Functional significance of different human cyplal genotypes

Carcinogenesis

Volumn 15, Issue 12, 1994, Pages 2961-2963

  Crofts, F ^a   Taioll, E ^a   Trachman, J ^a   Cosma, G N ^a,b   Currie, D ^a   Toniolo, P ^a   Garte, S J ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450;

ARTICLE; CANCER RISK; ENZYME ACTIVE SITE; ENZYME ACTIVITY; GENE EXPRESSION; GENE INDUCTION; GENETIC POLYMORPHISM; HUMAN; LUNG CANCER; POINT MUTATION; PRIORITY JOURNAL; SMOKING;

ADULT; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; COMPARATIVE STUDY; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; EXONS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMAN; LUNG NEOPLASMS; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; POLYMORPHISM (GENETICS); POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RACIAL STOCKS; SMOKING; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC;

EID: 0028557312     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/15.12.2961     Document Type: Article

References (23)

1. Gonzalez, FJ., Jaiswal, A.K. and Nebert, D.W. (1987) P450 genes evolution, regulation, and relationship to human cancer. In Cold Spring Harbor Symposia on Quantitative Biology: Molecular Biology of Homo Sapiens. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
2. Guengerich, F.P. and Lieber, D.C. (1985) Enzymatic activation of chemicals to toxic metabolites. Crit. Rev. Toxicol., 14, 259-307
3. Kouri, R.T., McKinney, C.E., Slomiany, DJ., Snodgrass, D.R., Wray K.P. and McLemore, T.L. (1982) Positive correlation between high AHH activity and primary lung cancer as analyzed in cryopreserved lymphocytes. Cancer Res., 42, 5030-5037
4. Kellerman, G., Shaw, C.R. and Luyten-Kellerman, M. (1973) Aryl hydrocarbon hydroxylase inducibility and bronchogenic carcinoma. N. Engl J. Med., 289, 934-937
5. Kellerman, G., Luyte-Kellerman, M. and Shaw, C.R. (1973) Genetic variation of aryl hydrocarbon hydroxylase in human lymphocytes. Am. J. Hum. Genet., 25, 327-331
6. Trell, L., Korsgaad, R., Janzon, X. and Trell, E. (1985) Distribution and reproducibility of aryl hydrocarbon hydroxylase inducibility in a prospective study of middle-aged male smokers and nonsmokers. Cancer, 56, 1988-1994
7. Petersen, D.D., McKinney, C.E., Ikeya, K., Smith, H.H., Bale A E., McBride, O.W. and Nebert, D.W. (1991) Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP. Am. J. Hum. Genet., 48, 720-725
8. Cosma, G., Crofts X-., Currie, D., Toniolo, P. and Garte, SJ. (1993) The relationship between genotype and function of the human CYP1A1 gene. J. Toxicol Environ. Health, 40, 315-322
9. Hayashi, S.-I., Watanabe, J., Nakachi, K. and Kawajiri, K. (1991) Genetic linkage of lung-cancer-associated Mspl polymorphism with amino acid replacement in the heme binding region of the human cytochrome P4501A1 gene. J. Biochem., 110, 407-411
10. Hirvonen, A., Husgafvel-Pursiainen, K., Karjalainen, A., Anttila, S. and Vainio, H. (1992) Point-mutational Mspl and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiol Biomark. Prevent., 1, 485-489
11. Kawajiri, K., Nakachi, K., Imai, K., Yoshii, A., Shinoda JX and Watanabe, J. (1990) Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome p4501Al gene. FEBS Lett., 263, 131-133
12. Tefre, T., Ryber, D., Haugn, A., Nebert, D.W., Skaug, V., Brogger, A. and Borrcsen, A.-L. (1991) Human CYP1A1 (cytochrome Pl-450) gene: lack of association between the Mspl restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics, 1, 20-25
13. Shields, P.G., Caporaso, N.E., Falk, R.T., Sugimura, H., Trivers, G.E., Trump, B.F., Hoover, R.N., Weston A. and Harris, C.C. (1993) Lung cancer, race, and a CYP1A1 genetic polymorphism. Cancer Epidemiol Biomark. Prevent., 2, 481-485
14. Sugimura XL, Suzuki, I., Hamada, G.S., Iwase, T., Takahashi, T., Nagura, K., Iwata, H., Watanabe, S., Kino, I. and Tsugane, S. (1994) Cytochrome P450 1A1 genotype in lung cancer patients and controls in Rio de Janeiro, Brazil. Cancer Epidemiol Biomark. Prevent., 3, 145-148
15. Cosma, G., Crofts, F., Currie, D., Wirgin, I., Toniolo, P. and Garte, SJ. (1993) Racial differences in restriction fragment length polymorphisms and messenger RNA inducibility of the human CYP1A1 gene. Cancer Epidemiol. Biomark. Prevent., 2, 53-57
16. Crofts, F., Cosma, G.N., Taioli, E., Currie, D.C., Toniolo, P.T. and Garte, SJ. (1993) A novel CYP1A1 gene polymorphism in African-Americans. Carcinogenesis, 14, 1729-1731
17. Chomczynski, P. and Sacchi P. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem., 162, 156-159
18. Thompson, C.L., McCoy JZ, Lambert, J.M., An dries, MJ. and Lucier, G.W. (1989) Relationship among benzo-a-pyrene metabolism, benzo-a-pyrene-diolepoxide:DNA adduct formation and sister chromatid exchanges in human lymphocytes from smokers and nonsmokers. Cancer Res., 49, 6503-6511
19. Brad ford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein—dye binding. Anal. Biochem., 72, 248-254
20. Jaiswal A K., Gonzalez, FJ. and Nebert, D.W. (1985) Human P —450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism. Nucleic Acids Res., 13, 4503-4520
21. Amsbaugh, S.C., Din J.-H., Swan, D.C., Popescu P.C. and Chen, Y.-T. (1986) Expression and chromosomal localization of the cytochrome P -450 gene in human mitogen-stimulated lymphocytes. Cancer Res., 46, 2423-2327
22. Landi, M.T., Bertazzi, P.A., Clark, G., Lucier, G.W., Garte, SJ., Cosma, G., Shields, P.G. and Caporaso, N.E. (1993) Susceptibility markers in normal subjects: A pilot study for the investigation of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin related diseases. Chemosphere, 27, 375-381
23. Kawajiri, K., Nakachi, K., Imai, K., Watanabe, J. and Hayashi, S.-I. (1993) The CYP1A1 gene and cancer susceptibility. Rev. Oncol Hematol, 14, 77-87