NMR-Derived Solution Conformations of a Hybrid Synthetic Peptide Containing Multiple Epitopes of Envelope Protein gp120 from the RF Strain of Human Immunodeficiency Virus

Biochemistry

Volumn 33, Issue 8, 1994, Pages 2055-2062

  de Lorimier, Robert ^a,b   Moody, M Anthony ^a,c   Haynes, Barton F ^a,c   Spicer, Leonard D ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Departments of Radiation Oncology and Radiology   (United States)

^c Duke Center for Translational Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENVELOPE PROTEIN; EPITOPE; GLYCOPROTEIN GP 120; NEUTRALIZING ANTIBODY;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOGENICITY; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; CROSS-LINKING REAGENTS; DISULFIDES; EPITOPES; HIV; HIV ENVELOPE PROTEIN GP120; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028355519     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00174a011     Document Type: Article

References (59)

1. Abergel, C., Loret, E., & Claverie, J.-M. (1989) Eur. J. Immunol. 19, 1969-1972.
2. Bax, A., & Davis, D. G. (1985) J. Magn. Reson. 65, 355-360.
3. Beale, D., & Feinstein A. (1976) Q. Rev. Biophys. 9, 135-180.
4. Cease, K. B., Margalit, J., Cornette, J. L., Putney, S. D., Robey, W. G., Ouyang, C., Streicher, H. Z., Fischinger, P. J., Gallo, R. C., DeLisi, C., & Berzofsky, J. A. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 4249-4253.
5. Chandrasekhar, K., Profy, A. T., & Dyson, H. J. (1991) Biochemistry 30, 9187-9194.
6. Dadaglio, G., Leroux, A., Langlade-Demoyen, P., Bahraoui, E. M.,Traincard, F., Fisher, R., & Plata, F. (1991) J. Immunol. 147, 2302-2309.
7. DeLisi, C., & Berzofsky, J. A. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 7048-7052.
8. Dyson, H. J., & Wright, P. E. (1991) Annu. Rev. Biophys. Biophys. Chem. 20, 519-538.
9. Dyson, H. J., Cross, K. J., Houghten, R. A., Wilson, I. A., Wright, P. E., & Lerner, R. A. (1985) Nature 318, 480-483.
10. Dyson, H. J., Lerner, R. A., & Wright, P. E. (1988a) Annu. Rev. Biophys. Biophys. Chem. 17, 305-374.
11. Dyson, H. J., Ranee, M., Houghten, R. A., Wright, P. E., & Lerner, R. A. (1988b) J. Mol. Biol. 201, 201-217.
12. Dyson, H. J., Ranee, M., Houghten, R. A., Lerner, R. A., & Wright, P. E. (1988c) J. Mol. Biol. 201, 161-200.
13. Dyson, H. J., Satterthwait, A. C., Lerner, R. A., & Wright, P. E. (1990) Biochemistry 29, 7828-7837.
14. Dyson, H. J., Norrby, E., Hoey, K., Parks, D. E., Lerner, R. A., & Wright, P. E. (1992a) Biochemistry 31, 1458-1463.
15. Dyson, H. J., Sayre, J. R., Merutka, G., Shin, H.-C., Lerner, R. A., & Wright, P. E. (1992b) J. Mol. Biol. 226, 819-835.
16. Falk, K., Rötzschke, O., Stevanovic, S., Jung, G., & Rammensee, H.-G. (1991) Nature 351, 290-296.
17. Germain, R. N., & Margulies, D. H. (1993) Annu. Rev. Immunol. 11, 403-450.
18. Goudsmit, J., Debouck, C., Meloen, R. H., Smit, L., Bakker, M., Asher, D. M., Wolff, A. V., Gibbs, C. J., Jr., & Gajdusek, D. C. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 4478-4482.
