Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages

Bioorganic and Medicinal Chemistry

Volumn 2, Issue 9, 1994, Pages 939-947

  Wai, John S ^a   Bamberger, Dona L ^a   Fisher, Thorsten E ^a   Graham, Samuel L ^a   Smith, Robert L ^a   Gibbs, Jackson B ^a   Mosser, Scott D ^a   Oliff, Allen I ^a   Pompliano, David L ^a   Rands, Elaine ^a   Kohl, Nancy E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGOPEPTIDE; P21(RAS) FARNESYL PROTEIN TRANSFERASE; P21(RAS) FARNESYL-PROTEIN TRANSFERASE; TRANSFERASE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL STRAIN 3T3; CHEMICAL STRUCTURE; MOLECULAR GENETICS; MOUSE; ONCOGENE RAS; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VIRUS CELL TRANSFORMATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMAL; CELL TRANSFORMATION, VIRAL; GENES, RAS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOPEPTIDES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFERASES;

EID: 0028509497     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)82043-X     Document Type: Article

References (20)