Microsatellite analysis of loss of heterozygosity on chromosomes 9q, 11 p and 17p in medulloblastomas

Neuropathology and Applied Neurobiology

Volumn 20, Issue 1, 1994, Pages 74-81

  Albrecht, S ^a,c   von Deimling, A ^a,c   Pietsch, T ^a,c   Giangaspero, F ^c   Brandner, S ^b,c   Kleihuest, P ^b,c   Wiestler, O D ^a,c  

^a UNIVERSITY OF BONN   (Germany)

^b Departments of Zürich ^*  (Swaziland)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Gorlin syndrome; loss of heterozygosity; medulloblastoma; microsatellite; polymerase chain reaction; tumour suppressor gene

Indexed keywords

DNA;

ADOLESCENT; ADULT; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BASAL CELL NEVUS SYNDROME; CHILD; CHROMOSOME 11P; CHROMOSOME 17P; CHROMOSOME 9Q; CLINICAL ARTICLE; DNA DETERMINATION; FEMALE; GENE LOCUS; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; MALE; MEDULLOBLASTOMA; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADOLESCENT; ADULT; BASAL CELL NEVUS SYNDROME; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENES, TUMOR SUPPRESSOR; HETEROZYGOTE; HUMAN; MALE; MEDULLOBLASTOMA; MIDDLE AGE; OLIGODENDROGLIA; POLYMERASE CHAIN REACTION; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0028355170     PISSN: 03051846     EISSN: 13652990     Source Type: Journal    
DOI: 10.1111/j.1365-2990.1994.tb00959.x     Document Type: Article

References (40)

1. p53 gene mutations in medulloblastoma. Immunohistochemistry, gel shift analysis, and sequencing
2. Rapid diagnosis of Miller–Dieker syndrome and isolated lissencephaly sequence by the polymerase chain reaction
3. Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors
4. Cytogenetics of human brain tumors
5. Cytogenetics and molecular genetics of malignant gliomas and medulloblastomas
6. Neuroblastoma, retinoblastoma, and brain tumors in children
7. Analysis of the VNTR locus D1S80 by the PCR followed by high–resolution PAGE
8. TP53 tumor suppressor gene: a model for investigating human mutagenesis
9. Edwards MSB, Sheffield VC. Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis
10. Deletion mapping of the medulloblastoma locus on chromosome 17p
11. The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma
12. Location of gene for Gorlin syndrome
13. Medulloblastoma: tumor biological and clinical perspectives
14. Chromosome 11p15 deletions in human malignant astrocytomas and primitive neuroectodermal tumors
15. A dinucleotide repeat polymorphism at the D9S109 locus
16. Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9
17. Nevoid basal–cell carcinoma syndrome
18. Hinfl polymorphism within the 3' untranslated region of the candidate Wilms tumour gene
19. Human Gene Mapping 11
20. Human Gene Mapping 11
21. Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism
22. Construction of a GT polymorphism map of human 9q
23. Dinucleotide repeat polymorphism at the GSN locus (9q32–34)
24. Medulloblastoma in the nevoid basal–cell carcinoma syndrome: case reports and review of the literature
25. n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens
26. Dinucleotide repeat polymorphism at the D11S490 locus
27. A dinucleotide repeat polymorphism at the D9S127 locus
28. A comprehensive genetic linkage map of the human genome
29. p53 mutations in nonastrocytic human brain tumors
30. Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa
31. Telra–nucleotide repeat polymorphism at the human tyrosine hydroxylase gene (TH)
32. Absence of p53 mutations in childhood central nervous system primitive neuroectodermal tumors
33. Genetic alterations in glioma and medulloblastoma
34. Infrequent p5 3 gene mutations in medulloblastomas
35. Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma
36. Dinucleotide repeat polymorphism at the D9S5 5 locus
37. Descriptive epidemiology of primary central nervous system tumours in children: a population–based study
38. Loss of heterozygosity on 6q. 16q, and 17p in human central nervous system primitive neuroectodermal tumors
39. Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci
40. Microsatellite polymorphism at the D9S12 locus