-motor nerve function in the isolated mesenteric arterial bed of streptozotocin-diabetic and ganglioside-treated streptozotocin-diabetic rats
211. Impaired Neurogenic and Endothelium-Mediated Relaxation of Penile Smooth Muscle from Diabetic Men with Impotence
212. Endothelium-dependent relaxation in aorta of BB rat
213. Attenuation of endothelium-dependent relaxation in aorta from diabetic rats
214. Selective impairment of endothelium-dependent relaxation by oxygen-derived free radicals
215. Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats
216. Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats
217. Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus.
218. Impairment of endothelium-dependent dilatation of the basilar artery during diabetes mellitus
219. Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats
220. Combined clinical and pathological study of peripheral arterial disease
221. Diabetes, hyperglycemia and arterial diseases
222. Atherosclerosis in persons with hypertension and diabetes mellitus
223. Cholesterol feeding attenuates endothelium-dependent relaxation response to acetylcholine in the main pulmonary artery of chickens
224. Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates
225. Effect of hypercholesterolemia on vascular reactivity in the rabbit I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits
226. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries
227. Videomicroscopic demonstration of defective cholinergic arteriolar vasodilation in atherosclerotic rabbit
228. Mechanisms of abnormal endothelium-dependent vascular relaxation in atherosclerosis: implications for altered autocrine and paracrine functions of EDRF
229. Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis
230. Restoration of endothelium-dependent relaxation by dietary lipid treatment of atherosclerosis
231. Endothelium-dependent relaxation and experimental atherosclerosis in the rabbit aorta
232. Dual control by nerves and endothelial cells of arterial blood flow in atherosclerosis
233. Sex and age as factors influencing the vascular reactivity in Watanabe heritable hyperlipidaemic (WHHL) rabbits: a pharmacological and morphological study of the hepatic artery
234. 2 consumption in man during acute exposure to high altitude
235. Serial studies of heart rate, blood pressure and urinary catecholamine excretion on acute induction to high altitude (3658M)
236. Sympathoadrenal responses to acute and chronic hypoxia in the rat
237. The effect of continued hypoxia on rat pulmonary arterial circulation: an ultrastructural study
238. Age and sex influence on pulmonary hypertension of chronic hypoxia and on recovery
239. Scanning electron microscopy of pulmonary vascular endothelium in rats with hypoxia-induced hypertension
240. Effect of chronic hypoxia on endothelium-dependent relaxation and cGMP content in rat pulmonary artery
241. Chronic hypoxia changes the ratio of endothelin to ATP release from rat aortic endothelial cells exposed to high flow
242. Trigeminal antidromic vasodilatation and plasma extravasation in the rat: effects of sensory, autonomic and motor denervation
243. Plasma protein extravasation induced by mammalian tachykinins in rat skin: influence of anaesthetic agents and an acetylcholine antagonist
244. Neurogenic vasodilation in the rat hairy skin measured using a laser doppler flowmeter
245. Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene-related peptide in rat skin microvasculature
246. The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves
247. Action of adenosine triphosphate on mast cells in normal and denervated skin
248. Evidence for endothelium-dependent and endothelium-independent vasodilation in human skin flaps
249. Participation of nitric oxide in the mustard oil-induced neurogenic inflammation of the rat paw skin
250. Evidence that endogenous nitric oxide modulates oedema formation induced by substance P
251. Modulation of acute inflammation by endogenous nitric oxide
252. L-arginine therapy in Raynaud's phenomenon?
253. Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis
254. Potent vasoactive properties of endothelin 1 in human skin
255. Further studies on the actions of endothelin-1 on blood flow in human skin
256. Endothelin reduces blood flow in experimental skin flaps
257. Endothelin-1 induces a histamine-dependent flare in vivo, but does not activate human skin mast cells in vitro
258. Endothelin-1 in human skin: immunohistochemical, receptor binding, and functional studies
259. Endothelin-1 in human skin: immunolocalization, receptor binding, mRNA expression, and effects on cutaneous microvascular endothelial cells
260. Characterization of endothelin-binding sites in human skin and their regulation in primary Raynaud's phenomenon and systemic sclerosis
261. Impaired neurogenic vascular response in patients with diabetes and neuropathic foot lesions
262. Non-invasive tests of neurovascular function: reduced responses in diabetes mellitus
263. Microcirculation and diabetes
264. Microangiopathy in human diabetic neuropathy
265. Microangiopathy in human diabetic neuropathy: relationship between capillary abnormalities and the severity of neuropathy