A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 91, Issue 19, 1994, Pages 8969-8973

  Fodde, Riccardo ^a   Edelmann, Winfried ^b   Yang, Kan ^c   Van Leeuwen, Claus ^a   Carlson, Christine ^b   Renault, Beatrice ^a,b   Breukel, Cor ^a   Alt, Elaine ^b   Lipkin, Martin ^c   Khan, P Meera ^a   Kucherlapati, Raju ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

animal model for human disease; colorectal cancer; gene targeting

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COLON CARCINOGENESIS; COLON POLYPOSIS; COLORECTAL CANCER; EMBRYO; GENE MUTATION; GENE TARGETING; INTESTINE TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ANIMAL; BASE SEQUENCE; DNA PRIMERS; GENES, LETHAL; INTESTINAL NEOPLASMS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA;

EID: 0028567875     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.91.19.8969     Document Type: Article

References (33)