A quantitative analysis of shear effects on cell suspension and cell culture of perilla frutescens in bioreactors

Biotechnology and Bioengineering

Volumn 44, Issue 5, 1994, Pages 649-654

  Zhong, Jian‐Jiang ^a,b   Fujiyama, Kazuhito ^a   Seki, Tatsuji ^a   Yoshida, Toshiomi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

anthocyanin production; bioreactor cultivation; metabolism; Perilla frutescens; plant cell culture; secondary; shear effects

Indexed keywords

BATCH CELL CULTURE; BIOREACTORS; GROWTH KINETICS; METABOLISM; METABOLITES; PLANT CELL CULTURE; SHEAR STRESS; SUSPENSIONS (FLUIDS);

CELL SUSPENSION; CELL VIABILITY; PERILLA FRUTESCENS; ROTATING DRUM REACTOR; SHEAR EFFECTS;

CELLS;

ANTHOCYANIN;

ARTICLE; BIOREACTOR; CELL CULTURE; METABOLISM; NONHUMAN; PLANT CELL; SHEAR STRESS;

PERILLA FRUTESCENS;

EID: 0028483695     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.260440512     Document Type: Letter

References (28)

1. The prediction of power consumption in the agitation of non‐Newtonian fluids
2. Hydrodynamic effects on animal cells grown in microcarrier cultures
3. Production of shikonin derivatives by plant cell cultures (in Japanese)
4. Effect of shear stress on xanthan gum production
5. Effect of oxygen supply on the suspension culture of genetically modified tobacco cells
6. Effect of agitational shear on growth and protease production by Thermomonospora fusa
7. Response of plant tissue culture to a high shear environment
8. Development of a helical‐ribbon impeller bioreactor for high‐density plant cell suspension culture
9. Effect of bioreactor design and agitator speed on the growth and alkaloid accumulation by cultures of Catharanthus roseus
10. Dielectric spectroscopy as a novel and convenient tool for the study of the shear sensitivity of plant cells in suspension culture
11. Shear effects on suspended cells
12. Agitation of viscous Newtonian and non‐Newtonian fluids
13. Protection mechanisms of freely suspended animal cells (CRL 8018) from fluid‐mechanical injury. Viscometric and bioreactor studies using serum, pluronic F68 and polyethylene glycol
14. A model system for evaluating shear in the design of stirred fermentors
15. Hydrodynamic shear stress and mass transport modulation of endothelial cell metabolism
16. Fluid‐mechanical damage of animal cells in bioreactors
17. The sensitivity of biocatalysts to hydrodynamic shear stress
18. Large scale fermentation and alkaloid production of cell suspension cultures of Catharanthus roseur
19. Effect of shear on the viability of plant cell suspensions
20. Development of a strategy to control the dissolved concentration of oxygen and carbon dioxide at constant shear in a plant cell bioreactor
21. Inhibition of microbial growth and metabolism by excess turbulence
22. Studies on the reduction of 2,3,5‐triphenylterazolium chloride as a viability assay for plant tissue cultures
23. Effect of light irradiation on anthocyanin production by suspended culture of Perilla frutescens
24. Production of red pigments by Perilla frutescens cells in bioreactors
25. Rheological characteristics of cell suspension and cell culture of Perilla frutescens
26. Enhancement of anthocyanin production by Perilla frutescens cells in a stirred bioreactor with internal light irradiation