Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds

Journal of Clinical Investigation

Volumn 94, Issue 1, 1994, Pages 79-88

  Saarialho Kere, Ulpu K ^a   Pentland, Alice P ^b   Birkedal Hansen, Henning ^c   Parks, William C ^a   Welgus, Howard G ^a  

^a BARNES JEWISH HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

keratinocytes; metalloproteinases; stromelysin; ulcers; wound healing

Indexed keywords

COLLAGENASE; MESSENGER RNA; STROMELYSIN;

ARTICLE; CELL MIGRATION; CELL SUBPOPULATION; COLLAGEN METABOLISM; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; WOUND HEALING;

EID: 0028363393     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI117351     Document Type: Article

References (40)

1. McCachren, S. S. 1991. Expression of metalloproteinases and metalloproteinase inhibitor in human arthritic synovium. Arthritis Rheum. 34:1085-1093.
2. Pelletier, J. P., M. P. Faure, J. A. DiBattista, S. Wilhelm, D. Visco, and J. Martel-Pelletier. 1993. Coordinate synthesis of stromelysin, interleukin-1, and oncogene proteins in experimental osteoarthritis. An immunohistochemical study. Am. J. Pathol. 146:95-105.
3. Matrisian, L. M. 1990. Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet. 6:121-125.
4. Chin, J. R., G. Murphy, and Z. Werb. 1985. Stromelysin, a connective tissue degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. J. Biol. Chem. 260:12367-12376.
5. Muller, D., B. Quantin, M.-C. Gesnel, R. Millon-Collard, J. Abecassis, and R. Breathnach. 1988. The collagenase gene family in humans consists of at least four members. Biochem. J. 253:187-192.
6. Windsor, L. J., H. Grenett, B. Birkedal-Hansen, M. K. Bodden, J. A. Engler, and H. Birkedal-Hansen. 1993. Cell type-specific regulation of SL-1 and SL-2 genes. Induction of the SL-2 gene but not the SL-1 gene by human keratinocytes in response to cytokines and phorbol esters. J. Biol. Chem. 268:17341-17347.
7. Sirum, K. L., and C. E. Brinckerhoff. 1989. Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. Biochemistry 28:8691-8698.
8. Murphy, G., M. I. Cockett, R. V, Ward, and A. J. P. Docherty. 1991. Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 75 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP). Biochem. J. 277:277-279.
9. Brinckerhoff, C. E., K. L. Sirum-Connolly, M. J. Karmilowicz, and D. Auble. 1992. Expression of stromelysin and stromelysin-2 in rabbit and human fibroblasts. Matrix. 1 (Suppl.):165-175.
10. Saarialho-Kere, U. K., E. S. Chang, H. G. Welgus, and W. C. Parks. 1992. Distinct localization of collagenase and TIMP expression in wound healing associated with ulcerative pyogenic granuloma. J. Clin. Invest. 90:1952-1957.
11. Saarialho-Kere, U. K., S. O. Kovacs, A. P. Pentland, J. E. Olerud, H. G. Welgus, and W. C. Parks. 1993. Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J. Clin. Invest. In press.
12. Murphy, G., M. I. Cockett, P. E. Stephens, B. J. Smith, and A. J. P. Docherty. 1987. Stromelysin is an activator of procollagenase. Biochem. J. 248:265-268.
13. He, C. S., S. M. Wilhelm, A. P. Pentland, B. L. Manner, G. A. Grant, A. Z. Eisen, and G. I. Goldberg. 1989. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc. Natl. Acad. Sci. USA. 86:2632-2636.
14. Prosser, I. W., K. R. Stenmark, M. Suthar, E. C. Crouch, R. P. Mecham, and W. C. Parks. 1989. Regional heterogeneity of elastin and collagen gene expression in intralobar arteries in response to hypoxic pulmonary hypertension as demonstrated by in situ hybridization. Am. J. Pathol. 135:1073-1088.
15. Goldberg, G. I., S. M. Wilhelm, A. Kronberger, E. A. Bauer, G. A. Grant, and A. Z. Eisen. 1986. Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J. Biol. Chem. 261:6600-6605.
16. Saus, J., S. Quinones, Y. Otani, H. Nagase, E. D. Harris, and M. Kurkinen. 1988. The complete primary structure of human matrix metalloproteinase-3. J. Biol. Chem. 263:6742-6745.
17. Saarialho-Kere, U. K., E. S. Chang, H. G. Welgus, and W. C. Parks. 1993. Expression of interstitial collagenase, 92 kDa gelatinase, and TIMP-1 in granuloma annulare and necrobiosis lipoidica diabeticorum. J. Invest. Dermatol. 100:335-342.
18. Wilhelm, S. M., I. E. Collier, A. Kronberger, A. Z. Eisen, B. L. Manner, G. A. Grant, E. A. Bauer, and G. I. Goldberg. 1987. Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc. Natl. Acad. Sci. USA. 84:6725-6729.
