Absence of B7-dependent responses in CD28-deficient mice

Immunity

Volumn 1, Issue 6, 1994, Pages 501-508

  Green, Jonathan M ^a   Noel, Patricia J ^b   Sperling, Anne I ^b   Walunas, Theresa L ^b   Gray, Gary S ^c   Bluestone, Jeffrey A ^b   Thompson, Craig B ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c REPLIGEN CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CTLA-4; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; INTERLEUKIN 2;

ANIMAL; ANTIGEN PRESENTING CELL; ARTICLE; CHO CELL; HAMSTER; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOUSE; MOUSE MUTANT; MOUSE STRAIN; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMAL; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, CD80; ANTIGENS, DIFFERENTIATION; CHO CELLS; CRICETULUS; HAMSTERS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0028500255     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/1074-7613(94)90092-2     Document Type: Article

References (27)

1. B70 antigen is a second ligand for CTLA-4 and CD28
2. Functional expression of B7/BB1 on activated T lymphocytes
3. Differential regulatory signals delivered by antibody binding to the CD28 (Tp44) molecule during the activation of human T lymphocytes
4. Costimulation of T lymphocytes with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 induces functional expression of CTLA-4, a second receptor for B7
5. B7, a B cell-restricted antigen that identifies preactivated B cells
6. Selective induction of B7/BB-1 on interferon-y stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway
7. CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation: expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production
8. Cloning of B7-2: a CTLA-4 counterreceptor that costimulates human T cell proliferation
9. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2
10. T cell receptor stimulation, but not CD28 costimulation, is dependent on LFA-1-mediated events
11. CD28-mediated signalling co-stimulates murine T cells and prevents induction of energy in T-cell clones
12. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location
13. Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody
14. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg
15. Characterization of CTLA-4 structure and expression in human T cells
16. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1
17. CTLA-4 is a second receptor for the B cell activation antigen B7
18. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes
19. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
20. Low affinity interaction of peptide-MHC complexes with T cell receptors
21. A cell culture model for T lymphocyte clonal anergy
22. Differential T cell costimulatory requirements in CD28deficient mice
23. Expression and function of B7 on human epidermal langerhans cells
24. Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1
25. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
26. Synergy between cyclosporin A and a monoclonal antibody to B7 in blocking alloantigen-induced T-cell activation
27. CTLA-4 can function as a negative regulator of T cell activation