L-DOPA increases nigral production of hydroxyl radicals in vivo: Otential L-DOPA toxicity?

NeuroReport

Volumn 5, Issue 8, 1994, Pages 1009-1011

  Smith, Trisha Spencer ^a   Parker, W D ^a   Bennett, James P ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Free radicals; L DOPA; Neurotoxicity; Parkinson s disease

Indexed keywords

CARBIDOPA; FREE RADICAL; HYDROXYL RADICAL; LEVODOPA; SELEGILINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; HOMOVANILLIC ACID; HYDROXYL RADICAL; LEVODOPA; MICRODIALYSIS; MITOCHONDRIA; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; SELEGILINE; STEREOTAXIC TECHNIQUES; SUBSTANTIA NIGRA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028350560     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/00001756-199404000-00039     Document Type: Article

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