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Volumn 50, Issue 13, 1994, Pages 3975-3986

An expeditious asymmetric synthesis of allophenylnorstatine

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPHENYLNORSTATINE; AMINO ACID DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0028354990     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(01)89672-1     Document Type: Article
Times cited : (67)

References (25)
  • 2
    • 84914027770 scopus 로고
    • For an interesting discussion on the alternative approaches to drug therapy for HIV infection, including a section on HIV protease, see:
    • (1993) Chem Ind. (London) , pp. 746
    • Jeffries1
  • 9
    • 84988114394 scopus 로고
    • Asymmetric Synthesis of Allophenylnorstatine
    • For a preliminary communication, see:
    • (1993) Synlett , pp. 731
    • Bunnage1    Davies2    Goodwin3
  • 14
    • 84913989947 scopus 로고    scopus 로고
    • Bunnage, M.E.; Chernega, A.N.; Davies, S.G.; Goodwin, C.J. manuscript in preparation.
  • 16
    • 0000161396 scopus 로고
    • Yarnarnoto has proposed a similar chelated addition mechanism for the approach of the achiral lithium N-benzyltrimethylsilylamide (LSA) reagent to enoates, see:
    • (1990) Tetrahedron , vol.46 , pp. 4563
    • Asao1    Uyehara2    Yamamoto3
  • 18
    • 84913989946 scopus 로고    scopus 로고
    • For the majority of enoate acceptors, however, both the stepwise and the tandem procedures tend to afford the same (anti) diastereosiomer with good selectivity, see: ref. 14.
  • 23
    • 84913989945 scopus 로고    scopus 로고
    • Full details of our molecular modelling studies will be be reported in due course.
  • 25
    • 84913989944 scopus 로고    scopus 로고
    • 20 −5.4 (c 0.51, 1N HCl). However, our rotation for the TFA salt of 3 does concur with the literature value.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.