The structures of rnase a complexed with 3′‐CMP and d(CpA): Active site conformation and conserved water molecules

Protein Science

Volumn 3, Issue 12, 1994, Pages 2322-2339

  Zegers, Ingrid ^a   Maes, Dominique ^a   Dao‐Thi, Minh‐Hoa ^a   Wyns, Lode ^a   Poortmans, Freddy ^b   Palmer, Rex ^c  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

3 CMP complex; conserved solvent sites; d(CpA) complex; downstream binding; ribonuclease A mechanism; S peptide

Indexed keywords

ASPARAGINE; CYTIDINE PHOSPHATE; DEOXYADENOSINE; DEOXYCYTIDYLYL 3',5' DEOXYADENOSINE; HISTIDINE; LYSINE; RIBONUCLEASE A; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

BINDING SITES; COMPARATIVE STUDY; CRYSTALLOGRAPHY, X-RAY; CYTIDINE MONOPHOSPHATE; HYDROGEN BONDING; MODELS, MOLECULAR; NUCLEOTIDES; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN CONFORMATION; PYRIMIDINES; RIBONUCLEASE T1; RIBONUCLEASE, PANCREATIC; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; WATER;

EID: 0028564999     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.5560031217     Document Type: Article

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