Polyol pathway mediates high glucose-induced collagen synthesis in proximal tubule

Kidney International

Volumn 45, Issue 3, 1994, Pages 659-666

  Bleyer, Anthony J ^b   Fumo, Peter ^b   Snipes, Edward R ^b   Goldfarb, Stanley ^b   Simmons, David A ^b   Ziyadeh, Fuad N ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GLUCOSE; POLYOL; SORBINIL; SORBITOL;

ANIMAL MODEL; ARTICLE; COLLAGEN SYNTHESIS; DIABETES MELLITUS; EXTRACELLULAR MATRIX; GENE CONTROL; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0028350808     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1994.88     Document Type: Article

References (55)

1. ZIYADEH FN, GOLDFARB S, KERN EFO: Diabetic nephropathy: Metabolic and biochemical mechanisms, in Contemporary Issues in Nephrology (vol 20), Churchill Livingstone, New York, 1989, pp 87-113
2. ZIYADEH FN, GOLDFARB S: The renal tubulointerstitium in diabetes mellitus. Kidney Int 39:464-475, 1991
3. STERNBERG M, COHEN-FORTERE L, PEYROUX J: Connective tissue in diabetes mellitus: Biochemical alterations of the extra-cellular matrix with special reference to proteoglycans, collagens and basement membranes. Diab et Metab 11:27-50, 1985
4. MAUER SM, STEFFES MW, ELLIS EN, SUTHERLAND DER, BROWN DM, GOETZ FC: Structural-functional relationships in diabetic nephropathy. J Clin Invest 74:1143-1155, 1984
5. LANE PH, STEFFES MW, FIORETTO P, MAUER SM: Renal interstitial expansion in insulin-dependent diabetes mellitus. Kidney Int 43:661-667, 1993
6. AYO SH, RADNIK RA, GLASS WF II, GARONI JA, RAMPT ER, APPLING DR, KREISBERG JI: Increased extracellular matrix synthesis and mRNA in mesangial cells grown in high-glucose medium. Am J Physiol 260:F185-F191, 1991
7. ZIYADEH FN: The extracellular matrix in diabetic nephropathy. Am J Kidney Dis 22:736-744, 1993
8. ZIYADEH FN: Renal tubular basement membrane and collagen type IV in diabetes mellitus. Kidney Int 43:114-120, 1993
9. IHM CG, LEE GSL, NAST CC, ARTISHEVSKY A, GUILLERMO R, LEVIN RJ, GLASSOCK RJ, ADLER SG: Early increased procollagen α1(IV) mRNA levels in streptozotocin induced diabetes. Kidney Int 41:768-777, 1992
10. ZIYADEH FN, SNIPES ER, WATANBE M, ALVAREZ RJ, GOLDFARB S, HAVERTY TP: High glucose induces cell hypertrophy and stimulates collagen gene transcription in proximal tubule. Am J Physiol 259:F704-F714, 1990
11. ZIYADEH FN, SIMMONS DA, SNIPES ER, GOLDFARB S: Effect of myo-inositol on cell proliferation and collagen transcription and secretion in proximal tubule cells cultured in elevated glucose. J Am Soc Nephrol 1:1220-1229, 1991
12. WOLF G, NEILSON EG, GOLDFARB S, ZIYADEH FN: The influence of glucose concentration on angiotensin II-induced hypertrophy of proximal tubular cells in culture. Biochem Biophys Res Commun 176:902-909, 1991
13. WINEGRAD AI: Banting Lecture 1986: Does a common mechanism induce the diverse complications of diabetes? Diabetes 36:396-406, 1987
14. SIMMONS DA, KERN EFO, WINEGRAD AI, MARTIN DB: Basal phosphatidylinositol turnover controls aortic Na/K ATPase activity. J Clin Invest 77:503-513, 1986
15. GOLDFARB S, ZIYADEH FN, KERN EFO, SIMMONS DA: Effects of polyol-pathway inhibition and dietary myo-inositol on glomerular hemodynamic function in experimental diabetes mellitus in rats. Diabetes 40:465-471, 1991