19. Gras-Masse, H., Jolivet, M., Drobecq, H., Aubert, J. P., Beachey, E. H., Audibert, F., Chedid, L., & Tartar, A. (1988) Mol. Immunol. 25, 673-678.
20. Hart, M. K., Palker, T. J., Matthews, T. J., Langlois, A. J., Lerche, N. W., Martin, M. E., Scearce, R. M., McDanal, C., Bolognesi, D. P., & Haynes, B. F. (1990) J. Immunol. 145, 2677-2685.
21. Hart, M. K., Weinhold, K. J., Scearce, R. M., Washburn, E. M., Clark, C. A., Palker, T. J., & Haynes, B. F. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 9448-9452.
22. Haynes, B. F., Torres, J. V., Langlois, A. J., Bolognesi, D. P., Gardner, M. B., Palker, T. J., Scearce, R. M., Jones, D. M., Moody, M. A., McDanal, C., & Matthews, T. J. (1993) J. Immunol. 151, 1646-1653.
23. Ho, D. D., Sarngadharan, M. G., Hirsch, M. S., Schooley, R. T., Rota, T. R., Kennedy, R. C., Chanh, T. C., & Sato, V. L. (1987) J. Virol. 61, 2024-2028.
24. Jeener, J., Meier, B. H., Bachmann, P., & Ernst, R. R. (1979) J. Phys. Chem. 71, 4546-4553.
25. Lark, L. R., Berzofsky, J. A., & Gierasch, L. M. (1989) Peptide Res. 2, 314-321.
26. LaRosa, G. J., Davide, J. P., Weinhold, K., Waterbury, J. A., Profy, A. T., Lewis, J. A., Langlois, A. J., Dreesman, G. R., Boswell, R. N., Shadduck, P., Holley, L. H., Karplus, M., Bolognesi, D. P., Matthews, T. J., Emini, E. A., & Putney, S. (1990) Science 249, 932-935.
27. Lasky, L. A., Nakamura, G., Smith, D. H., Fennie, C., Shimasaki, C., Patzer, E., Berman, P., Gregory T., & Capon, D. J. (1987) Cell 50, 975-985.
28. Lerner, R. A. (1984) Adv. Immunol. 36, 1-44.
29. Levitt, M. H., Freeman, R., & Frenkiel, T. (1982) J. Magn. Reson. 47, 328-330.
30. Maddon, P. J., Dalgleish, A. G., McDougal, J. S., Clapham, P. R., Weiss, R., & Axel, R. (1986) Cell 47, 333-348.
31. Margalit, H., Spouge, J. L., Cornette, J. L., Cease, K. B., DeLisi, C., & Berzofsky, J. A. (1987) J. Immunol. 138, 2213-2229.
32. Ni, F., Ripoll, D. R., & Purisima, E. O. (1992) Biochemistry 31, 2545-2554.
33. Osterhout, J. J., Baldwin, R. L., York, E. J., Stewart, J. M., Dyson, H. J., & Wright, P. E. (1989) Biochemistry 28, 7059-7064.
34. Palker, T. J., Clark, M. E., Langlois, A. J., Matthews, T. J., Weinhold, K. J., Randall, R. R., Bolognesi, D. P., & Haynes, B. F. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 1932-1936.
35. Palker, T. J., Matthews, T. J., Langlois, A., Kim, J. E., Berzofsky, J. A., Bolognesi, D. P., & Haynes, B. F. (1989a) UCLA Symp. Mol. Cell. Biol., New Ser. 119.
36. Palker, T. J., Matthews, T. J., Langlois, A., Tanner, M. E., Martin, M. E., Scearce, R. M., Kim, J. E., Berzofsky, J. A., Bolognesi, D. P., & Haynes, B. F. (1989b) J. Immunol. 142, 3612-3619.
37. Piantini, U., Sørensen, O. W., & Ernst, R. R. (1982) J. Am. Chem. Soc. 104, 6800-6801.
38. Ranee, M., Sørensen, O. W., Bodenhausen, G., Wagner, G., Ernst, R. R., & Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 117, 479-485.
