Acute Subdural Hematoma: Is the Blood Itself Toxic?

Journal of Neurotrauma

Volumn 11, Issue 6, 1994, Pages 669-678

  Duhaime, Ann Christine ^a   Gennarelli, Laura M ^a   Yachnis, Anthony ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BLOOD CLOTTING; BRAIN INFARCTION; BRAIN INJURY; CELL DEATH; CONTROLLED STUDY; HISTOLOGY; NONHUMAN; PARIETAL LOBE; RAT; SUBDURAL HEMATOMA; TOXICITY;

ANIMAL; BLOOD PHYSIOLOGY; BRAIN ISCHEMIA; CELL DEATH; DISEASE MODELS, ANIMAL; HEMATOMA, SUBDURAL; INJECTIONS; MALE; PARIETAL LOBE; RATS; SUBARACHNOID HEMORRHAGE; SUBDURAL SPACE;

EID: 0028564669     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.1994.11.669     Document Type: Article

References (21)

1. BULLOCK, R., and TOJISAWA, H. (1992). The role of glutamate antagonists for the treatment of CNS injury. J. Neurotrauma 9(Suppl. 2), S443-S473.
2. BULLOCK, R., BUTCHER, S., and MCCULLOCH, J. (1990). Changes in extracellular glutamate concentration after acute subdural haematoma in the rat-evidence for an “excitotoxic” mechanism? Acta Neurochir. Suppl. (Wien) 51, 274-276.
3. BULLOCK, R., BUTCHER, S.P., CHEN, M., KENDALL, L., and MCCULLOCH, J. (1991). Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat. J. Neurosurg. 74, 794-802.
4. CHEN, M.S., BULLOCK, R., GRAHAM, D.I., MILLER, J.D., and MCCULLOCH, J. (1991). Ischemic neuronal damage after acute subdural hematoma in the rat: effects of pretreatment with a glutamate antagonist. J. Neurosurg. 74, 944-950.
5. CHOI, D.W. (1987). Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7(2), 369-379.
6. DUHAIME, A.C., GENNARELLI, L., YACHNIS, A., and ROSS, D.T. (1993). Experimental acute subdural hematoma: variations on a theme. J. Neurotrauma 10(Suppl. 1), SI50.
7. FINDLAY, J.M., MACDONALD, R.L., and WEIR, B.K. (1991). Current concepts of pathophysiology and management of cerebral vasospasm following aneurysmal subarachnoid hemorrhage, Cerebrovasc. Brain Metab. Rev. 3(4), 336-361.
8. HAINES, D.E., HARKEY, H.L., and AL-MEFTY, O. (1993). The “subdural” space: a new look at an outdated concept. Neurosurgery 32, 111-120.
9. INGLIS, P., KURODA, Y., and BULLOCK, R. (1992). Glucose hypermetabolism after acute subdural hematoma is ameliorated by a competitive NMDA antagonist. J. Neurotrauma 9(2), 75-84.
10. JACKOWSKI, A., CROCKARD, A., BURNSTOCK, G., ROSS RUSSELL, R., and KRISTEK, F. (1990). The time course of intracranial pathophysiological changes following experimental subarachnoid haemorrhage in the rat. J. Cereb. Blood How Metab. 10(6), 835-849.
11. JENKINS, L.W., MOSZYNSKI, K., LYETH, B.G., et al. (1989). Increased vulnerability to the mildly traumatized rat brain to cerebral ischemia: the use of controlled secondary ischemia as a research tool to identify common or different mechanisms contributing to mechanical and ischemic brain injury. Brain Res. 477, 211-224.
12. KURODA, Y., and BULLOCK, R. (1992a). Failure of cerebral blood flow-metabolism coupling after acute subdural hematoma in the rat. Neurosurgery 31(6), 1062-1071.
13. KURODA, Y., and BULLOCK, R. (1992b). Local cerebral blood flow mapping before and after removal of acute subdural hematoma in the rat. Neurosurgery 30, 687-691.
14. MACDONALD, R.L., WEIR, B.K.A., RUNZER, T.D., et al. (1991). Etiology of cerebral vasospasm in primates. J. Neurosurg. 75, 415-424.
15. MARATICO, F., GAETANI, P., CAFE, C., SPANU, G., and RODRIGUEZ YBAENA, R. (1993). Antioxidant enzymatic activities after experimental subarachnoid hemorrhage in rats. Acta NeuroL Scand. 87(1), 62-66.
16. MELER, J.D., BULLOCK, R., GRAHAM, D.I., CHEN, M.H., and TEASDALE, G.M. (1990). Ischemic brain damage in a model of acute subdural hematoma. Neurosurgery 27, 433-439.
17. PETERSON, J.W., KWUN, B., HACKETT, J.D., and ZERVAS, N.T. (1990). The role of inflammation in experimental cerebral vasospasm. J. Neurosurg. 72, 767-774.
18. SCHRODER, M.L., MUIZELAAR, J.P., and KUTA, A.J. (1994). Documented reversal of global ischemia immediately after removal of an acute subdural hematoma. Report of two cases. J. Neurosurg. 80(2), 324-327.
19. TAKENAKA, K., YAMADA, H., SAKAI, N., ANDO, T., NAKASHIMA, T., and NISHIMURA, Y. (1991). Induction of cytosolic free calcium elevation in rat vascular smooth-muscle cells by cerebrospinal fluid from patients after subarachnoid hemorrhage. J. Neurosurg. 75, 452-457.
20. TIETZ, N.W. (ed) (1986). Textbook of Clinical Chemistry. W.B. Saunders, Philadelphia.
21. VOLLMER, D.G., KONGO, K., OGAWA, H., TSUKAHARA, T., and KASSELL, N.F. (1991). A study of the effectiveness of the iron-chelating agent deferoxamine as vasospasm prophylaxis in a rabbit model of subarachnoid hemorrhage. Neurosurgery 28(1), 27-32.