16. PEDERSON MM, CHRISTIANSEN JS, MOGENSEN CE: Reduction of glomerular hyperfiltration in normoalbuminuric IDDM patients by 6 mo of aldose reductase inhibition. Diabetes 40:527-531, 1991
17. CHANG WP, DIMITRIADIS E, ALLEN T, DUNLOP ME, COOPER M, LARKINS RG: The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus. Diabetologia 34:225-231, 1991
18. DANIELS B, HOSTETTER T: Aldose reductase inhibition and glomerular abnormalities in diabetic rats. Diabetes 38:981-986, 1989
19. MCCALEB ML, SREDY J, MILLEN J, ACKERMAN DM, DVORNIK D: Prevention of urinary albumin excretion in 6 month streptozotocin-diabetic tats with the aldose reductase inhibitor tolrestat. J Diabetic Compl 2:16-18, 1988
20. OSTERBY R, GUNDERSEN HJ: Glomerular basement membrane thickening in streptozotocin diabetic rats despite treatment with an aldose reductase inhibitor. J Diabetic Compl 3:149-153, 1989
21. POULSOM R, KURKINEN M, PROCKOP DJ, BOOT-HANFORD RP: Increased steady-state levels of laminin B1 mRNA in kidneys of long-term streptozotocin-diabetic rats. No effect of aldose reductase inhibitor. J Biol Chem 263:10072-10076, 1988
22. PATEL BN, BOOT-HANDFORD RP: Kidney levels of mRNA encoding S and B2 laminin and α1(IV) collagen in diabetic rats fed an aldose reductase inhibitor. (abstract) Biochem Soc Trans 19:367S, 1991
23. MAUER SM, STEFFES MW, AZAR S, BROWN DM: Effects of sorbinil on glomerular structure and function in long-term diabetic rats. Diabetes 38:839-846, 1989
24. HAVERTY T, KELLY CJ, HINES WH, AMENTA PS, WATANABE M, HARPER RA, KEFALIDES NA, NEILSON EG: Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J Cell Biol 107:1359-1368, 1988
25. BLAZER-YOST BL, WATANABE M, HAVERTY T, ZIYADEH FN: Role of insulin and IGF1 receptors in proliferation of cultured renal proximal tubule cells. Biochim Biophys Acta 1133:329-335, 1992
26. ROCCO M, CHEN Y, GOLDFARB S, ZIYADEH FN: Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule. Kidney Int 41:107-114, 1992
27. WOLF G, MUELLER E, STAHL RAK, ZIYADEH FN: Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous TGF-β. J Clin Invest 92:1366-1373, 1993
28. SOMOGYI M: Determination of blood sugar. J Biol Chem 160:69-73, 1945
29. ROSENTHAL N: Identification of regulatory elements of cloned genes with functional assays. Meth Enzymol, edited by SL BERGER, AR KIMMEL, Orlando, Academic, 1987, pp 704-720
30. WOLF G, KILLEN PD, NEILSON EG: Intracellular signaling of transcription and secretion of type IV collagen after angiotensin II-induced cellular hypertrophy in cultured proximal tubular cells. Cell Reg 2:219-227, 1991
31. TERUBAYASHI H, SATO S, NISHIMURA C, KADOR PF, KINOSHITA JH: Localization of aldose and aldehyde reductase in the kidney. Kidney Int 36:843-851, 1989
32. SANDS JM, TERADA Y, BERNARD LM, KNEPPER MA: Aldose reductase activities in microdissected rat renal tubule segments. Am J Physiol 256:F563-F569, 1989
33. +. Kidney Int 41:778-788, 1992
34. CLEMENTS R, WEAVER J, WINEGRAD A: The distribution of polyol: NADP oxidoreductase in mammalian tissues. Biochem Biophys Res Comm 37:347-353, 1969
35. CORDER C, COLLINS J, BRANNAN T, SHARMA J: Aldose reductase and sorbitol dehydrogenase distribution in rat kidney. J Histochem Cytochem 25:1-8, 1977
36. KLEINZELLER A, ZIYADEH FN: Cell volume regulation in epithelia with emphasis on the role of osmolytes and the cytoskeleton. Comparative Physiol 4:59-86, 1990
