Molecular recognition in proteins. Simulation analysis of substrate binding by a tyrosyl-tRNA synthetase mutant

Journal of Molecular Biology

Volumn 236, Issue 4, 1994, Pages 1049-1066

  Lau, Frankie T K ^a   Karplus, Martin ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

free energy simulations; hydroxyl group binding; molecular recognition; mutational analyses

Indexed keywords

BACTERIA (MICROORGANISMS); GEOBACILLUS STEAROTHERMOPHILUS; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

AMINO ACID TRANSFER RNA LIGASE; MUTANT PROTEIN; TYROSINE TRANSFER RNA LIGASE;

AMINOACYLATION; ARTICLE; COMPUTER SIMULATION; ENZYME SUBSTRATE COMPLEX; GEOBACILLUS STEAROTHERMOPHILUS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL;

EID: 0028354926     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-2836(94)90011-6     Document Type: Article

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