(R,R)-2,2′-[1,2-Ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]-bis[5-nitro-1Hbenz[de]isoquinoline-1,3-(2H)-dione] Dimethanesulfonate (DMP 840), a Novel Bis-naphthalimide with Potent Nonselective Tumoricidal Activity in Vitro

Cancer Research

Volumn 54, Issue 8, 1994, Pages 2199-2206

  Kirshenbaum, M R ^a   Chen, S F ^a   Behrens, C H ^b   Papp, L M ^a   Stafford, M M ^a   Sun, J H ^b   Behrens, D L ^a   Fredericks, J R ^a   Polkus, S T ^a   Sipple, P ^a   Patten, A D ^b   Dexter, D ^a   Seitz, S P ^b   Gross, J L ^a  

^a Molecular Biology Division   (United States)

^b Wilmington ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2' [1,2 ETHANEDIYLBIS[IMINO(1 METHYL 2,1 ETHANEDIYL)]]BIS(5 NITRO 1H BENZ[DE]ISOQUINOLINE 1,3(2H) DIONE) DIMETHANESULFONATE; ANTINEOPLASTIC AGENT; BISNAFIDE MESYLATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; COLON CARCINOMA; CONTROLLED STUDY; CROSS RESISTANCE; DNA STRAND BREAKAGE; DNA SYNTHESIS; DOSE RESPONSE; DRUG MECHANISM; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; RNA SYNTHESIS;

AMSACRINE; ANIMAL; ANTINEOPLASTIC AGENTS; CELL DIVISION; CLINICAL TRIALS, PHASE I; COLONIC NEOPLASMS; DACTINOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMAN; ISOQUINOLINES; KB CELLS; KINETICS; LEUCINE; LEUKEMIA L1210; LEUKEMIA P388; MAMMARY NEOPLASMS, EXPERIMENTAL; MELANOMA; MELANOMA, EXPERIMENTAL; MESYLATES; MICE; MITOXANTRONE; THYMIDINE; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; URIDINE;

EID: 0028348380     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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