37. LUDVIGSON MA, SORENSON RL: Immunohistochemical localization of aldose reductase. Diabetes 29:450-459, 1980
38. MORIYAMA T, MURPHY HR, MARTIN BM, GARCIA-PEREZ A: Detection of specific mRNAs in single nephron segments by use of the polymerase chain reaction. Am J Physiol 258:F1470-F1474, 1990
39. HUTTON J, WILLIAMS J, SCHOFIELD P, HOLLOWS F: Polyol metabolism in monkey-kidney epithelial-cell cultures. Eur J Biochem 49:347-353, 1974
40. BYLANDER J, SENS D: Elicitation of sorbitol accumulation in cultured human proximal tubule cells by elevated glucose concentrations. Diabetes 39:949-954, 1990
41. PETRASH JM, FLATH M, SENS D, BYLANDER J: Effects of osmotic stress and hyperglycemia on aldose reductase gene expression in human renal proximal tubule cells. Biochem Biophys Res Commun 187:201-208, 1992
42. BADER R, BADER H, GRUND KE, MARKENSEN-HAEN S, CHRIST H, BOHLE A: Structure and function of the kidney in diabetic glomerulosclerosis: Correlations between morphologic and functional parameters. Pathol Res Practice 167:204-216, 1980
43. BOHLE A, BADER R, GRUND KE, MAKENSEN S, TOLON M: Correlations between renal interstitium and level of serum creatinine. Morphometric investigations of biopsies in perimembranous glomerulonephritis. Virchows Arch A Path Anat Histol 373:15-22, 1977
44. FROKJAER-THOMSEN O, ANDERSEN A, CHRISTIANSEN JS, DECKERT T: Renal changes in long-term type 1 (insulin-dependent) diabetic patients with and without clinical nephropathy: A light microscopic, morphometric study of autopsy material. Diabetologia 26:361-365, 1988
45. STEFFES MW, SUTHERLAND DER, GOETZ FC, RICH SS, MAUER SM: Studies of kidney and muscle biopsy specimens from identical twins discordant for type I diabetes mellitus. N Engl J Med 312:1282-1287, 1985
46. DESJARDINS M, GROS F, WIESLANDER J, GUBLER MC, BENDAYAN M: Immunogold studies of monomeric elements from the globular domain (NC1) of type IV collagen in renal basement membranes during experimental diabetes in the rat. Diabetologia 33:661-670, 1990
47. CRAVEN P, DAVIDSON C, DERUBERTIS F: Increase in diacylglycerol mass in isolated glomeruli by glucose from de novo synthesis of glycerolipids. Diabetes 39:667-674, 1990
48. AYO SH, RADNIK R, GARONI JA: High glucose increases diacylglycerol mass and activates protein kinases C in mesangial cell culture. Am J Physiol 261:F571-F577, 1991
49. DRUMMOND A, RAEBURN C: The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Biochem J 224:129-136, 1984
50. DOWNES C, STONE M: Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland. Biochem J 234:199-204, 1986
51. BERRIDGE M, DOWNES C, HANLEY M: Neural and developmental actions of lithium: A unifying hypothesis. Cell 59:411-419, 1989
52. PETERSEN A, SZWERGOLD BS, KAPPLER F, WEINGARTEN M, BROWN TR: Identification of sorbitol 3-phosphate and fructose 3-phosphate in normal and diabetic human erythrocytes. J Biol Chem 265:17424-17427, 1990
53. SUAREZ G, RAJARAM R, BHUYAN KC, ORONSKY AL, GOIDI JA: Administration of an aldose reductase inhibitor induces a decrease of collagen fluorescence in diabetic rats. J Clin Invest 82:624-627, 1988
54. SZWERGOLD BS, KAPPLER F, BROWN TR: Identification of fructose 3-phosphate in the lens of diabetic rats. Science 247:451-454, 1990
55. COHEN MP, ZIYADEH FN: Amadori glucose adducts modulate mesangial cell growth and collagen gene expression Kidney Int 45:475-484, 1994