19. Saarialho-Kere, U. K., H. G. Welgus, and W. C. Parks. 1993. Divergent mechanisms regulate interstitial collagenase and 92 kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J. Biol. Chem. 268:17354-17361.
20. Parks, W. C., H. Secrist, L. C. Wu, and R. P. Mecham. 1988. Developmental regulation of tropoelastin isoforms. J. Biol. Chem. 263:4416-4423.
21. Pentland, A. P., S. C. Jacobs, M. Mahoney, and M. J. Holzman. 1990. Ultraviolet light potentiates histamine-induced release of prostaglandin in cultured human keratinocytes: a mechanism for irradiation erythema. J. Clin. Invest. 86:566-574.
22. Shapiro, S. D., E. J. Campbell, D. K. Kobayashi, and H. G. Welgus. 1990. Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-γ. J. Clin. Invest. 86:1204-1210.
23. Ståhle-Bäckdahl, M., and W. C. Parks. 1993. 92 kDa gelatinase is actively expressed by eosinophils and secreted by neutrophils in invasive squamous cell carcinoma. Am. J. Pathol. 142:995-1000.
24. Pulford, K. A. F., E. M. Rigney, K. J. Micklem, W. P. Stross, K. C. Gatter, and D. Y. Mason. 1989. KPl: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections. J. Clin. Pathol. 42:414-421.
25. Cooper, T. W., E. A. Bauer, and A. Z. Eisen. 1982. Enzyme-linked immunosorbent assay for human skin collagenase. Collagen Relat. Res. 3:205-211.
26. Hasty, K. A., T. F. Pourmotabbed, G. I. Goldberg, T. J. P., D. G. Spinella, R. M. Stevens, and C. L. Mainardi. 1990. Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases. J. Biol. Chem. 265:11421-11424.
27. Ståhle-Bäckdahl, M., B. D. Sudbeck, A. Z. Eisen, H. G. Welgus, and W. C. Parks. 1992. Expression of 92 kDa type IV collagenase by eosinophils associated with basal cell carcinoma. J. Invest. Dermatol. 99:497-503.
28. Werb, Z., P. M. Tremble, O. Behrendtsen, E. Crowley, and C. H. Damsky. 1989. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol. 109:877-889.
29. Herron, G. S., Z. Werb, K. Dwyer, and M. J. Banda. 1986. Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity. J. Biol. Chem. 261:2810-2813.
30. Welgus, H. G., E. J. Campbell, J. D. Cury, A. Z. Eisen, R. M. Senior, S. M. Wilhelm, and G. I. Goldberg. 1990. Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J. Clin. Invest. 86:1496-1502.
31. Stenn, K. S., and R. Malhotra. 1992. Epithelialization. In Wound Healing: Biochemical and Clinical Aspects. I. K. Cohen, R. F. Diegelmann, and W. J. Lindblad, Editors. W. B. Saunders Co., Philadelphia. 115-127.
32. Pellegrini, G., M. De Luca, G. Orecchia, F. Balzac, O. Cremona, P. Savoia, R. Cancedda, and P. C. Marchisio. 1992. Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin. J. Clin. Invest. 89:1783-1795.
33. Symington, B. E., Y. Takada, and W. G. Carter. 1993. Interaction of integrins α3β1 and α2β1: potential role in keratinocyte intercellular adhesion. J. Cell Biol. 120:523-535.
34. MacNaul, K. L., N. Chartrain, M. Lark, M. J. Tocci, and N. I. Hutchinson. 1990. Discoordinate expression of stromelysin, collagenase and tissue inhibitor of metalloproteinases-1 in rheumatoid synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-α on stromelysin expression. J. Biol. Chem. 265:17238-17245.
35. Frisch, S. M., and H. E. Ruley. 1987. Transcription from the stromelysin promoter is induced by interleukin-1 and repressed by dexamathasone. J. Biol. Chem. 262:16300-16304.
36. Matrisian, L. M., N. Gleichenhaus, M. C. Gesnel, and R. Breathnach. 1985. Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO (Eur. Mol. Biol. Organ.) J. 4:1435-1440.
37. Kerr, L. D., J. T. Holt, and L. M. Matrisian. 1988. Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science (Wash. DC). 242:1424-1427.
38. Matrisian, L. M. 1992. The matrix-degrading metalloproteinases. BioEssays. 14:455-463.
39. Edwards, D. R., G. Murphy, J. J. Reynolds, S. E. Whitham, A. J. P. Docherty, P. Angel, and J. K. Heath. 1987. Transforming growth factor modulates the expression of collagenase and metalloproteinase inhibitor. EMBO (Eur. Mol. Biol. Organ.) J. 6:1899-1904.
40. Unemori, E. N., M. J. Bair, E. A. Bauer, and E. P. Amento. 1991. Stromelysin expression regulates collagenase activation in human fibroblasts. J. Biol. Chem. 266:23477-23482.