Development of a novel drug release system, time-controlled explosion system (TES). I. Concept and design

Journal of Drug Targeting

Volumn 2, Issue 1, 1994, Pages 35-44

  Ueda, Satoshi ^a   Hata, Takehisa ^a   Asakura, Sotoo ^a   Yamaguchi, Hisami ^a   Kotani, Masateru ^a   Ueda, Yoshio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Controlled drug release system; Drug release; Lag time; Membrane destruction; Metoprolol; Time controlled explosion system (TES)

Indexed keywords

ETHYL CELLULOSE; HYDROXYPROPYLCELLULOSE; METOPROLOL; POLYMER; POLYSTYRENE;

ARTICLE; ARTIFICIAL MEMBRANE; DRUG DEVELOPMENT; DRUG RELEASE; MEMBRANE PERMEABILITY; PH; PRIORITY JOURNAL; SUSTAINED RELEASE PREPARATION; WATER PERMEABILITY;

CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; MEMBRANES, ARTIFICIAL; METOPROLOL; TENSILE STRENGTH;

EID: 0028353642     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869409015891     Document Type: Article

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