Neurotoxicity of glucocorticoids in the primate brain

Hormones and Behavior

Volumn 28, Issue 4, 1994, Pages 336-348

  Uno, Hideo ^a,b   Eisele, Steve ^a   Sakai, Akiko ^a   Shelton, Steve ^c   Baker, Eva ^d   DeJesus, Onofre ^d   Holden, James ^d  

^a UNIVERSITY OF WISCONSIN   (United States)

^b Department of Pathology ^*  (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d CancerCare Manitoba   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0028567422     PISSN: 0018506X     EISSN: None     Source Type: Journal    
DOI: 10.1006/hbeh.1994.1030     Document Type: Article

References (22)

1. Collaborative Group on Antenatal Steroid Therapy. (1984). Effects of antenatal dexa-methasone administration in the infant: Long-term follow-up. J. Pediat. 104, 259-267.
2. Gould, E., Woolley, C. S., and McEwen, B. S. (1991). Adrenal steroids regulate postnatal development of the rat dentate gyrus: I. Effects of glucocorticoids on cell death. J. Comp. Neurol. 313, 479-485.
3. Dunn, J. D., and Orr, S. E. (1984). Differential plasma corticosterone responses to hippocampal stimulation. Exp. Brain Res. 54, 1-6.
4. Horner, H., Packan, D., and Sapolsky, R. (1990). Glucocorticoids inhibit glucose transport in cultured hippocampal neurons and glia. Neuroendocrinoiogy 52, 57.
5. Howard, E. (1968). Reduction in size and total DNA of cerebrum and cerebellum in adult mice after corticosterone treatment in infancy. Exp. Neurol. 22, 191-208.
6. Jack, C. R., Bentley, M. D., Twomey, C. K., and Zinsmeister, A. R. (1990). MR Imaging-based volume measurements of the hippocampal formation and anterior temporal lobe: validation studies. Radiology 176, 205-209.
7. Jensen, T. S., Genefke, I. K., Hyldebrandt, N., Pedersen, H., Petersen, H. D., and Weile, B. (1982). Cerebral atrophy in young torture victims. N. Engt. J. Med. 307, 1341.
8. Jerome, C. P., and Hendrickx, A. G. (1988). Comparative teratogenicity of triamcinolone acetonide and dexamethasone in the rhesus monkey. (Macaca mulatto). J. Med. Pri-matol. 17, 195-203.
9. McEwen, B., Chao, H., Spencer, R., Brinton, R., Maclsaac, L., and Harrelson, A. (1987). Corticosteroid receptors in brain: Relationship of receptors to effects in stress and aging, In W. F. Ganong (Ed.), The Hypothalamic-Pituitary Adrenal Axis Revisited. Ann. NY Acad. Sei. Vol. 512, pp. 394-401.
10. McEwen, B. S., Wallach, G., and Magnus, C. (1974). Corticosterone binding to hippocampus: Immediate and delayed influences of the absence of adrenal secretion. Brain Res. 70, 321.
11. McEwen, B. S., Weiss, J., and Schwartz, L. (1968). Selective retention of corticosterone by limbic structures in rat brain. Nature 220, 911-912.
12. Rakic, P., and Nowakowski, R. S. (1981). The time of origin of neurons in the hippocampal region of the rhesus monkey. J. Comp. Neurol. 196, 99-128.
13. Sapolsky, R. M. (1992). Stress, the Aging Brain, and the Mechanisms of Neuron Death. The MIT Press, Cambridge, MA.
14. Sapolsky, R. M., Uno, H., Rebert, C. S., and Finch, C. E. (1990). Hippocampal damage associated with prolonged glucocorticoid exposure in primates. J. Neurosci. 10, 2897-2902.
15. Sapolsky, R. M., Zola-Morgan, S., and Squire, L. R. (1991). Inhibition of glucocorticoid secretion by the hippocampal formation in the primate. J. Neurosci. 11, 3695-3704.
16. Sloviter, R. S., Valiquette, G., Abrams, G. M., Ronk, E. C., Sollas, A. I., Paul, L. A., and Neubort, S. L. (1989). Selective loss of hippocampal granule cells in the mature rat brain after adrenalectomy. Science 243, 535-538.
17. Söusa, R. J., Tannery, N. H., and Lafer, E. M. (1989). In situ hybridization mapping of glucocorticoid receptor messenger ribonucleic acid in rat brain. Mol. Endocrinol. 3, 481-494.
18. Starkman, M. N., Gebarski, S. S., Berent, S., and Schteingart, D. E. (1992). Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing’s Syndrome. Biol. Psychiatry 32, 756-765.
19. Uno, H., Lohmiller, L., Thieme, C., Kemnitz, J. W., Engle, M. J., Roecker, E. B., and Farrell, P. M. (1990). Brain damage induced by prenatal exposure to dexamethasone in fetal rhesus macaques. Dev. Brain Res. 53, 157-167.
20. Uno, H., Tarara, R., Else, J. G., Suleman, M. A., and Sapolsky, R. M. (1989). Hippocampal damage associated with prolonged and fatal stress in primates. J. Neurosci. 9, 1705-1711.
21. Uno, H., Thieme, C., Alsum, P., Richardson, R., and Houser, W. D. (1991). Incidence of senile plaque in brains of aged rhesus monkeys. Lab Investigation 64, 103A.
22. Zachman, R. D. (1982). The NIH multicenter study and miscellaneous clinical trials of antenatal corticosteroid administration. In Lung Development: Biological and Clinical Perspectives, Vol. II, pp. 275-296. Academic Press, San Diego.