Reactive oxygen species generation and human spermatozoa: The balance of benefit and risk

BioEssays

Volumn 16, Issue 4, 1994, Pages 259-267

  Aitken, John ^a   Fisher, Helen ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; MEMBRANE LIPID; REACTIVE OXYGEN METABOLITE;

ACROSOME; CELL MEMBRANE; CYTOLOGY; FEMALE; FERTILIZATION; HUMAN; LEUKOCYTE; LIPID PEROXIDATION; MALE; MALE INFERTILITY; METABOLISM; PHYSIOLOGY; REVIEW; SPERM; SPERMATOZOON; SPERMATOZOON CAPACITATION;

ACROSOME; ANTIOXIDANTS; CELL MEMBRANE; FEMALE; FERTILIZATION; HUMAN; INFERTILITY, MALE; LEUKOCYTES; LIPID PEROXIDATION; MALE; MEMBRANE LIPIDS; REACTIVE OXYGEN SPECIES; SEMEN; SPERM CAPACITATION; SPERMATOZOA;

EID: 0028409709     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.950160409     Document Type: Review

References (60)

1. Biological defence mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent
2. Enzymic mechanisms of superoxide production
3. Identification of a superoxide generating system in human fibroblasts
4. 2 generation catalysed by thyroid plasma membranes
5. The role of oxygen in the metabolism and motility of human spermatozoa
6. Formation of hydrogen peroxide by spermatozoa and its inhibitory effect on respiration
7. Metabolism of spermatozoa and its effects on motility and survival
8. Spontaneous lipid peroxidation in rabbit epididymal spermatozoa: its effect on sperm motility
9. Lipid peroxidation and the reactions of superoxide and hydrogen peroxide in mouse spermatozoa
10. Generation of reactive oxygen species by human spermatozoa
11. Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa
12. Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa
13. Lipid peroxidation in spermatozoa
14. Capacitation, Acrosome Reaction and Fertilisation
15. A potential fusion peptide and an integrin ligand domain in a protein active in sperm oocyte fusion
16. Iron, ferritin and copper in seminal plasma
17. Reactive oxygen species generated by human netrophils inhibit sperm motilty: protective effect of seminal plasma and scavengers
18. Analysis of the relationship between reactive oxygen species procuction and leucocyte infiltration in fractions of human semen spearated on Percoll gradients
19. Formation of reactive oxygen species in spermatozoa of infertile patients
20. On the contribution of leucocytes and spermatozoa to the high levels of reactive oxygen species recorded in the ejaculates of oligozoospermic patients
21. Origin of reactive oxygen species in human semen: spermatozoa or leucocytes?
22. Reactive oxygen species and human spermatozoa: I. Effects on the motility of intact spermatozoa and on sperm axonemes
23. Reactive oxygen species and human spermatoza: II. Depletion of adenosine triphophate (ATP) plays an important role in the inhibition of sperm motility
24. Use of a xanthine oxidase free radical generating system of investigate the cytotoxic effects of reactive oxygen species on human spermatozoa
25. Analysis of lipid peroxidation mechanisms in human spermatozoa
26. 2 with unsaturated fatty acits
27. Biologically relevant metal iondependent hydroxyl radical generation
28. Preliminary communication: possible role of reactive nitrogen intermediates in leucocyte‐mediated sperm dysfuction
29. Peroxidative breakdown of phospholipids in human psermatozoa, spermicidal properties of fatty acid peroxides, and protective action of seminal plasma
30. Properties of spermatozoal superoxide dismutase and lack of involvement of superoxides in the metal‐ion‐catalyzed lipidperoxidation reactions in semen
31. Reactive oxygen species in semen of infertile patients: levels of superoxide dismutase‐ and catalase‐like activities in seminal plasma and spermatozoa
32. Epididymal secretory glutathione peroxidase is encoded by an androgen regulated transcript which does not contain a selenocysteine codon
33. Isolation and characterization of a rat cDNA clone encodinga a secreted superoxide dismutase reveals the epididymis to be a major site of its expression
34. Analysis of the protiens in human seminal plasma
35. The antigens of human seminal plasma
36. Components of human split ejaculates. I. Spermatozoa, fructose, immunoglobulins, albumin, lactoferrin, transferrin and other plasma proteins
37. Generation of reactive oxygen species, lipid peroxidation, and human sperm function
38. Content of significant amounts of a cytotoxic end‐product of lipid peroxidation in human semen
39. 2+‐ATPase activity of the intestinal brush border membranes
40. Relationship between ironcatalysed lipid peroxidation potential and human sperm function
41. Alteration of oxygen uptake and the redox state of ubiquinone in rabbit sperm exposed to a variety of physiologic treatments
42. Sperm creatine phosphokinase activity as a measure of sperm quality in normospermic, variospermic and oligospermic men
43. Human sperm hyperactivation and capacitation as part of an oxidative process
44. Human sperm hyperactivation in whole semen and its association with low superoxide scavenging capacity in seminal plasma
45. 2 on capactitation
46. Hydrogen peroxide is involved in hamster sperm caacitation in vitro
47. 2 and vanadate in vitro
48. Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction
49. 95 kD sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding
50. Regulation of mouse gamaete interaction by a sperm tyrosine kinase
51. Role of membrane phosphotyrosine proteins in human spermatozoal function
52. Sueroxide anion increased intracellular pH, intracellular free calcium, and arachidonate release in human cells
53. Evidence for the activation of phospholipase during the acrosome reaction of human sperm elicited by calcium ionophore A23187
54. 2
55. 2‐mediated arachiodonic‐acid release in cultured intestinal epthelial cells
56. Siginficance of reactive oxygen species and anti‐oxidants in defining the efficacy of sperm perparation techniques