A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo

Nature

Volumn 372, Issue 6507, 1994, Pages 695-698

  Liuzzi, Michel ^a   Déziel, Robert ^a   Moss, Nell ^a   Beaulieu, Pierre ^a   Bonneau, Anne Marie ^a   Bousquet, Christiane ^a   Chafouleas, James G ^a   Garneau, Michel ^a   Jaramillo, Jorge ^a   Krogsrud, Richard L ^a   Lagacé, Lisette ^a   McCollum, Robert S ^a   Nawoot, Sopone ^a   Guindon, Yvan ^a  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMINO ACID; ANTIVIRUS AGENT; BILD 1263; RIBONUCLEOTIDE REDUCTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESISTANCE; ENZYME INHIBITION; ENZYME SUBUNIT; FEMALE; HERPES SIMPLEX VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION; VIRUS KERATITIS; VIRUS REACTIVATION; VIRUS REPLICATION; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; ANIMAL; ANTIVIRAL AGENTS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; HAMSTERS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; KERATITIS, DENDRITIC; MICE; MICE, INBRED BALB C; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; RIBONUCLEOTIDES; VIRUS REPLICATION;

EID: 0028556688     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/372695a0     Document Type: Article

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