39. Ratner, L., Haseltine, W., Patarca, R., Livak, K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., Ivanoff, L., Petteway, S. R., Pearson, M. L., Lautenberger, J. A., Papas, T. S., Ghrayeb, J., Chang, N. T., Gallo, R. C., & Wong-Stahl, F. (1985) Nature 313, 277-284.
40. Rothbard, J., & Taylor, W. (1988) EMBO J. 7, 93-100.
41. Rothbard, J. B., Lechler, R. I., Howland, K., Bal, V., Eckels, D. D., Sekaly, R., Long, E. O., Taylor, W. R., & Lamb, J. R. (1988) Cell 52, 515-523.
42. Rusche, J. R., Javaherian, K., McDanal, C., Petro, J., Lynn, D. L., Grimaila, R., Langlois, A., Gallo, R. C., Arthur, L. O., Fischinger, P. J., Bolognesi, D. P., Putney, S. D., & Matthews, T. J. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 3198-3202.
43. Schrier, R. D., Gnann, J. W., Jr., Landes, R., Lockshin, C., Richman, D., McCutchan, A., Kennedy, C., Oldstone, H. B. A., & Nelson, J. A. (1989) J. Immunol. 142, 1166-1176.
44. Segal, D. M., Padlan, E. A., Cohen, G. H., Rudikoff, S., Potter, M., & Davies, D. R. (1974) Proc. Natl. Acad. Sci. U.S.A. 71, 4298-4302.
45. Shirai, M., Pendelton, C. D., Ahlers, J., Takeshita, T., Newman, M., & Berzofsky, J. A. (1994) J. Immunol. 152, 549-556.
46. Spouge, J. L., Guy, H. R., Cornett, J. L., Margalit, H., Cease, K., Berzofsky, J. A., & DeLisi, C. (1987) J. Immunol. 138, 204-212.
47. Starcich, B. R., Hahn, B. H., Shaw, G. M., McNeely, P. D., Modrow, S., Wolff, H., Parks, E. S., Josephs, S. F., Gallo, R. C., & Wong-Staal, F. (1986) Cell 45, 637-648.
48. Sun, N.-C., Ho, D. D., Sun, C. R. Y., Liou, R.-S., Gordon, W., Fung, M.S.-C., Li, X.-L., Ting, R. C., Lee, T.-H., Chang, N. T., & Chang, T.-W. (1989) J. Virol. 63, 3579-3585.
49. Takahashi, H., Cohen, J., Hosmalin, A., Cease, K. B., Houghten, R., Cornette, J. L., DeLisi, C., Moss, B., Germain, R. N., & Berzofsky, J. A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 3105-3109.
50. Takahashi, H., Houghten, R., Putney, S. D., Margulies, D. H., Moss, B., Germain, R. N., & Berzofsky, J. A. (1989) J. Exp. Med. 170, 2023-2035.
51. Takahashi, H., Nakagawa, Y., Pendleton, C., Houghten, R. A., Yokomuro, K., Germain, R. N., & Berzofsky, J. A. (1992) Science 255, 333-336.
52. Tsang, P., Ranee, M., Fieser, T. M., Ostresh, J. M., Houghten, R. A., Lerner, R. A., & Wright, P. E. (1992) Biochemistry 31, 3862-3871.
53. Wahren, B., Rosen, J., Sandström, E., Mathiesen, T., Modrow, S., & Wigzell, H. (1989) J. AIDS 4, 448-456.
54. Waltho, J. P., Feher, V. A., Lerner, R. A., & Wright, P. E. (1989) FEBS Lett. 250, 400-404.
55. Williamson, M. P., Hall, M. J., & Handa, B. K. (1986) Eur. J. Biochem. 158, 527-536.
56. Wishart, D. S., Sykes, B. D., & Richards, F. M. (1991) J. Mol. Biol. 222, 311-333.
57. Wright, P. E., Dyson, H. J., & Lerner, R. A. (1988) Biochemistry 27, 7167-7175.
58. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, John Wiley and Sons, New York.
59. Zvi, A., Hiller, R., & Anglister, J. (1992) Biochemistry 31, 6972-6979.